1
BASIC SCIENCE-SUBCLAVIAN ARTERY REGIONAL
APPROACH AND MNEMONIC STUDY GUIDE TEST ACTUAL
TO REAL EXAM [2025-26]
1. Vertebral artery is a branch of which artery of the following? Subclavian artery
2. Which of the following statements regarding the subclavian vein
and its relations is correct?\ Anterior inferior to subclavian artery
Near apex of lung
3. Splenic flexure, sigmoid colon, until upper rectum blood supply?
Inferior mesenteric A
Superior mesenteric A
4. Genetic testing showed CFTR gene mutation with abnormal splicing. Which part
will RNA splicing remove?
Codon
introns
extons
5. 25 years old man presented at clinic with enlargement of breast and small firm
testes. No anosmia was noted. He is 1.9 m tall. Lab investigation showed
increase LH and FSH. Which is the most likely chromosome abnormality at this
patient?
46 XO
46 XX
47 XXY
47 XYY
Explanation : Klinefelter syndrome
6. A female patient with a Fragile X syndrome brother wondering about the
chances of being a carrier state?
<1%
100%
50%
25%
7. Most likely mode of inheritance of familial hypercholesterolemia? Autosomal
dominant
8. Man comes to clinic with a history of his father suffering from kidney disease
which was known to have multiple cyst at his kidney. What is the chance of this
,2
man of suffering from the disease?
100%
50%
33%
25%
0%
Explanation: (pastest) Adult onset polycystic kidney disease has an autosomal
dominant inheritance, hence many clinicians interchange the meaning of
ADPKD as autosomal dominant or adult polycystic kidney disease. Given that
this father will carry one gene for the disorder, he has a 50% chance of passing
it to any offspring. Around 85- 90% of pts with ADPKD carry a mutation on
chromosome 16, the remainder carrying a mutation on chromosome 4.
Significant renal failure usually develops after the 4th decade of life.
9. Center of temperature regulation? Hypothalamus
10. Study shows that with increasing age there is an increase in pulse pressure.
What is the cause of this ?
Reduce aortic compliance
Decrease diastolic heart function
11. Which one of the following features would be typical of a
mitochondrial disorder? Optic atrophy
Hypercholesterolae
mia Bronchiectasis
Pseudohypoparath
yroidism Spina
bifida
,3
12. Which tumor marker have best prognostic
value in seminoma? AFP
Beta HCG
LDH
13. Young girl with past history of hypersensitivity to egg allergy is noted. igE
towards eggs is elevated. Which of the following vaccine most likely to
produce an allergic reaction?
Hepatiti
sA
Influenz
a MMR
Tetanus
Varicell
a
14. 12 weeks pregnant women with no vaccination
history being tested : Varicella IgG (-)
Rubella IgG (-)
When should MMR vaccination should be given at
pregnant women? Now
18 weeks pregnant
24 weeks pregnant
26 weeks pregnant
Post partum
Explanation: “Women found to be seronegative on antenatal screening for
rubella should be offered an MMR (measles, mumps, rubella) vaccination
following birth and before discharge from the maternity unit if they are in
hospital.”
NICE guideline under immunization section.
https://www.nice.org.uk/guidance/cg37/chapte
r/1-recommendations
15. What will be broken down to
glucose and fructose? Maltose
Sucrose
Lactose
Explanatio
n:
, 4
16. Cytotoxic CD8 T cell? MHC class I
17. Which of the following produce IgE?
Mast cell
Plasma cell
18. Which of the following is the function of germinal
center at Lymph node? Maturation of dendritic cell
Generating inflammatory
response Antibody production
19. Patient presented with reccurent bacterial meningitis. What is the
deficient complement which involve alternative and classical pathway?
C1
C2
C7
MB
L
BASIC SCIENCE-SUBCLAVIAN ARTERY REGIONAL
APPROACH AND MNEMONIC STUDY GUIDE TEST ACTUAL
TO REAL EXAM [2025-26]
1. Vertebral artery is a branch of which artery of the following? Subclavian artery
2. Which of the following statements regarding the subclavian vein
and its relations is correct?\ Anterior inferior to subclavian artery
Near apex of lung
3. Splenic flexure, sigmoid colon, until upper rectum blood supply?
Inferior mesenteric A
Superior mesenteric A
4. Genetic testing showed CFTR gene mutation with abnormal splicing. Which part
will RNA splicing remove?
Codon
introns
extons
5. 25 years old man presented at clinic with enlargement of breast and small firm
testes. No anosmia was noted. He is 1.9 m tall. Lab investigation showed
increase LH and FSH. Which is the most likely chromosome abnormality at this
patient?
46 XO
46 XX
47 XXY
47 XYY
Explanation : Klinefelter syndrome
6. A female patient with a Fragile X syndrome brother wondering about the
chances of being a carrier state?
<1%
100%
50%
25%
7. Most likely mode of inheritance of familial hypercholesterolemia? Autosomal
dominant
8. Man comes to clinic with a history of his father suffering from kidney disease
which was known to have multiple cyst at his kidney. What is the chance of this
,2
man of suffering from the disease?
100%
50%
33%
25%
0%
Explanation: (pastest) Adult onset polycystic kidney disease has an autosomal
dominant inheritance, hence many clinicians interchange the meaning of
ADPKD as autosomal dominant or adult polycystic kidney disease. Given that
this father will carry one gene for the disorder, he has a 50% chance of passing
it to any offspring. Around 85- 90% of pts with ADPKD carry a mutation on
chromosome 16, the remainder carrying a mutation on chromosome 4.
Significant renal failure usually develops after the 4th decade of life.
9. Center of temperature regulation? Hypothalamus
10. Study shows that with increasing age there is an increase in pulse pressure.
What is the cause of this ?
Reduce aortic compliance
Decrease diastolic heart function
11. Which one of the following features would be typical of a
mitochondrial disorder? Optic atrophy
Hypercholesterolae
mia Bronchiectasis
Pseudohypoparath
yroidism Spina
bifida
,3
12. Which tumor marker have best prognostic
value in seminoma? AFP
Beta HCG
LDH
13. Young girl with past history of hypersensitivity to egg allergy is noted. igE
towards eggs is elevated. Which of the following vaccine most likely to
produce an allergic reaction?
Hepatiti
sA
Influenz
a MMR
Tetanus
Varicell
a
14. 12 weeks pregnant women with no vaccination
history being tested : Varicella IgG (-)
Rubella IgG (-)
When should MMR vaccination should be given at
pregnant women? Now
18 weeks pregnant
24 weeks pregnant
26 weeks pregnant
Post partum
Explanation: “Women found to be seronegative on antenatal screening for
rubella should be offered an MMR (measles, mumps, rubella) vaccination
following birth and before discharge from the maternity unit if they are in
hospital.”
NICE guideline under immunization section.
https://www.nice.org.uk/guidance/cg37/chapte
r/1-recommendations
15. What will be broken down to
glucose and fructose? Maltose
Sucrose
Lactose
Explanatio
n:
, 4
16. Cytotoxic CD8 T cell? MHC class I
17. Which of the following produce IgE?
Mast cell
Plasma cell
18. Which of the following is the function of germinal
center at Lymph node? Maturation of dendritic cell
Generating inflammatory
response Antibody production
19. Patient presented with reccurent bacterial meningitis. What is the
deficient complement which involve alternative and classical pathway?
C1
C2
C7
MB
L
