rr rr rr rr rr rr rr
rr TABLE OF CONTENT
rr rr
Chapterr r 1:r r Pharmacokinetics
Chapterrr2:rrDrug–
ReceptorrrInteractionsrrandrrPharmacodynamicsr r Chapterrr3:r r Ther
r AutonomicrrNervousrrSystem
Chapterrr4:rrCholinergicrrAgonistsrrC
hapterrr5:rrCholinergicrrAntagonistsrr
Chapterrr6:rrAdrenergicrrAgonistsrrCh
apterrr7:rrAdrenergicrrAntagonists
Chapterrr8:rrDrugsrrforrrNeurodegenerativerrDiseasesrrCh
apterrr9:rrAnxiolyticrrandrrHypnoticrrDrugs
Chapterrr10:rrAntidepressantsrrChapt
errr11:rrAntipsychoticrrDrugsrrChapte
rrr12:rrDrugsrrforrrEpilepsyrrChapterrr1
3:rrAnesthetics
Chapterr r 14:r r Opioids
Chapterrr15:rrDrugsrrofrrAbuserrChapt
errr16:rrCNSrrStimulantsrrChapterrr17:r
rAntihypertensivesrrChapterrr18:rr Diu
retics
Chapterr r 19:r r Heartr r Failure
Chapterrr20:rrAntiarrhythmicsrrChapt
errr21:rrAntianginalrrDrugs
Chapterrr22:rrAnticoagulantsrrandrrAntiplateletrrAgentsr r
Chapterrr23:rrDrugsrrforrrHyperlipidemia
Chapterrr24:rrPituitaryrrandrrThyroidrr
Chapterrr25:rrDrugsrrforrrDiabetes
Chapterrr26:rrEstrogensrrandrrAndrogensrrChapt
errr27:rrAdrenalrrHormones
Chapterr r 28:r r Drugsr r forr r Obesity
Chapterrr29:rrDrugsrrforrrDisordersrrofrrtherrRespiratoryrrSystemr r Chap
terrr30:rrAntihistamines
Chapterrr31:rrGastrointestinalrrandrrAntiemeticrrDrugsrrC
hapterrr32:rrDrugsrrforrrUrologicr r Disorders
Chapterr r 33:r r Drugsr r forr r Anemia
Chapterrr34:rrDrugsrrforrrDermatologicrrDisordersrrChapt
errr35:rrDrugsrrforrrBonerrDisorders
Chapterrr36:rrAnti-
inflammatory,rrAntipyretic,rrandr r AnalgesicrrAgentsr r Chapterrr37:r r Principle
srrofr r Antimicrobialr r Therapy
Chapterr r 38:r r Cellrr Wallr r Inhibitors
Chapterr r 39:r r Proteinr r Synthesisr r Inhibitors
Chapterrr40:rrQuinolones,rrFolicrrAcidr r Antagonists,r r andr r Urinaryr r TractrrAntisepticsrrCha
pterrr41:rrAntimycobacterialrrDrugs
Chapterrr42:rrAntifungalrrDrugsrrChap
terrr43:rrAntiprotozoalrrDrugsrrChapte
rrr44:rrAnthelminticrrDrugsrrChapterrr4
5:rrAntiviralrrDrugs
Chapterr r 46:r r Anticancerr r Drugs
Chapter 47: Immunosuppressants C
,
,
, 3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
rr coated tablet. Which statement by the patient indicates understanding of the teaching?
rr rr rr rr rr rr r r rr rr rr rr
a. I may crush the tablet and put it in applesauce to improve absorption.
rr rr rr rr rr rr rr rr rr rr rr rr
b. I should consume acidic foods to enhance absorption of this medication.
rr rr rr rr r rr rr rr rr rr
c. I should expect a delay in onset of the drugs effects after taking the tablet.
rr rr rr rr rr rr rr rr rr rr rr rr rr rr
d. I should take this medication with high-
rr rr rr rr rr rr
fat foods to improve its action. ANS: C
rr r rr rr rr rr rr
Enteric-
coated tablets resist disintegration in the acidic environment of the stomach and disintegrate whe
rr rr rr rr rr rr rr rr rr rr rr rr rr
n they reach the small intestine. There is usually some delay in onset of actions after taking these
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
medications. Enteric- rr
coated tablets should not be crushed or chewed, which would alter the time and location of absorpt
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
ion. Acidic foods will not enhance the absorption of the medication. The patient should not to eat
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
high-fat food before ingesting an enteric-coated tablet, because high-
rr rr rr rr rr rr rr rr
fat foods decrease the absorption rate.
rr rr rr rr rr
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TO
r rr rr rr rr rr rr rr
P: NURSING PROCESS: Nursing Intervention
rr rr rr rr
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
rr rr rr rr rr rr r
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be giv
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
en by subcutaneous injection instead of by mouth. The nurse will explain that this is because
rr rr rr rr rr rr rr rr rr rr r rr rr rr rr
a. absorption is diminished by the first-pass effects in the liver. rr rr rr rr rr rr rr rr rr
b. absorption is faster when insulin is given subcutaneously. rr rr rr rr rr rr rr
c. digestive enzymes in the gastrointestinal tract prevent absorption. rr rr rr rr r rr rr
d. the oral form is less predictable with more adverse effects.
rr rr r rr rr rr rr rr rr rr
ANS: C rr
Insulin, growth hormones, and other protein- rr rr rr rr rr
based drugs are destroyed in the small intestine by digestive enzymes and must be given parentera
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
lly. Because insulin is destroyed by digestive enzymes, it would not make it to the liver for metab
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
olism with a first- rr rr rr
pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in such tissue. In
rr rr rr rr rr rr rr rr rr rr rr rr rr rr rr
sulin is given subcutaneously because it is desirable to have it absorb slowly.
rr rr rr rr rr rr rr rr rr rr rr rr
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TO
rr rr rr rr rr rr rr rr
P: NURSING PROCESS: Nursing Intervention: Patient Teaching
rr rr rr rr rr rr
Pager r 2r r ofr r 507