NURS5220 EXAM 3 Questions With 100%
Correct Verified Answers Graded A+ Exam
Latest Versions 2025
What are the adverse effects of midazolam? - ✔✔✔
Correct Answer > Prolonged sedation, impaired cognition and
psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and
withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer >
They increase the threshold to local anesthetic-induced
seizures.
Which benzodiazepines have no active metabolites? -
✔✔✔ Correct Answer > Oxazepam, lorazepam, and
temazepam.
What factors can alter the metabolism of benzodiazepines? -
✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily
determined by? - ✔✔✔ Correct Answer > The α phase
(distribution-redistribution from CNS) dynamics rather than
the rate of elimination.
What are the pharmacodynamic effects of benzodiazepines on
the CNS? - ✔✔✔ Correct Answer > CNS depressant effects
including anxiolysis, sedation, sleep, anticonvulsant, amnesia,
muscle relaxation, and inhibition of alcohol withdrawal
symptoms.
What is the dose-related effect of benzodiazepines on
anterograde amnesia? - ✔✔✔ Correct Answer > They
cause anterograde amnesia at high doses.
What are the potential drawbacks of benzodiazepine use? -
✔✔✔
Correct Answer > Awareness regarding addiction, withdrawal,
recreational abuse, and the development of other drug classes
has led to a decline in their use.
,Which CYP enzyme is primarily responsible for the
metabolism of benzodiazepines? - ✔✔✔ Correct Answer >
CYP3A4.
Which benzodiazepine has a half-life exceeding 100 hours? -
✔✔✔
Correct Answer > Diazepam.
Which benzodiazepine is rapidly metabolized to an α-
hydroxylated compound with biologic activity? - ✔✔✔
Correct Answer > Midazolam.
Which benzodiazepines have no active metabolites? -
✔✔✔ Correct Answer > Oxazepam, lorazepam, and
temazepam.
What is the primary factor determining the duration of action
of benzodiazepines? - ✔✔✔ Correct Answer > The α phase
dynamics of distribution-redistribution from the CNS.
, What are the CNS depressant effects of benzodiazepines? -
✔✔✔ Correct Answer > Anxiolysis, sedation, sleep,
anticonvulsant, amnesia, muscle relaxation, and inhibition of
alcohol withdrawal symptoms.
What effect do high doses of benzodiazepines have on CMR02
& CBF? -
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer >
They increase the threshold to local anesthetic-induced
seizures.
What is the dose-related effect of benzodiazepines on
anterograde amnesia? - ✔✔✔ Correct Answer > They
cause anterograde amnesia at high doses.
Correct Verified Answers Graded A+ Exam
Latest Versions 2025
What are the adverse effects of midazolam? - ✔✔✔
Correct Answer > Prolonged sedation, impaired cognition and
psychomotor performance, unwanted amnesia, potential for
delirium, increased risk of accidents and falls, dependence and
withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer >
They increase the threshold to local anesthetic-induced
seizures.
Which benzodiazepines have no active metabolites? -
✔✔✔ Correct Answer > Oxazepam, lorazepam, and
temazepam.
What factors can alter the metabolism of benzodiazepines? -
✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily
determined by? - ✔✔✔ Correct Answer > The α phase
(distribution-redistribution from CNS) dynamics rather than
the rate of elimination.
What are the pharmacodynamic effects of benzodiazepines on
the CNS? - ✔✔✔ Correct Answer > CNS depressant effects
including anxiolysis, sedation, sleep, anticonvulsant, amnesia,
muscle relaxation, and inhibition of alcohol withdrawal
symptoms.
What is the dose-related effect of benzodiazepines on
anterograde amnesia? - ✔✔✔ Correct Answer > They
cause anterograde amnesia at high doses.
What are the potential drawbacks of benzodiazepine use? -
✔✔✔
Correct Answer > Awareness regarding addiction, withdrawal,
recreational abuse, and the development of other drug classes
has led to a decline in their use.
,Which CYP enzyme is primarily responsible for the
metabolism of benzodiazepines? - ✔✔✔ Correct Answer >
CYP3A4.
Which benzodiazepine has a half-life exceeding 100 hours? -
✔✔✔
Correct Answer > Diazepam.
Which benzodiazepine is rapidly metabolized to an α-
hydroxylated compound with biologic activity? - ✔✔✔
Correct Answer > Midazolam.
Which benzodiazepines have no active metabolites? -
✔✔✔ Correct Answer > Oxazepam, lorazepam, and
temazepam.
What is the primary factor determining the duration of action
of benzodiazepines? - ✔✔✔ Correct Answer > The α phase
dynamics of distribution-redistribution from the CNS.
, What are the CNS depressant effects of benzodiazepines? -
✔✔✔ Correct Answer > Anxiolysis, sedation, sleep,
anticonvulsant, amnesia, muscle relaxation, and inhibition of
alcohol withdrawal symptoms.
What effect do high doses of benzodiazepines have on CMR02
& CBF? -
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer >
They increase the threshold to local anesthetic-induced
seizures.
What is the dose-related effect of benzodiazepines on
anterograde amnesia? - ✔✔✔ Correct Answer > They
cause anterograde amnesia at high doses.
