Test Bank For Claytons Basic Pharmacology for Nurses 19th Edition By Michelle Willihnganz Samuel Gurevitz Bruce Clayton Chapter 1-48.

TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
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Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz:
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Clayton’sBasicPharmacologyforNurses,19thEdition
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MULTIPLECHOICE x




1. Whichnameidentifies adruglisted bythe USFood and Drug
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Administration (FDA)?
x x




a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: C x




The official name is the name under which a drug is listed by the
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FDA. The brand name, or trademark, is the name given to a drug
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by its manufacturer. The nonproprietary, or generic, name is
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provided by the United States Adopted Names Council.
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DIF: CognitiveLevel:Knowledge REF: p. 9 x x x x




OBJ: 1NAT: NCLEXClient Needs Category: Safe, Effective Care x x x x x x x x




Environment TOP: Nursing Process Step: Assessment
x CON: x x x x x




Patient Education
x x




2. Whichsourcecontainsinformation specificto nutritional supplements?
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a. USPDictionaryofUSAN &International DrugNames x x x x x x x




b. NaturalMedicinesComprehensiveDatabase x x x




c. UnitedStatesPharmacopoeia/NationalFormulary(USPNF) x x x x x




d. DrugInteractionFacts x x




ANS: C x




UnitedStatesPharmacopoeia/NationalFormularycontainsinformationspecifictonutritional
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supplements. USP Dictionary of USAN &International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-basedinformationonherbalmedicinesandherbalcombinationproducts;itdoesnot x x x x x x x x x x x




include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 x x x x x




NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x




TOP: NursingProcessStep: Assessment
x CON: Nutrition |Patient Education x x x x x x x




3. Whichdrugreference contains drugmonographs thatdescribe all drugs ina therapeutic class?
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a. DrugFactsandComparisons x x x




TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
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,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 2

b. DrugInteractionFacts x x




c. HandbookonInjectable Drugs x x x




d. Martindale—TheCompleteDrugReference x x x




ANS: A x




Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeuticclass.Monographsareformattedastablestoallowcomparison ofsimilar
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products, brand names, manufacturers, cost indices, and available dosage forms Online
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version is available.
x x x




DIF: CognitiveLevel: Knowledge REF: p. 4Table 1.2 x x x x x x




OBJ: 3 x NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
x x x x x x x




TOP: NursingProcessStep: Assessment
x CON: Safety|Patient Education |ClinicalJudgment x x x x x x x x x x




4. Whichdrugreference contains monographs about virtuallyeverysingle-entitydrugavailable in the
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United States and describes therapeutic uses of drugs, including approved and unapproved uses?
x x x x x x x x x x x x x




a. Martindale:TheCompleteDrugReference x x x x




b. AHFSDrugInformation x x




c. DrugReference x




d. DrugFactsandComparisons x x x




ANS: B x




AHFS Drug Information contains monographs about virtually every single-entity drug availablein
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theUnitedStatesanddescribes therapeuticusesofdrugs, includingapproved and unapproved uses.
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DIF: CognitiveLevel: Knowledge REF: p. 4Table 1.2 x x x x x x




OBJ: 3 x NAT: NCLEXClientNeedsCategory:PhysiologicalIntegrity
x x x x x x x




TOP: NursingProcess Step: Planning
x CON: Safety|Patient Education |ClinicalJudgment x x x x x x x x x x




5. Which online drug reference makes available to healthcare providers and the public a standard,
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comprehensive, up-to-datelookupanddownloadableresourceaboutmedicines?
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a. AmericanDrugIndex x x




b. AmericanHospitalFormulary x x




c. DailyMed
d. DrugReference x




ANS: C x




DailyMedmakes availabletohealthcareproviders and thepublicastandard,comprehensive, up-
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to-datelookupanddownloadableresourceabout medicines.TheAmericanDrugIndexis not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
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The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 x x x x x x x OBJ:3 x




NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x




TOP: NursingProcessStep: Implementation
x x x x




CON: Safety|PatientEducation |ClinicalJudgment
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6. WhichlegislationauthorizestheFDAto determinethesafetyof adrugbeforeitsmarketing?
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a. FederalFood,Drug,and CosmeticAct(1938) x x x x x x




b. DurhamHumphreyAmendment (1952) x x x




TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
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,TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 3

c. ControlledSubstancesAct(1970) x x x




d. KefauverHarrisDrugAmendment(1962) x x x x




ANS: A x




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all
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drugs before marketing. Later amendments and acts helped tighten FDA control and ensure drug
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safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used safely
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without medical supervision and restricts their sale to prescription by a licensedpractitioner.The
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ControlledSubstancesActaddressesonlycontrolledsubstancesand theircategorization. The
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Kefauver HarrisDrug Amendmentensures drug efficacyand greater drug safety. Drug
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manufacturers are required to prove to the FDA the effectiveness of their products before marketing
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them.
x




