CHE 4342 EXAM QUESTIONS AND 100%
CORRECT ANSWERS!!
What is the continuous phase of the biological membrane
fluid lipid bilayer
What is the discontinuous phase in the plasma membrane
proteins floating in the lipids
What is the mosaic in the plasma membrane
made up of many different parts, proteins that interact with the lipid bilayer by electrostatic
interactions and proteins that span the membrane
Can lipids diffuse transversally or laterally in the plane of the membrane?
They can only diffuse and rotate laterally
Is the lipid composition in the plasma membrane symmetrical or asymmetrical
asymmetrical
What side of the membrane are carbs on
extracellular
Are proteins embedded into the membrane symmetrically or asymmetrically
asymmetrically
Exocytosis
the exporting macromolecules from a cell by fusion of vesicles with the plasma membrane
What organelle is between a molecule and its final destination?
endoplasmic reticulum then the golgi apparatus then to lysosomes
How do transport vesicles work
the continually bud off from one compartment and fuse to another
, What directions can transport occur
in the forward direction by anterograde transportation or cisternal progression and also in the
reverse direction by retrograde transport
What cells use exocytosis
secretory cells to export products such as pancreas
Vesicle docking
once vesicle reaches target organelle it needs to dock with it in order to release its cargo. it must
correctly dock with its target protein
SNARE hypothesis
hypothesis to explain specificity of vesicle docking where vesicles display specific proteins on
their surface to identify their origin
Q SNAREs are complementary to
R SNAREs
What part of the organelle are cargo proteins delivered to
the lumen
How do botox work
they have a protease component that specifically cleaves its target SNARE in motor neurons
preventing neurotransmitter release causing flaccid paralysis
How does the tetanus toxin work
it uses proteases to cleave SNARES but in inhibitory neurons that regulate excitatory impulses
and therefore causes spastic paralysis
endocytosis
importing macromolecules into cell by forming vesicles from plasma membrane
Sphingolipids and sterols form
CORRECT ANSWERS!!
What is the continuous phase of the biological membrane
fluid lipid bilayer
What is the discontinuous phase in the plasma membrane
proteins floating in the lipids
What is the mosaic in the plasma membrane
made up of many different parts, proteins that interact with the lipid bilayer by electrostatic
interactions and proteins that span the membrane
Can lipids diffuse transversally or laterally in the plane of the membrane?
They can only diffuse and rotate laterally
Is the lipid composition in the plasma membrane symmetrical or asymmetrical
asymmetrical
What side of the membrane are carbs on
extracellular
Are proteins embedded into the membrane symmetrically or asymmetrically
asymmetrically
Exocytosis
the exporting macromolecules from a cell by fusion of vesicles with the plasma membrane
What organelle is between a molecule and its final destination?
endoplasmic reticulum then the golgi apparatus then to lysosomes
How do transport vesicles work
the continually bud off from one compartment and fuse to another
, What directions can transport occur
in the forward direction by anterograde transportation or cisternal progression and also in the
reverse direction by retrograde transport
What cells use exocytosis
secretory cells to export products such as pancreas
Vesicle docking
once vesicle reaches target organelle it needs to dock with it in order to release its cargo. it must
correctly dock with its target protein
SNARE hypothesis
hypothesis to explain specificity of vesicle docking where vesicles display specific proteins on
their surface to identify their origin
Q SNAREs are complementary to
R SNAREs
What part of the organelle are cargo proteins delivered to
the lumen
How do botox work
they have a protease component that specifically cleaves its target SNARE in motor neurons
preventing neurotransmitter release causing flaccid paralysis
How does the tetanus toxin work
it uses proteases to cleave SNARES but in inhibitory neurons that regulate excitatory impulses
and therefore causes spastic paralysis
endocytosis
importing macromolecules into cell by forming vesicles from plasma membrane
Sphingolipids and sterols form
