Verified Questions with 100% Correct
Answers, A+ Graded Nurse Practitioner
Board Review
Section 1: Clinical Assessment and Diagnosis (40 Questions)
1. Question: A 22-year-old female presents with a 3-day history of fever, sore throat, and
cervical lymphadenopathy. What is the most likely diagnosis?
Answer: Infectious mononucleosis
Rationale: Classic triad of fever, pharyngitis, and lymphadenopathy suggests
mononucleosis, often caused by Epstein-Barr virus.
2. Question: A 45-year-old male has a blood pressure of 150/90 mmHg. What is the first
step in management?
Answer: Lifestyle modifications
Rationale: Stage 1 hypertension (140–159/90–99) starts with lifestyle changes per JNC-8
guidelines.
3. Question: A 6-year-old presents with a barking cough and inspiratory stridor. What is the
most likely diagnosis?
Answer: Croup
Rationale: Barking cough and stridor are hallmark signs of croup, typically viral
(parainfluenza).
4. Question: A 60-year-old female reports chest pain radiating to the left arm. What is the
priority action?
Answer: Order an ECG
Rationale: Chest pain with radiation suggests possible myocardial infarction; ECG is
critical for diagnosis.
5. Question: A 30-year-old with type 1 diabetes reports nausea and fruity breath odor. What
is the likely diagnosis?
Answer: Diabetic ketoacidosis
Rationale: Fruity breath and nausea indicate DKA, a medical emergency in type 1
diabetes.
6. Question: A 50-year-old male has a PSA of 5.0 ng/mL. What is the next step?
Answer: Refer for prostate biopsy
Rationale: PSA >4.0 ng/mL warrants further evaluation for prostate cancer.
7. Question: A 2-year-old has a fever and a red, bulging tympanic membrane. What is the
diagnosis?
Answer: Acute otitis media
Rationale: Fever and bulging tympanic membrane are classic for bacterial otitis media.
, 8. Question: A 35-year-old female reports fatigue and weight gain. TSH is 6.5 mIU/L.
What is the diagnosis?
Answer: Hypothyroidism
Rationale: Elevated TSH with symptoms indicates primary hypothyroidism.
9. Question: A 25-year-old presents with a fine, pink rash after 3 days of fever. What is the
likely diagnosis?
Answer: Roseola
Rationale: Fever followed by a rash is characteristic of roseola (herpesvirus 6).
10. Question: A 70-year-old male has a productive cough and night sweats. What test should
be ordered?
Answer: Sputum culture for TB
Rationale: Symptoms suggest tuberculosis; sputum culture confirms diagnosis.
11. Question: A 40-year-old female reports unilateral knee pain and swelling. What is a
likely cause?
Answer: Meniscal injury
Rationale: Unilateral knee pain with swelling often indicates a meniscal tear, especially
with activity.
12. Question: A 55-year-old with chest pain has a normal ECG. What is the next step?
Answer: Order a stress test
Rationale: Normal ECG does not rule out angina; a stress test assesses cardiac function.
13. Question: A 10-year-old has a sore throat and positive rapid strep test. What is the
treatment?
Answer: Amoxicillin
Rationale: Amoxicillin is first-line for streptococcal pharyngitis to prevent
complications.
14. Question: A 65-year-old female has a calcium level of 11.0 mg/dL. What is the likely
cause?
Answer: Hyperparathyroidism
Rationale: Hypercalcemia in older adults is commonly due to primary
hyperparathyroidism.
15. Question: A 28-year-old female reports pelvic pain and abnormal vaginal discharge.
What is the diagnosis?
Answer: Pelvic inflammatory disease
Rationale: Pelvic pain and discharge suggest PID, often due to chlamydia or gonorrhea.
16. Question: A 45-year-old male has a fasting glucose of 130 mg/dL. What is the
diagnosis?
Answer: Type 2 diabetes
Rationale: Fasting glucose ≥126 mg/dL confirms diabetes per ADA guidelines.
17. Question: A 3-year-old has wheezing and a history of eczema. What is the likely
diagnosis?
Answer: Asthma
Rationale: Wheezing with an atopic history (eczema) suggests asthma in children.
18. Question: A 50-year-old male reports epigastric pain relieved by eating. What is the
likely diagnosis?
Answer: Duodenal ulcer