, Page 2 of 822 yr yr yr
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
yr yr yr yr yr yr yr yr y r
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
yr yr yr yr yr yr yr yr yr yr yr
1.
A nurse working in radiology administers iodine to a patient who is havin
yr yr yr yr yr yr yr yr yr yr yr yr
g a computed tomography (CT) scan. The nurse working on the oncology u
yr yr yr yr yr yr yr yr yr yr yr yr
nit administers chemotherapy to patients who have cancer. At the Public He
yr yr yr yr yr yr yr yr yr yr yr
alth Department, a nurse administers a measles-mumps-
yr yr yr yr yr yr
rubella (MMR) vaccine to a 14-month-
yr yr yr yr yr
old child as a routine immunization. Which branch of pharmacology best de
yr yr yr yr yr yr yr yr yr yr yr
scribes the actions of all three nurses?
yr yr yr yr yr y r
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are i
yr yr yr yr yr yr yr yr yr yr yr yr
nvolved with clinical pharmacology or pharmacotherapeutics, which is a bra
yr yr yr yr yr yr yr yr yr
nch of pharmacology that deals with the uses of drugs to treat, prevent, and
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
diagnose disease. The radiology nurse is administering a drug to help diagn
yr yr yr yr yr yr yr yr yr yr yr
ose a disease. The oncology nurse is administering a drug to help treat a dise
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
ase. Pharmacoeconomics includes any costs involved in drug therapy.
yr yr yr yr yr yr yr yr
Pharmacodynamics involves how a drug affects the body and pharmacokinetic yr yr yr yr yr yr yr yr yr
s is how the body acts on the body.
yr yr yr yr yr yr yr yr
2.
When involved in phase III drug evaluation studies, wh
yr yr yr yr yr yr yr yr
at responsibilities would the nurse have?
yr yr yr yr yr
A) Working with animals who are given experimental drugs
yr yr yr yr yr yr yr
B) Choosing appropriate patients to be involved in the drug study
yr yr yr yr yr yr yr yr yr
C) Monitoring and observing patients closely for adverse effects
yr yr yr yr yr yr yr
D) Conducting research to determine effectiveness of the drug
yr yr yr yr yr yr yr
, Page 3 of 822 yr yr yr
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
yr yr yr yr yr yr yr yr yr yr yr yr yr yr yr
patients are asked to record any symptoms they experience while taking the
yr yr yr yr yr yr yr yr yr yr yr yr
drugs. Nurses may be responsible for helping collect and analyze the infor
yr yr yr yr yr yr yr yr yr yr yr
mation to be shared with the Food and Drug Administration (FDA) but woul
yr yr yr yr yr yr yr yr yr yr yr yr
d not conduct research independently because nurses do not prescribe medi
yr yr yr yr yr yr yr yr yr yr
cations. Use of animals in drug testing is done in the preclinical trials. Selec
yr yr yr yr yr yr yr yr yr yr yr yr yr
t patients who are involved in phase II studies to participate in studies wher
yr yr yr yr yr yr yr yr yr yr yr yr yr
e the participants have the disease the drug is intended to treat. These patien
yr yr yr yr yr yr yr yr yr yr yr yr yr
ts are monitored closely for drug action and adverse effects. Phase I studies
yr yr yr yr yr yr yr yr yr yr yr yr yr
involve healthy human volunteers who are usually paid for their participatio
yr yr yr yr yr yr yr yr yr yr
n. Nurses may observe for adverse effects and toxicity.
yr yr yr yr yr yr yr yr
3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
yr yr yr yr yr yr yr yr yr yr
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. T
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
he nurse is aware this drug has a high abuse potential. Under what category
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
would morphine be classified? yr yr yr
A) Schedule I yr
B) Schedule II yr
C) Schedule III yr
D) Schedule IV yr
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs be
yr yr yr yr yr yr yr yr yr yr yr yr
cause of severe dependence liability. Schedule I drugs have high abuse pot
yr yr yr yr yr yr yr yr yr yr yr
ential and no accepted medical use. Schedule III drugs have a lesser abuse
yr yr yr yr yr yr yr yr yr yr yr yr yr
potential than II and an accepted medical use. Schedule IV drugs have low a
yr yr yr yr yr yr yr yr yr yr yr yr yr
buse potential and limited dependence liability.
yr yr yr yr yr
4.
What concept is considered when generic drugs are substituted for bra
yr yr yr yr yr yr yr yr yr yr
nd name drugs?
yr yr
A) Bioavailability
, WWW.THENURSINGMASTERY.
www.stuvia.com
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
yr yr yr yr yr yr yr yr y r
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
yr yr yr yr yr yr yr yr yr yr yr
1.
