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Illustrated Reviews: Pharmacology 8th
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Edition by Karen Whalen u u u
COMPLETE CHAPTERS 1- u u
48 WITH RATIONALES|A+ GRADED
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100% EXPERT VERIFIED Q&As
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, 3. Theunurseuisuteachinguaupatientuwhouwillubeudischargeduhomeuwithuauprescriptionuforuanuenteric-
ucoatedutablet.uWhichustatementubyutheupatientuindicatesuunderstandinguofutheuteaching?
a. Iumayucrushutheutabletuanduputuituinuapplesauceutouimproveuabsorption.
b. Iushoulduconsumeuacidicufoodsutouenhanceuabsorptionuofuthisumedication.
c. Iushoulduexpectuaudelayuinuonsetuofutheudrugsueffectsuafterutakingutheutablet.
d. Iushouldutakeuthisumedicationuwithuhigh-fatufoodsutouimproveuitsuaction.uCORRECTuANSWER:uC
Enteric-
coatedutabletsuresistudisintegrationuinutheuacidicuenvironmentuofutheustomachuandudisintegrateuwhenutheyurea
chutheusmalluintestine.uThereuisuusuallyusomeudelayuinuonsetuofuactionsuafterutakingutheseumedications.uEnteri
c-
coatedutabletsushouldunotubeucrusheduoruchewed,uwhichuwouldualterutheutimeuandulocationuofuabsorption.uAci
dicufoodsuwillunotuenhanceutheuabsorptionuofutheumedication.uTheupatientushouldunotutoueatuhigh-
fatufoodubeforeuingestinguanuenteric-coatedutablet,ubecauseuhigh-fatufoodsudecreaseutheuabsorptionurate.
DIF:uCOGNITIVEuLEVEL:uApplyingu(Application)uREF:udmu3uTOP:uNURSINGuPROCESS:uNursinguInte
rvention
MSC:uNCLEX:uPhysiologicaluIntegrity:uPharmacologicaluanduParenteraluTherapies
4. Aupatientuwhouisunewlyudiagnoseduwithutypeu1udiabetesumellitusuasksuwhyuinsulinumustubeugivenubyus
ubcutaneousuinjectionuinsteaduofubyumouth.uTheunurseuwilluexplainuthatuthisuisubecause
a. absorptionuisudiminishedubyutheufirst-passueffectsuinutheuliver.
b. absorptionuisufasteruwhenuinsulinuisugivenusubcutaneously.
c. digestiveuenzymesuinutheugastrointestinalutractupreventuabsorption.
d. theuoraluformuisulessupredictableuwithumoreuadverseueffects.uCORRECTuANSWER:uC
Insulin,ugrowthuhormones,uanduotheruprotein-
basedudrugsuareudestroyeduinutheusmalluintestineubyudigestiveuenzymesuandumustubeugivenuparenterally.uBeca
useuinsulinuisudestroyedubyudigestiveuenzymes,uituwouldunotumakeuitutoutheuliveruforumetabolismuwithuaufirst-
passueffect.uSubcutaneousutissueuhasufewerublooduvessels,usouabsorptionuisusloweruinusuchutissue.uInsulinuisu
givenusubcutaneouslyubecauseuituisudesirableutouhaveuituabsorbuslowly.
DIF:uCOGNITIVEuLEVEL:uUnderstandingu(Comprehension)uREF:udmu3uTOP:uNURSINGuPROCESS:uNur
singuIntervention:uPatientuTeaching
MSC:uNCLEX:uPhysiologicaluIntegrity:uPharmacologicaluanduParenteraluTherapies
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