Pharmacology Specialty Medications
Final Exam with Revised Complete
Solutions 2025.
Initial medication for RA before special - Answer DMARD (Disease modifying antirheumatic
drug)
not always effective
Recent hepatitis C treatment time - Answer 3 months; 96% cure rate
HIV/AIDS virus destroys __ cells/immune system while pt asymptomatic - Answer CD4/T cells
Recombinant DNA technology - Answer joining 2 DNA molecules & inserting into a host
organism and generates products from human use
Biologics - Answer specialty meds made from recombinant DNA technology; growth of
specialty pharmacy industry.
Humoral immunity - Answer immune response from B-cells + antibody production
Leukocytes that develop plasma cells & produce antibodies to bind to antigens - Answer B-
cells
Antibodies - Answer molecules that bind/inactivate antigen molecules via formation of
antigen-antibody complex
immune response mediated by T cells/lymphocytes; collab w/humoral immunity - Answer cell-
mediated immunity
___ produces cytokines - Answer T cells
Nonantibody proteins released by activated t cells upon contact w antigens. intercellular
, cells limit immune response/balances helper T cells - Answer T suppressor
differentiated T cells that recognizes foreign antigens/destroys target cell - Answer Cytotoxic T
cells
biologics that enhance/reduce immune response - Answer immunomodulating drugs
immunomodulating drugs example - Answer interferons, monoclonal antibodies, interleukin
receptor antagonists/agonists, miscellaneous drugs.
___ drugs specifically treat cancer cells/avoids healthy cells and treats autoimmune
inflammatory dz/RA; interferes w overactive immune response. - Answer immunomodulating
drugs
proteins w antitumor, antiviral, immunomodulating properties; tx cancer/viral infections -
Answer interferons
interferons affects on immune system - Answer restore/augment/inhibit function
interferon beta-1a drug; tx MS/slows progression physical disability - Answer Avonex or Rebif;
s/e- flu like symptoms.
___ once weekly IM (interferon beta-1a) - Answer Avonex
___ 3x/week SUBQ (interferon beta-1a) - Answer Rebif
costly drugs created w recombinant DNA that specifically target cancer cells and treat
RA/chron's/MS/organ tx - Answer monoclonal antibodies; s/e- severe allergic inflam infusion
rxn- premedicate b4.
ANTI TNF Monoclonal antibody prevents TNF molecules from binding to TNF cell
surface/impacts inflammatory response; tx RA/chron's/ulcer colitis/plaque psioriasis/psoriatic
arthritis. - Answer Adalimumab (Humira); SC EVERY OTHER WEEK