Understanding u
Pathophysiology,
6th Edition Huether &
u u u u
McCance Test Bank.
u u
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
Chapter 01: Cellular Biology
u u u
Huether & McCance: Understanding Pathophysiology, 6th Edition
u u u u u u
MULTIPLEuCHOICE
1. Austudentuisuobservinguaucelluunderutheumicroscope.uItuisuobservedutouhaveusupercoileduDNAu
withuhistones.uWhichuofutheufollowinguwouldualsoubeuobservedubyutheustudent?
a. Ausingleucircularuchromosome
b. Aunucleus
c. Free-floatingunuclearumaterial
d. Nouorganelles
ANS:u B
Theucelludescribeduisuaueukaryoticucell,usouituhasuhistonesuanduausupercoileduDNAuwithinuitsunucle
us;uthus,utheunucleusushouldubeuobserved.uAusingleucircularuchromosomeucalleduauprokaryoteuco
ntainsufree-floatingunuclearumaterialubutuhasunouorganelles.
REF:u p.u2
2. Aunurseuisuinstructingutheustaffuaboutucellularufunctions.uWhichucellularufunctionuisutheunurseud
escribinguwhenuanuisolateducelluabsorbsuoxygenuanduusesuitutoutransformunutrientsutouenergy?
a. Metabolicuabsorption
b. Communication
c. Secretion
d. Respiration
ANS:u D
Theucell’suabilityutouabsorbuoxygenuisureferredutouasurespirationuwhileuitsucommunicationuabilityuinv
olvesumaintenanceuofuausteadyudynamicustate,umetabolicuabsorptionuprovidesunutrition,uandusecreti
onuallowsuforutheusynthesizinguofunewusubstances.
REF:u p.u2
3. AueukaryoticucelluisuundergoinguDNAureplication.uInuwhichuregionuofutheucelluwouldumostuofut
heugeneticuinformationubeucontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusuCytoplasm
ANS:u C
Theuregionuofutheucelluthatucontainsugeneticumaterial,uincludinguaulargeuamountuofuribonucleicuac
id,umostuofutheuDNA,uanduDNA-
bindinguproteins,uisutheunucleolus,uwhichuisulocateduwithinutheucell’sunucleus.uMitochondriauisua
ssociateduwithucellularurespiration,uwhileuribosomesuareuinvolveduwithuproteinumanufacturing.u
Cytoplasmuisuaufluidufillinguthatuisuaucomponentuofutheucell.
REF:u p.u2
NURSINGTB.COM
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
4. Whichuofutheufollowingucanuremoveuproteinsuattachedutoutheucell’subilayerubyudissolvingutheul
ayeruitself?
a. Peripheralumembraneuproteins
b. Integralumembraneuproteins
c. Glycoproteins
d. Celluadhesionumolecules
ANS:u B
Proteinsudirectlyuattachedutoutheumembraneubilayerucanubeuremovedubyutheuactionuofuintegralume
mbraneuproteinsuthatudissolveutheubilayer.uPeripheralumembraneuproteinsuresideuatutheusurfaceuw
hileucelluadhesionumoleculesuareuonutheuoutsideuofutheumembrane.uGlycoproteinumarksucellsuand
udoesunotufloat.
REF:u p.u7
5. Whichuofutheufollowingucanubindutouplasmaumembraneureceptors?
a. Oxygen
b. Ribosomes
c. Amphipathiculipids
d. Ligands
ANS:u D
Ligandsuareutheuonlyuspecificumoleculesuthatucanubinduwithureceptorsuonutheucellumembrane.
REF:u p.u9
6. Aunurseuisureviewinguaureportufromuaupatientuwithumetastaticucancer.uWhatualternationuinuthe
a. Decreasedufibronectin
b. Increaseducollagen
c. Decreaseduelastin
d. Increaseduglycoproteins
ANS:u A
Onlyuaureduceduamountuofufibronectinuisufounduinusomeutypesuofucancerousucells,uallowinguthemu
toutraveluorumetastasize.
REF:u p.u10
7. Whichuformuofucellucommunicationuisuusedutourelateutouotherucellsuinudirectuphysicalucontact?
a. Cellujunction
b. Gapujunction
c. Desmosome
d. Tightujunction
ANS:u A
Cellujunctionsuholducellsutogetheruandupermitumoleculesutoupassufromucellutoucell.
