9/6/25, 6:53 AM Galen NUR 210 Exam 1 Modules 1-3 EXAM Questions & Answers, Well Elaborated | Already Verified Test |100% Verified solutions | …
Galen NUR 210 Exam 1 Modules 1-3 EXAM
Questions & Answers, Well Elaborated | Already
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Terms in this set (103)
The process in which medications move through the
Pharmacokinetics
body
What are the 4 phases of absorption, distribution, metabolism, excretion
pharmacokinetics?
happens with drug movement from the GI tract into
Absorption
the bloodstream. Most meds are taken by mouth.
Takes awhile to get absorbed because it has to go
through the GI system
Usually takes 2-4 hours
Oral absorption •Enteric coated
aspirin - hard on stomach
can not crush pill
•Extended release
absorbed in the small intestine
IM absorption Absorbed 1-2 hours
IV absorption Absorbed 30-60 minutes
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Dissolution happens when a po medication breaks
down into particles, disintegrates, and dissolves to
combine with liquid so absorption from the GI tract
dissolution
into the bloodstream occurs.
Liquid medications are absorbed faster than solids.
Food can interfere with the absorption of drugs.
Parenteral medications (SL, eyedrops, inhalants,
transdermal) do not pass through the GI tract.
Drugs that resist Enteric coated medications are designed to resist
dissolution disintegration until the pill reaches the small intestine.
EC and sustained release meds should not be
crushed.
•Lack of muscle and increased fat changes medicine
absorption
•Food consumption - will change medicine potency
Factors that affect (delayed)
absorption •Stress - Exercise, medicine goes to muscle
•pH - Medicine is made for acidic environments
•Antacid changes absorption
•Taken alone so it doesn't change the action
Fillers and other substances that make up tablets as a
pill is not 100% drug.
Sometimes an excipient enhances the absorption of a
Excipients drug such as with PCN, which is not well absorbed
from the GI tract.
Adding Na to PCN, which makes it penicillin sodium,
will increase the absorption of PCN
•the oral drugs go to liver via portal vein where some
first pass effect of the drug becomes inactive
•Only happens with oral medications
delayed gastric emptying Food doesn't move like it should
refers to the movement of the drug from the
Distribution
circulation to body tissues
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-blood flow to tissues
Factors affecting -protein binding
distribution -blood brain barrier
-drug's affinity to the tissue
Drugs bind with proteins in blood
protein binding Some drugs are highly protein bound and other are
weakly protein bound
free drugs drugs not bound to protein
-Two highly protein bound drugs compete and one
might accumulate and cause a toxicity
-it is important to know if you are administering highly
protein bound medications and monitor albumin
Drug Toxicity levels in patients with liver or kidney disease.
-Some drugs that are highly protein bound include:
Warfarin
Furosemide
Diazepam
-A decrease in albumin levels decrease the protein-
binding sites, which means more of the free drug is
circulated.
-This can be fatal with some meds.
Drug distribution and
-Free drugs are those not bound to protein, which
albumin
means they are active in the body and cause a
pharmacologic response.
-Older adults, malnourished individuals, and those
with liver or kidney disease have low albumin levels.
-The BBB protects the brain from most drugs.
-Some meds are able to cross the BBB such as
benzodiazepines.
Blood Brain Barrier (BBB)
-Drugs can cross the placenta and cause
spontaneous abortion or alter fetal growth and
development.
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Galen NUR 210 Exam 1 Modules 1-3 EXAM
Questions & Answers, Well Elaborated | Already
Verified Test |100% Verified solutions | 2025\2026
Latest!!
Save
Terms in this set (103)
The process in which medications move through the
Pharmacokinetics
body
What are the 4 phases of absorption, distribution, metabolism, excretion
pharmacokinetics?
happens with drug movement from the GI tract into
Absorption
the bloodstream. Most meds are taken by mouth.
Takes awhile to get absorbed because it has to go
through the GI system
Usually takes 2-4 hours
Oral absorption •Enteric coated
aspirin - hard on stomach
can not crush pill
•Extended release
absorbed in the small intestine
IM absorption Absorbed 1-2 hours
IV absorption Absorbed 30-60 minutes
https://quizlet.com/1072292903/galen-nur-210-exam-1-modules-1-3-exam-questions-answers-well-elaborated-already-verified-test-100-verified-soluti… 1/24
,9/6/25, 6:53 AM Galen NUR 210 Exam 1 Modules 1-3 EXAM Questions & Answers, Well Elaborated | Already Verified Test |100% Verified solutions | …
Dissolution happens when a po medication breaks
down into particles, disintegrates, and dissolves to
combine with liquid so absorption from the GI tract
dissolution
into the bloodstream occurs.
Liquid medications are absorbed faster than solids.
Food can interfere with the absorption of drugs.
Parenteral medications (SL, eyedrops, inhalants,
transdermal) do not pass through the GI tract.
Drugs that resist Enteric coated medications are designed to resist
dissolution disintegration until the pill reaches the small intestine.
EC and sustained release meds should not be
crushed.
•Lack of muscle and increased fat changes medicine
absorption
•Food consumption - will change medicine potency
Factors that affect (delayed)
absorption •Stress - Exercise, medicine goes to muscle
•pH - Medicine is made for acidic environments
•Antacid changes absorption
•Taken alone so it doesn't change the action
Fillers and other substances that make up tablets as a
pill is not 100% drug.
Sometimes an excipient enhances the absorption of a
Excipients drug such as with PCN, which is not well absorbed
from the GI tract.
Adding Na to PCN, which makes it penicillin sodium,
will increase the absorption of PCN
•the oral drugs go to liver via portal vein where some
first pass effect of the drug becomes inactive
•Only happens with oral medications
delayed gastric emptying Food doesn't move like it should
refers to the movement of the drug from the
Distribution
circulation to body tissues
https://quizlet.com/1072292903/galen-nur-210-exam-1-modules-1-3-exam-questions-answers-well-elaborated-already-verified-test-100-verified-soluti… 2/24
, 9/6/25, 6:53 AM Galen NUR 210 Exam 1 Modules 1-3 EXAM Questions & Answers, Well Elaborated | Already Verified Test |100% Verified solutions | …
-blood flow to tissues
Factors affecting -protein binding
distribution -blood brain barrier
-drug's affinity to the tissue
Drugs bind with proteins in blood
protein binding Some drugs are highly protein bound and other are
weakly protein bound
free drugs drugs not bound to protein
-Two highly protein bound drugs compete and one
might accumulate and cause a toxicity
-it is important to know if you are administering highly
protein bound medications and monitor albumin
Drug Toxicity levels in patients with liver or kidney disease.
-Some drugs that are highly protein bound include:
Warfarin
Furosemide
Diazepam
-A decrease in albumin levels decrease the protein-
binding sites, which means more of the free drug is
circulated.
-This can be fatal with some meds.
Drug distribution and
-Free drugs are those not bound to protein, which
albumin
means they are active in the body and cause a
pharmacologic response.
-Older adults, malnourished individuals, and those
with liver or kidney disease have low albumin levels.
-The BBB protects the brain from most drugs.
-Some meds are able to cross the BBB such as
benzodiazepines.
Blood Brain Barrier (BBB)
-Drugs can cross the placenta and cause
spontaneous abortion or alter fetal growth and
development.
https://quizlet.com/1072292903/galen-nur-210-exam-1-modules-1-3-exam-questions-answers-well-elaborated-already-verified-test-100-verified-soluti… 3/24
