Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen||ISBN NO:10,1975170555-Test Bank

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,3. The nurse is teaching a patient who will be discharged home with a prescription for an enteri
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c- coated tablet. Which statement by the patient indicates understanding of the teaching?
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a. I may crush the tablet and put it in applesauce to improve absorption.
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b. I should consume acidic foods to enhance absorption of this medication.
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c. I should expect a delay in onset of the drugs effects after taking the tablet.
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d. I should take this medication with high-
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fat foods to improve its action. ANS: C
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Enteric-
coated tablets resist disintegration in the acidic environment of the stomach and disintegrate
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when they reach the small intestine. There is usually some delay in onset of actions after takin
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g these medications. Enteric-
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coated tablets should not be crushed or chewed, which would alter the time and location of ab
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sorption. Acidic foods will not enhance the absorption of the medication. The patient should n
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ot to eat high-fat food before ingesting an enteric-coated tablet, because high-
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fat foods decrease the absorption rate.
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DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 T
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OP: NURSING PROCESS: Nursing Intervention
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
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x given by subcutaneous injection instead of by mouth. The nurse will explain that this is becau
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se
a. absorption is diminished by the first-pass effects in the liver.
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b. absorption is faster when insulin is given subcutaneously. xx xx xx xx xx xx xx



c. digestive enzymes in the gastrointestinal tract prevent absorption.
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d. the oral form is less predictable with more adverse effects
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. ANS: C
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Insulin, growth hormones, and other protein-
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based drugs are destroyed in the small intestine by digestive enzymes and must be given pare
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nterally. Because insulin is destroyed by digestive enzymes, it would not make it to the liver f
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or metabolism with a first-
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pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in such tissu
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e. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
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DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
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Pagex x 2x x ofx x 507

, TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
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MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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Pagex x 3x x ofx x 507