Clinical Pharmacology High Yield for MCCQE1 UPDATED ACTUAL Exam Questions and CORRECT Answers

Clinical Pharmacology High Yield for
MCCQE1 UPDATED ACTUAL Exam
Questions and CORRECT Answers
Beta-blockers - CORRECT ANSWER - Block β-adrenergic receptors → ↓ HR, ↓ BP



ACE inhibitors - CORRECT ANSWER - Block conversion of Ang I → Ang II →
vasodilation


ARBs - CORRECT ANSWER - Block Ang II receptor directly



Vasodilation (arteries) - CORRECT ANSWER - Amlodipine, nifedipine



CCBs (dihydropyridine) - CORRECT ANSWER - ↓ HR, ↓ AV nodal conduction



CCBs (non-dihydropyridine) - CORRECT ANSWER - Diltiazem, verapamil



Statins - CORRECT ANSWER - Inhibit HMG-CoA reductase → ↓ cholesterol



PPIs - CORRECT ANSWER - Irreversible H+/K+ ATPase inhibitor



Anticoagulants - CORRECT ANSWER - Prevent clot formation



ACE inhibitors - CORRECT ANSWER - Cough, angioedema, hyperkalemia



Statins - CORRECT ANSWER - Myopathy, ↑ LFTs

, Aminoglycosides - CORRECT ANSWER - Nephrotoxicity, ototoxicity



Lithium - CORRECT ANSWER - Hypothyroidism, nephrogenic diabetes insipidus,
tremor


Amiodarone - CORRECT ANSWER - Thyroid dysfunction, pulmonary fibrosis, liver
toxicity


Digoxin - CORRECT ANSWER - Visual disturbances (yellow halos), arrhythmias



Methotrexate - CORRECT ANSWER - Myelosuppression, hepatotoxicity, pulmonary
toxicity


Cisplatin - CORRECT ANSWER - Nephrotoxicity, ototoxicity



CAP outpatient - CORRECT ANSWER - Amoxicillin ± azithromycin



CAP inpatient - CORRECT ANSWER - Ceftriaxone + azithromycin



Meningitis (adult) - CORRECT ANSWER - Ceftriaxone + vancomycin ± ampicillin



UTI uncomplicated - CORRECT ANSWER - Nitrofurantoin or TMP-SMX



Sepsis - CORRECT ANSWER - Piperacillin-tazobactam + vancomycin



Vancomycin - CORRECT ANSWER - Red man syndrome, nephrotoxicity



Aminoglycosides (gentamicin) - CORRECT ANSWER - Nephrotoxicity, ototoxicity