DIF: CognitiveLevel: Knowledge REF: p. 5Table l.3 x x x x x x




OBJ: 5 x NAT:NCLEXClient NeedsCategory: Physiological Integrity x x x x x x




TOP: Nursing Process Step: Assessment
x x x x x




CON: Safety|Patient Education |Evidence |Health Care Law
x x x x x x x x x x




7. Whichclassificationdoesmeperidine(Demerol)fallunder?
x x x x x x




a. I
b. II
c. III
d. IV
ANS: B x




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe
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psychological and physicaldependence.ScheduleIdrugs havehigh potentialforabuse and no
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recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
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moderate physical dependence or high psychological dependence. Schedule IV drugs have low
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potential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ:2 x x x x x




NAT: NCLEXClient NeedsCategory: Safe,EffectiveCareEnvironment
x x x x x x x x x




TOP: NursingProcessStep: Assessment
x CON: Patient Education |Addiction|Pain x x x x x x x x x




8. Whichaction wouldtheFDAtaketoexpeditedrugdevelopment and approvalforan outbreak of
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smallpox?
x




a. Listsmallpox asahealth orphandisease.x x x x x x




b. Omitthepreclinical researchphase. x x x x




c. Extendtheclinicalresearchphase. x x x x




d. Fasttracktheinvestigationaldrug. x x x x




ANS: D x




Once the Investigational New Drug Application has been approved, the drug can receive highest
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priority within the agency, which is called fast tracking. A smallpox outbreak would become a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
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research is not omitted. Extending anyphase of the research would mean alongertimeto develop a
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vaccine.TheFDAmust ensurethatall phasesof thepreclinical and clinical research phase have been
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completed in a safe manner.
x x x x x




DIF: CognitiveLevel: Knowledge x x REF: p. 7 x x x OBJ: 5 x




TestBank ForClayton’s BasicPharmacology forNurses 19thEdition
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, TestBank For Clayton’sBasic PharmacologyforNurses19thEdition
x x x x x x x x x 4

NAT: NCLEX Client Needs Category:Safe, Effective Care Environment
x x x x x x x x




TOP: Nursing Process Step: Assessment
x x x x x




CON: HealthCareLaw|Health CarePolicy |Infection |CareCoordination
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9. Whichstatement is trueabout over-the-counter(OTC) drugs?
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a. Theyare not listed in theUSPNF. x x x x x x x




b. Aprescription froma healthcareprovideris needed.
x x x x x x x




c. Theyaresoldwithoutaprescription. x x x x x




d. Theyareknown onlybytheir brand names. x x x x x x x




ANS: C x




OTC medications do not require a prescription. A variety of names, both generic and trade, canbe
x x x x x x x x x x x x x x x x




used forindividualdrugssold OTC.OTC drugsarelistedintheUSPNF. Prescription drugs require an
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order by a health professional who is licensed to prescribe, such as a physician, nurse practitioner,
x x x x x x x x x x x x x x x x




physician assistant, or dentist.
x x x x




DIF: Cognitive Level: Comprehension REF: p. 2 OBJ:2 x x x x x




NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x




TOP: NursingProcess Step: Planning
x CON: PatientEducation x x x x x




10. Whichisthemost authoritativereferenceformedicationsthatareinjected?
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a. Martindale:TheComplete x x




b. HandbookonInjectable Drugs x x x




c. DailyMed
d. HandbookofNonprescriptionDrugs x x x




ANS: B x




The Handbook on Injectable Drugs is the most comprehensive reference available on the topicof
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compatibilityofinjectabledrugs. Itisacollection ofmonographs formorethan300 injectable drugs
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that are listed alphabetically by generic name.
x x x x x x x




DIF: Cognitive Level: Knowledge REF: p. 4 OBJ:3 x x x x x




NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x




TOP: NursingProcessStep: Assessment
x CON: ClinicalJudgment |Safety x x x x x x x




11. Whichstatementistrueabout Lomotil? x x x x x




a. Abusepotential forthisdrugis low. x x x x x x




b. Psychologicaldependencyislikely. x x x




c. Thereis ahigh potential forabuse. x x x x x x




d. This drugis not acontrolled substance. x x x x x x




ANS: A x




Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological dependence
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liabilitycomparedwithdrugsinSchedule IV. Becauseabusepotentialislow with aSchedule Vdrug, a
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prescription maynot be required. Psychological dependencyisnot likely with a Schedule V drug.
x x x x x x x x x x x x x x x




Schedule V drugs are classified as controlled substances.
x x x x x x x x




DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ:2 x x x x x x x




NAT: NCLEX Client Needs Category: Physiological Integrity
x x x x x x x




TOP: NursingProcessStep: Assessment
x CON: ClinicalJudgment |Safety |PatientEducation x x x x x x x x x x