Gapujunctionsuallowuforucellularucommunicationubetweenucells.uNeitherudesmosomesunorutightujunc
tionsuareuassociateduwithucellularucommunication.
REF:u p.u11
NURSINGTB.COM
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
8. Pancreaticubetaucellsusecreteuinsulin,uwhichuinhibitsusecretionuofuglucagonufromuneighboringua
lphaucells.uThisuactionuisuanuexampleuofuwhichuofutheufollowingusignalingutypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:u A
Paracrineusignalinguinvolvesutheureleaseuofulocaluchemicalumediatorsuthatuareuquicklyutakenuup,udest
royed,uoruimmobilized,uasuinutheucaseuofuinsulinuandutheuinhibitionuofutheusecretionuofuglucagon.uNo
neuofutheuotheruoptionsuinvolveusignalinguthatuisuassociateduwithuaulocaluchemicalumediatorulikeuins
ulin.
REF:u p.u12
9. Inucellularumetabolism,ueachuenzymeuhasuauhighuaffinityuforua:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:u B
Eachuenzymeuhasuauhighuaffinityuforuausubstrate,uauspecificusubstanceuconvertedutouauproductuofuth
eureaction.uCellularumetabolismuisunotudependentuonuanuattractionubetweenuanuenzymeuanduanyuo
futheuremaininguoptions.
REF:uuup.u16
NURSINGTB.COM
10. Anuathleteurunsuaumarathon,uafteruwhichuhisumusclesufeelufatigueduanduunableutoucontract.uTheuat
hleteuasksutheunurseuwhyuthisuhappened.uTheunurse’suresponseuisubaseduonutheuknowledgeuthatutheu
problemuisuresultuofuaudeficiencyuof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:u C
WhenuATPuisudeficient,uimpairedumuscleucontractionuresults.uNoneuofutheuotheruoptionsuareuinvolv
eduinumuscleucontraction.
REF:u p.u16
11. WhichuphaseuofucatabolismuproducesutheumostuATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricuaciducycle
ANS:u D
WhileusomeuATPuisuproduceduduringutheuoxidationuanduglycolysisuphases,umostuofutheuATPuisug
enerateduduringutheucitricuaciducycle.uDigestionudoesunotuproduceuanyuATP.
NURSINGTB.COM
Pathophysiology,
6th Edition Huether &
u u u u
McCance Test Bank.
u u
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
Chapter 01: Cellular Biology
u u u
Huether & McCance: Understanding Pathophysiology, 6th Edition
u u u u u u
MULTIPLEuCHOICE
1. Austudentuisuobservinguaucelluunderutheumicroscope.uItuisuobservedutouhaveusupercoileduDNAu
withuhistones.uWhichuofutheufollowinguwouldualsoubeuobservedubyutheustudent?
a. Ausingleucircularuchromosome
b. Aunucleus
c. Free-floatingunuclearumaterial
d. Nouorganelles
ANS:u B
Theucelludescribeduisuaueukaryoticucell,usouituhasuhistonesuanduausupercoileduDNAuwithinuitsunucle
us;uthus,utheunucleusushouldubeuobserved.uAusingleucircularuchromosomeucalleduauprokaryoteuco
ntainsufree-floatingunuclearumaterialubutuhasunouorganelles.
REF:u p.u2
2. Aunurseuisuinstructingutheustaffuaboutucellularufunctions.uWhichucellularufunctionuisutheunurseud
escribinguwhenuanuisolateducelluabsorbsuoxygenuanduusesuitutoutransformunutrientsutouenergy?
a. Metabolicuabsorption
b. Communication
c. Secretion
d. Respiration
ANS:u D
Theucell’suabilityutouabsorbuoxygenuisureferredutouasurespirationuwhileuitsucommunicationuabilityuinv
olvesumaintenanceuofuausteadyudynamicustate,umetabolicuabsorptionuprovidesunutrition,uandusecreti
onuallowsuforutheusynthesizinguofunewusubstances.
REF:u p.u2
3. AueukaryoticucelluisuundergoinguDNAureplication.uInuwhichuregionuofutheucelluwouldumostuofut
heugeneticuinformationubeucontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusuCytoplasm
ANS:u C
Theuregionuofutheucelluthatucontainsugeneticumaterial,uincludinguaulargeuamountuofuribonucleicuac
id,umostuofutheuDNA,uanduDNA-
bindinguproteins,uisutheunucleolus,uwhichuisulocateduwithinutheucell’sunucleus.uMitochondriauisua
ssociateduwithucellularurespiration,uwhileuribosomesuareuinvolveduwithuproteinumanufacturing.u
Cytoplasmuisuaufluidufillinguthatuisuaucomponentuofutheucell.