A nurse working in radiology administers iodine to a patient who is havin
yr yr yr yr yr yr yr yr yr yr yr yr
g a computed tomography (CT) scan. The nurse working on the oncology u
yr yr yr yr yr yr yr yr yr yr yr yr
nit administers chemotherapy to patients who have cancer. At the Public He
yr yr yr yr yr yr yr yr yr yr yr
alth Department, a nurse administers a measles-mumps-
yr yr yr yr yr yr
rubella (MMR) vaccine to a 14-month-
yr yr yr yr yr
old child as a routine immunization. Which branch of pharmacology best de
yr yr yr yr yr yr yr yr yr yr yr
scribes the actions of all three nurses?
yr yr yr yr yr y r
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are i
yr yr yr yr yr yr yr yr yr yr yr yr
nvolved with clinical pharmacology or pharmacotherapeutics, which is a bra
yr yr yr yr yr yr yr yr yr
nch of pharmacology that deals with the uses of drugs to treat, prevent, and
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
diagnose disease. The radiology nurse is administering a drug to help diagn
yr yr yr yr yr yr yr yr yr yr yr
ose a disease. The oncology nurse is administering a drug to help treat a dise
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
ase. Pharmacoeconomics includes any costs involved in drug therapy.
yr yr yr yr yr yr yr yr
Pharmacodynamics involves how a drug affects the body and pharmacokinetic yr yr yr yr yr yr yr yr yr
s is how the body acts on the body.
yr yr yr yr yr yr yr yr
2.
When involved in phase III drug evaluation studies, wh
yr yr yr yr yr yr yr yr
at responsibilities would the nurse have?
yr yr yr yr yr
A) Working with animals who are given experimental drugs
yr yr yr yr yr yr yr
B) Choosing appropriate patients to be involved in the drug study
yr yr yr yr yr yr yr yr yr
C) Monitoring and observing patients closely for adverse effects
yr yr yr yr yr yr yr
D) Conducting research to determine effectiveness of the drug
yr yr yr yr yr yr yr
, Page 3 of 822 yr yr yr
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
yr yr yr yr yr yr yr yr yr yr yr yr yr yr yr
patients are asked to record any symptoms they experience while taking the
yr yr yr yr yr yr yr yr yr yr yr yr
drugs. Nurses may be responsible for helping collect and analyze the infor
yr yr yr yr yr yr yr yr yr yr yr
mation to be shared with the Food and Drug Administration (FDA) but woul
yr yr yr yr yr yr yr yr yr yr yr yr
d not conduct research independently because nurses do not prescribe medi
yr yr yr yr yr yr yr yr yr yr
cations. Use of animals in drug testing is done in the preclinical trials. Selec
yr yr yr yr yr yr yr yr yr yr yr yr yr
t patients who are involved in phase II studies to participate in studies wher
yr yr yr yr yr yr yr yr yr yr yr yr yr
e the participants have the disease the drug is intended to treat. These patien
yr yr yr yr yr yr yr yr yr yr yr yr yr
ts are monitored closely for drug action and adverse effects. Phase I studies
yr yr yr yr yr yr yr yr yr yr yr yr yr
involve healthy human volunteers who are usually paid for their participatio
yr yr yr yr yr yr yr yr yr yr
n. Nurses may observe for adverse effects and toxicity.
yr yr yr yr yr yr yr yr
3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
yr yr yr yr yr yr yr yr yr yr
cotic, every 4 hours as needed for pain in a motor vehicle accident victim. T
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
he nurse is aware this drug has a high abuse potential. Under what category
yr yr yr yr yr yr yr yr yr yr yr yr yr yr
would morphine be classified? yr yr yr
A) Schedule I yr
B) Schedule II yr
C) Schedule III yr
D) Schedule IV yr
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs be
yr yr yr yr yr yr yr yr yr yr yr yr
cause of severe dependence liability. Schedule I drugs have high abuse pot
yr yr yr yr yr yr yr yr yr yr yr
ential and no accepted medical use. Schedule III drugs have a lesser abuse
yr yr yr yr yr yr yr yr yr yr yr yr yr
potential than II and an accepted medical use. Schedule IV drugs have low a
yr yr yr yr yr yr yr yr yr yr yr yr yr
buse potential and limited dependence liability.
yr yr yr yr yr
4.
What concept is considered when generic drugs are substituted for bra
yr yr yr yr yr yr yr yr yr yr
nd name drugs?
yr yr
A) Bioavailability
, WWW.THENURSINGMASTERY.
www.stuvia.com
