And CORRECT Answers
Multiple Sclerosis is an ___ mediated, progressive ___ disease of the CNS that results in
impaired ___ ____ - CORRECT ANSWERS immune, demyelinating, nerve transmission
MS affects - CORRECT ANSWERS 20-40 year old women
in MS, _ ___ remain in the CNS and promote ___ of other ___ that damage the immune system
and lead to ____ and ____ of the myelin and ___ formation - CORRECT ANSWERS T Cells,
infiltration, agents, inflammation, demyelination, plaque
most common form; with each relapse, recovery is complete but residual deficits accumulate
over time - CORRECT ANSWERS relapsing-remitting
disease progression with or without relapses - CORRECT ANSWERS secondary progressive
disabling symptoms steadily increase with rare plateaus and temporary improvement -
CORRECT ANSWERS primary progressive
least common; relapses with continuous disabling progression between exacerbations -
CORRECT ANSWERS progressive relapsing
diagnostic tests for MS (4) - CORRECT ANSWERS exam
MRI
EPS (evoked potential studies)
CSF (identifies presence of oligoclonal banding)
, disease-modifying meds - CORRECT ANSWERS A - Avonex (IM once per week) OR Rebif
(SQ 3 times per week)
B - Betaseron (SQ every other day)
C - Copaxone (SQ daily)
disease-modifying med goals (3) - CORRECT ANSWERS decrease frequency of relapse
decrease duration of relapse
decrease plaques on MRI
BRM side effects (5) - CORRECT ANSWERS flu-like - take at night
depression/suicidal tendencies/anxiety
leukopenia/thrombocytopenia
elevated liver enzymes
hypersensitivity at injection site
copaxone side effect - CORRECT ANSWERS transient chest pain
things to monitor when on BRMs (4) - CORRECT ANSWERS liver enzymes
CBC/platelets
injection site
emotional changes
cytoxan and methotrexate are ___ agents - CORRECT ANSWERS antineoplastic
immuran and sandimmune are ____ drugs - CORRECT ANSWERS immunosuppressant