REF:u p.u2
NURSINGTB.COM
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
4. Whichuofutheufollowingucanuremoveuproteinsuattachedutoutheucell’subilayerubyudissolvingutheul
ayeruitself?
a. Peripheralumembraneuproteins
b. Integralumembraneuproteins
c. Glycoproteins
d. Celluadhesionumolecules
ANS:u B
Proteinsudirectlyuattachedutoutheumembraneubilayerucanubeuremovedubyutheuactionuofuintegralume
mbraneuproteinsuthatudissolveutheubilayer.uPeripheralumembraneuproteinsuresideuatutheusurfaceuw
hileucelluadhesionumoleculesuareuonutheuoutsideuofutheumembrane.uGlycoproteinumarksucellsuand
udoesunotufloat.
REF:u p.u7
5. Whichuofutheufollowingucanubindutouplasmaumembraneureceptors?
a. Oxygen
b. Ribosomes
c. Amphipathiculipids
d. Ligands
ANS:u D
Ligandsuareutheuonlyuspecificumoleculesuthatucanubinduwithureceptorsuonutheucellumembrane.
REF:u p.u9
6. Aunurseuisureviewinguaureportufromuaupatientuwithumetastaticucancer.uWhatualternationuinuthe
a. Decreasedufibronectin
b. Increaseducollagen
c. Decreaseduelastin
d. Increaseduglycoproteins
ANS:u A
Onlyuaureduceduamountuofufibronectinuisufounduinusomeutypesuofucancerousucells,uallowinguthemu
toutraveluorumetastasize.
REF:u p.u10
7. Whichuformuofucellucommunicationuisuusedutourelateutouotherucellsuinudirectuphysicalucontact?
a. Cellujunction
b. Gapujunction
c. Desmosome
d. Tightujunction
ANS:u A
Cellujunctionsuholducellsutogetheruandupermitumoleculesutoupassufromucellutoucell.
Gapujunctionsuallowuforucellularucommunicationubetweenucells.uNeitherudesmosomesunorutightujunc
tionsuareuassociateduwithucellularucommunication.
REF:u p.u11
NURSINGTB.COM
, UnderstandinguPathophysiologyu6thuEditionuHuetheruTestuBank
8. Pancreaticubetaucellsusecreteuinsulin,uwhichuinhibitsusecretionuofuglucagonufromuneighboringua
lphaucells.uThisuactionuisuanuexampleuofuwhichuofutheufollowingusignalingutypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:u A
Paracrineusignalinguinvolvesutheureleaseuofulocaluchemicalumediatorsuthatuareuquicklyutakenuup,udest
royed,uoruimmobilized,uasuinutheucaseuofuinsulinuandutheuinhibitionuofutheusecretionuofuglucagon.uNo
neuofutheuotheruoptionsuinvolveusignalinguthatuisuassociateduwithuaulocaluchemicalumediatorulikeuins
ulin.
REF:u p.u12
9. Inucellularumetabolism,ueachuenzymeuhasuauhighuaffinityuforua:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:u B
Eachuenzymeuhasuauhighuaffinityuforuausubstrate,uauspecificusubstanceuconvertedutouauproductuofuth
eureaction.uCellularumetabolismuisunotudependentuonuanuattractionubetweenuanuenzymeuanduanyuo
futheuremaininguoptions.
REF:uuup.u16
NURSINGTB.COM
10. Anuathleteurunsuaumarathon,uafteruwhichuhisumusclesufeelufatigueduanduunableutoucontract.uTheuat
hleteuasksutheunurseuwhyuthisuhappened.uTheunurse’suresponseuisubaseduonutheuknowledgeuthatutheu
problemuisuresultuofuaudeficiencyuof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:u C
WhenuATPuisudeficient,uimpairedumuscleucontractionuresults.uNoneuofutheuotheruoptionsuareuinvolv
eduinumuscleucontraction.
REF:u p.u16
11. WhichuphaseuofucatabolismuproducesutheumostuATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricuaciducycle
ANS:u D
WhileusomeuATPuisuproduceduduringutheuoxidationuanduglycolysisuphases,umostuofutheuATPuisug
enerateduduringutheucitricuaciducycle.uDigestionudoesunotuproduceuanyuATP.
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