CELLULAR AND MOLECULAR BIOLOGY FINAL EXAM NEWEST 2024 ACTUAL EXAM 180 QUESTIONS AND
CORRECT DETAILED ANSWERS
In Eukaryotes, messenger RNA is synthesized by an enzyme called? - (answer) RNA polymerase II
The process of DNA replication requires that each of the parental DNA strands be used as a ____ to
produce a duplicate of the opposing strand. - (answer) Template
DNA replication is considered semi conservative because? - (answer) Each daughter DNA molecule
consists of one strand from the parent DNA molecule and one new strand
What does it mean for DNA replication to be bidirectional? - (answer) The replication forks formed at
the origin move in opposite directions
True or False? A strand of human chromosome was synthesized from multiple origins by a mixture of
continuous and discontinuous DNA synthesis. - (answer) True
The leading strand of DNA being formed is continuous, but the lagging strand forms a number of small
pieces of DNA. These are joined by enzymes called? - (answer) Ligases
DNA polymerases are processive, which means that they remain tightly associated with the template
strand while moving rapidly and adding nucleotides to the growing daughter strand. Which piece of the
replication machinery accounts for this characteristic? - (answer) Sliding clamp
Which of the following DNA strand can form a DNA duplex by pairing with itself at each position?
5'-AAGCCGAA-3'
5'-AAGCCGTT-3'
5'-AAGCGCAA-3'
5'-AAGCGCTT-3' - (answer) 5'-AAGCGCTT-3'
The information stored in the DNA sequence is used directly as a template to make ____. - (answer)
RNA
, CELLULAR AND MOLECULAR BIOLOGY FINAL EXAM NEWEST 2024 ACTUAL EXAM 180 QUESTIONS AND
CORRECT DETAILED ANSWERS
What type of macromolecule helps package DNA in a eukaryotic chromosomes? - (answer) Proteins
The DNA from two different species can often be distinguished by a difference in the ____. - (answer)
Ratio of A+T to G+C
Which of the following questions would not be answered by using karyotyping?
-Is the individual genetically female or male?
-Do any of the chromosomes contain pieces that belong to others chromosomes?
-does the individual have an extra chromosome?
- do any chromosomes contain point mutations? - (answer) Do any chromosomes contain point
mutations
The chromosomes we typically see in images are isolated from mitotic cells. These mitotic
chromosomes are in the most highly condensed form. Interphase cells contain chromosomes that are
less densely packed and ____. - (answer) Occupy discrete territories in the nucleus
The classic "beads on a string" structure is the most decondensed chromatin structure possible and is
produced experimentally. Which chromatin components are not retained when this structure is
generated? - (answer) Linker histones
Which of the following best describes the function of telomerase at the telomere?
- it adds new DNA to the 5' end of the newly synthesized strand at the telomere
- it adds new DNA to the 3' end of the newly synthesized strand at the telomere
- it synthesizes new DNA without the use of a template
- it adds new DNA to both strand of the telomere overhang - (answer) It adds new DNA to both strand
of the telomere overhang
The octameric histone core is composed of four different histone proteins, assembled in a stepwise
manner. Once the core octamer has been formed, DNA wraps around it to form a nucleosome core
particle. Which of the following histone proteins does not form part of the octameric core? - (answer)
H1
CORRECT DETAILED ANSWERS
In Eukaryotes, messenger RNA is synthesized by an enzyme called? - (answer) RNA polymerase II
The process of DNA replication requires that each of the parental DNA strands be used as a ____ to
produce a duplicate of the opposing strand. - (answer) Template
DNA replication is considered semi conservative because? - (answer) Each daughter DNA molecule
consists of one strand from the parent DNA molecule and one new strand
What does it mean for DNA replication to be bidirectional? - (answer) The replication forks formed at
the origin move in opposite directions
True or False? A strand of human chromosome was synthesized from multiple origins by a mixture of
continuous and discontinuous DNA synthesis. - (answer) True
The leading strand of DNA being formed is continuous, but the lagging strand forms a number of small
pieces of DNA. These are joined by enzymes called? - (answer) Ligases
DNA polymerases are processive, which means that they remain tightly associated with the template
strand while moving rapidly and adding nucleotides to the growing daughter strand. Which piece of the
replication machinery accounts for this characteristic? - (answer) Sliding clamp
Which of the following DNA strand can form a DNA duplex by pairing with itself at each position?
5'-AAGCCGAA-3'
5'-AAGCCGTT-3'
5'-AAGCGCAA-3'
5'-AAGCGCTT-3' - (answer) 5'-AAGCGCTT-3'
The information stored in the DNA sequence is used directly as a template to make ____. - (answer)
RNA
, CELLULAR AND MOLECULAR BIOLOGY FINAL EXAM NEWEST 2024 ACTUAL EXAM 180 QUESTIONS AND
CORRECT DETAILED ANSWERS
What type of macromolecule helps package DNA in a eukaryotic chromosomes? - (answer) Proteins
The DNA from two different species can often be distinguished by a difference in the ____. - (answer)
Ratio of A+T to G+C
Which of the following questions would not be answered by using karyotyping?
-Is the individual genetically female or male?
-Do any of the chromosomes contain pieces that belong to others chromosomes?
-does the individual have an extra chromosome?
- do any chromosomes contain point mutations? - (answer) Do any chromosomes contain point
mutations
The chromosomes we typically see in images are isolated from mitotic cells. These mitotic
chromosomes are in the most highly condensed form. Interphase cells contain chromosomes that are
less densely packed and ____. - (answer) Occupy discrete territories in the nucleus
The classic "beads on a string" structure is the most decondensed chromatin structure possible and is
produced experimentally. Which chromatin components are not retained when this structure is
generated? - (answer) Linker histones
Which of the following best describes the function of telomerase at the telomere?
- it adds new DNA to the 5' end of the newly synthesized strand at the telomere
- it adds new DNA to the 3' end of the newly synthesized strand at the telomere
- it synthesizes new DNA without the use of a template
- it adds new DNA to both strand of the telomere overhang - (answer) It adds new DNA to both strand
of the telomere overhang
The octameric histone core is composed of four different histone proteins, assembled in a stepwise
manner. Once the core octamer has been formed, DNA wraps around it to form a nucleosome core
particle. Which of the following histone proteins does not form part of the octameric core? - (answer)
H1
