lOMoAR cPSD| 47061011
Nur2474 pharmacology module 5 quiz review
Questions and Answers with 100% Complete
Solutions UPDATED!!!
Test tips:
Before answering the question, identify key words (what
does the question really ask).
Be cautious of negatively worded questions! They are easy,
but often misinterpreted due to not paying attention to them.
Topics review:
1.Diuretics mechanism of action (including effects on
electrolytes)
a. Diuretics work by preventing kidney reabsorption of
sodium and chloride therefore preventing absorption
of water.
i. Hypovolemia
ii. Acid-base imbalance iii.
Electrolyte imbalance
2.Diuretics intended use
a. Cleansing of ECF and maintenance of ECF volume
and composition
b. Maintenance of acid-base balance
c. Excretion of metabolic wastes and foreign substances
d. Increase amount of salt and water expelled from the
body as urine
, lOMoAR cPSD| 47061011
e. Can also be used to treat hypertension, edema,
diabetes insipidus, CHF
3. Review furosemide (mechanism of action, side and
adverse effects, administration, monitoring, food/drug
interactions)
a. Mechanism of action
i. Loop Diuretic
ii. Acts on ascending loop of Henle to block
reabsorption
b. Side/adverse effects
i. Hyponatremia
ii. Hypochloremia
iii. Dehydration
iv. Hypotension
1. Loss of volume
2. Relaxation of venous smooth muscle
v.Hypokalemia
vi.Ototoxicity
vii. Hyperglycemia
viii. Hyperuricemia (excess of uric acid in
blood) ix. Use in pregnancy
x.Impact on lipids, calcium, and magnesium
c. Administration
i.Rapid onset
1. PO- 60 minutes
2. IV- 5 minutes ii.
Administer in the morning
, lOMoAR cPSD| 47061011
1.Make you pee a lot, interfere with sleep
pattern
d. Monitoring
i. Monitor blood sugar levels
ii. Monitor electrolytes
iii. EKG
iv. Dehydration
v. Fall risk due to hypotension
vi. Furosemide and gentamicin (antibiotic)
should not be mixed due to acoustic damage
—
tinnitus vii.
Kidney
function
1.Creatinine
a. 0.84 to
1.21 mg/dl 2.
Creatinine
clearance:
a. Men—110 to 150 ml/min
b. Women—100 to 130 ml/min
3. Bun
a.10-20 mg/dl
e. Food/drug interactions
i. Digoxin
ii. Ototoxic drugs
iii. Potassium-sparing diuretics
iv. Lithium
Nur2474 pharmacology module 5 quiz review
Questions and Answers with 100% Complete
Solutions UPDATED!!!
Test tips:
Before answering the question, identify key words (what
does the question really ask).
Be cautious of negatively worded questions! They are easy,
but often misinterpreted due to not paying attention to them.
Topics review:
1.Diuretics mechanism of action (including effects on
electrolytes)
a. Diuretics work by preventing kidney reabsorption of
sodium and chloride therefore preventing absorption
of water.
i. Hypovolemia
ii. Acid-base imbalance iii.
Electrolyte imbalance
2.Diuretics intended use
a. Cleansing of ECF and maintenance of ECF volume
and composition
b. Maintenance of acid-base balance
c. Excretion of metabolic wastes and foreign substances
d. Increase amount of salt and water expelled from the
body as urine
, lOMoAR cPSD| 47061011
e. Can also be used to treat hypertension, edema,
diabetes insipidus, CHF
3. Review furosemide (mechanism of action, side and
adverse effects, administration, monitoring, food/drug
interactions)
a. Mechanism of action
i. Loop Diuretic
ii. Acts on ascending loop of Henle to block
reabsorption
b. Side/adverse effects
i. Hyponatremia
ii. Hypochloremia
iii. Dehydration
iv. Hypotension
1. Loss of volume
2. Relaxation of venous smooth muscle
v.Hypokalemia
vi.Ototoxicity
vii. Hyperglycemia
viii. Hyperuricemia (excess of uric acid in
blood) ix. Use in pregnancy
x.Impact on lipids, calcium, and magnesium
c. Administration
i.Rapid onset
1. PO- 60 minutes
2. IV- 5 minutes ii.
Administer in the morning
, lOMoAR cPSD| 47061011
1.Make you pee a lot, interfere with sleep
pattern
d. Monitoring
i. Monitor blood sugar levels
ii. Monitor electrolytes
iii. EKG
iv. Dehydration
v. Fall risk due to hypotension
vi. Furosemide and gentamicin (antibiotic)
should not be mixed due to acoustic damage
—
tinnitus vii.
Kidney
function
1.Creatinine
a. 0.84 to
1.21 mg/dl 2.
Creatinine
clearance:
a. Men—110 to 150 ml/min
b. Women—100 to 130 ml/min
3. Bun
a.10-20 mg/dl
e. Food/drug interactions
i. Digoxin
ii. Ototoxic drugs
iii. Potassium-sparing diuretics
iv. Lithium
