MT (AAB) Hematology || Answered Perfectly 100%.
What is hemoglobin composed of? correct answers 4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? correct answers porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood cell?
correct answers to keep iron in the ferrous state
Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen? correct answers carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? correct
answers methemoglobin
Which hemoglobin derivative causes irreversible changes in teh red blood cells? correct answers
sulfhemoglobin
Which of the following hemoglobins is NOT normally present in a normal adult correct answers
Hb-S
Which embryonic hemoglobin is normally found in newborns correct answers Hb-F
What is the most abundant hemoglobin in a newborn? correct answers Hb-F
What is the molecular structure of hemoglobin S? correct answers Valine replaces glutamic acid
in the 6th position of the beta chain
,Which of the following hemoglobins is insoluble under lowered oxygen tensions? correct
answers Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia correct
answers hemoglobin electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule? correct answers sodium dithionite
In hemoglobin C, what replaces glutamic acid? correct answers lysine
Which RBC inclusion is characteristic of hemoglobin C disease? correct answers rod-shaped
crystals
What is hemoglobin F composed o? correct answers 2 alpha + 2 gamma chains
Which hemoglobin is resistant to alkali denaturation correct answers Hb-F
What hemoglobin's are differentiated by the Kleihauer-Betke technique correct answers Hd-A1
from Hb-F
What is the order of migration of hemoglobins, from fastest to slowest, on cellulose acetate at pH
8.4 correct answers A1, F, S,C
Why is citrate agar used when abnormal hemoglobins are identified on cellulose acetate at pH
8.6? correct answers It seperates hemoglobin S from hemoglobin D
The cyanmethemoglobin method measures all hemoglobin pigments EXCEPT which one?
correct answers sulfhemoglobin
, What is the diluent in the cyanmethhemoglobin method for the determination of hemoglobin?
correct answers Drabkin's solution
What is the normal plasma hemoglobin concentration? correct answers 2-3 mg/dL
Which plasma protein binds free hemoglobin correct answers haptoglobin
Which one of the following statements concerning hemolytic anemia is false? correct answers
The serum haptoglobin is increased
Myoglobin can be separated from hemoglobin by saturating the specimen with which one of the
following reagents? correct answers ammonium sulfate
The hematocrit is also know as which one of the following terms? correct answers packed RBC
volume
The degree of packing of cells during centrifugation depends on all of the following EXCEPT
which one? correct answers bore size of the microhematocrit tube
During examination of a spun hematocrit, in which layer are the WBC's found? correct answers
buffy coat
When performing a microhematocrit, where should one read the percentage of packed RBC
column from a microhematocrit reading device? correct answers below the buffy coat
An increase in the erythrocyte sedimentation rate can be the result of an increase in the quantity
of which of the following? correct answers fibrinogen
Which test is increased in acute infections? correct answers erythrocyte sedimentation rate
What is hemoglobin composed of? correct answers 4 heme, 4 iron, 4 globins
What disorder does a defect in heme synthesis lead to? correct answers porphyria
What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood cell?
correct answers to keep iron in the ferrous state
Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than
oxygen? correct answers carboxyhemoglobin
What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? correct
answers methemoglobin
Which hemoglobin derivative causes irreversible changes in teh red blood cells? correct answers
sulfhemoglobin
Which of the following hemoglobins is NOT normally present in a normal adult correct answers
Hb-S
Which embryonic hemoglobin is normally found in newborns correct answers Hb-F
What is the most abundant hemoglobin in a newborn? correct answers Hb-F
What is the molecular structure of hemoglobin S? correct answers Valine replaces glutamic acid
in the 6th position of the beta chain
,Which of the following hemoglobins is insoluble under lowered oxygen tensions? correct
answers Hb-S
What laboratory test is used to confirm the specific diagnosis of sickle cell anemia correct
answers hemoglobin electrophoresis
In the solubility test for hemoglobin S, what is the reagent responsible for the reduction of the
hemoglobin molecule? correct answers sodium dithionite
In hemoglobin C, what replaces glutamic acid? correct answers lysine
Which RBC inclusion is characteristic of hemoglobin C disease? correct answers rod-shaped
crystals
What is hemoglobin F composed o? correct answers 2 alpha + 2 gamma chains
Which hemoglobin is resistant to alkali denaturation correct answers Hb-F
What hemoglobin's are differentiated by the Kleihauer-Betke technique correct answers Hd-A1
from Hb-F
What is the order of migration of hemoglobins, from fastest to slowest, on cellulose acetate at pH
8.4 correct answers A1, F, S,C
Why is citrate agar used when abnormal hemoglobins are identified on cellulose acetate at pH
8.6? correct answers It seperates hemoglobin S from hemoglobin D
The cyanmethemoglobin method measures all hemoglobin pigments EXCEPT which one?
correct answers sulfhemoglobin
, What is the diluent in the cyanmethhemoglobin method for the determination of hemoglobin?
correct answers Drabkin's solution
What is the normal plasma hemoglobin concentration? correct answers 2-3 mg/dL
Which plasma protein binds free hemoglobin correct answers haptoglobin
Which one of the following statements concerning hemolytic anemia is false? correct answers
The serum haptoglobin is increased
Myoglobin can be separated from hemoglobin by saturating the specimen with which one of the
following reagents? correct answers ammonium sulfate
The hematocrit is also know as which one of the following terms? correct answers packed RBC
volume
The degree of packing of cells during centrifugation depends on all of the following EXCEPT
which one? correct answers bore size of the microhematocrit tube
During examination of a spun hematocrit, in which layer are the WBC's found? correct answers
buffy coat
When performing a microhematocrit, where should one read the percentage of packed RBC
column from a microhematocrit reading device? correct answers below the buffy coat
An increase in the erythrocyte sedimentation rate can be the result of an increase in the quantity
of which of the following? correct answers fibrinogen
Which test is increased in acute infections? correct answers erythrocyte sedimentation rate
