BCH 4053 FINAL EXAM QUIZLET COMBINED
QUESTIONS WITH CORRECT ANSWERS
1. At which pH value would histidine (pKa of 1.8, 6.0, and d. 11.0
|| || || || || || || || || || | | ||
9.2) be found with a net negative charge?
|| || || || || || ||
a. 1.0
b. 8.0
c. 12.0
d. 11.0
e. none of the above || || ||
2. All are structural and functional advantages to qua-
|| || || || || || ||
C. Cholesterol:
ternary structure EXCEPT:
|| || ||
the primary
|| ||
A. Cooperativity component of
|| ||
B. Stability "saturated" fa
|| | |
C. Brining catalytic sites together || || ||
D. Genetic economy and efficiency || || ||
E. All are true || ||
3. Which of the following lipids is correctly defined?
|| || || || || || ||
A. Triacylglycerol: formed from glycerol and 3 fatty || || || || || ||
acids, primary lipid of membranes
|| || || || ||
B. Phospholipid: contains glycerol with 2 fatty acids || || || || || ||
and a phosphate, very often forms bilayers
|| || || || || || ||
1 ||/ ||
109
,E. All are true
|| || ||
B. Phospholipid: contains glycerol with 2 fatty acids and a phosphate, very
|| || || || || || || || || || ||
often forms bilayers
|| || ||
2 ||/ ||
109
, D. Palmitic acid: the most commonly produced unsat-
|| || || || || ||
urated fatty acid in animals
| | || || || ||
4. The amino acid residue most likely to be found in a
|| || || || || || || || || || A. Glycine||
beta turn is:
|| || ||
A. glycine
B. alanine
C. valine
D. glutamic acid | |
E. leucine
5. Why should the core of most globularand membrane B. Highly polar N-H and
| | | | | | | | || || || || ||
proteins consist almost entirely of alpha helices
| | C=O moieties of the pep- | | || | | || | | || || || ||
and beta sheets?
| | || || tide backbone must be || || || ||
neutralized in the hy- || || || ||
A. Hydrogen bonded structures must be kept drophobic core of the
| | | | || | | | |
|| || || ||
away from the water solvent
| | ||
pro- tein
|| || ||
|| ||
B. Highly polar N-H and C=O moieties of the
| | | | | | || | | | | | |
peptide backbone must be neutralized in the
| | || || || || || ||
hydrophobic core of the protein
|| || || || ||
C. Hydrogen bonding only occurs in the core of pro- | | | | | | | |
teins
||
D. Trapped water stabilizes the helix and sheet struc- || || || || || || ||
tures
| |
E. None are true || ||
6. Bacteria in a colder environment would have
| | | | | | | | | | | | A. More unsaturated ||
mem- branes with
| | || || fatty acids
|| ||
3 ||/ ||
109
, A. More unsaturated fatty acids | | |
B. More saturated fatty acids | | |
C. Higher rates of metabolism | | | | | |
D. Higher sphingolipid content | | | |
E. Higher cholesterol content | | | |
7. To make a buffer at pH 7.4, which two compounds
|| || || || || || || || || E. Disodium hydrogen
|| ||
would you choose? (pKa for phosphoric acid are 2.1,
|| || || || || || || || || phosphate and sodium hy-
|| || || ||
6.9, 12.4)
| | || drogen phosphate
|| ||
A. Phosphoric acid and disodium hydrogen phos- || || || || ||
phate
||
B. HCl and disodium hydrogen phosphate
|| || || ||
C. Disodium hydrogen phosphate and NaOH || || || ||
D. Disodium hydrogen phosphate and trisodium | | | |
phosphate
||
E. Disodium hydrogen phosphate and sodium | | | | | | | |
hydro- gen phosphate
| | || ||
8. The Gº for ATP hydrolysis and PEP hydrolysis are -30.5 B. -31.4 kJ/mole
|| || || || || || || || || || || ||
kJ/mole and -61.9 kJ/mole, respectively. Find G of:
|| || || || || || ||
PEP + ADP ATP + pyruvate
|| || || || || ||
A. -92.4 kJ/mole ||
B. -31.4 kJ/mole ||
C. -2.4 kJ/mole ||
D. +2.4 kJ/mole
|| ||
E. Cannot answer the question
|| || || ||
9. All of the following are true except:
|| || || || || || A. Asp and Asn are acidic
|| || || || ||
amino acids
|| ||
A. Asp and Asn are acidic amino acids
|| || || || || ||
4 ||/ ||
109
QUESTIONS WITH CORRECT ANSWERS
1. At which pH value would histidine (pKa of 1.8, 6.0, and d. 11.0
|| || || || || || || || || || | | ||
9.2) be found with a net negative charge?
|| || || || || || ||
a. 1.0
b. 8.0
c. 12.0
d. 11.0
e. none of the above || || ||
2. All are structural and functional advantages to qua-
|| || || || || || ||
C. Cholesterol:
ternary structure EXCEPT:
|| || ||
the primary
|| ||
A. Cooperativity component of
|| ||
B. Stability "saturated" fa
|| | |
C. Brining catalytic sites together || || ||
D. Genetic economy and efficiency || || ||
E. All are true || ||
3. Which of the following lipids is correctly defined?
|| || || || || || ||
A. Triacylglycerol: formed from glycerol and 3 fatty || || || || || ||
acids, primary lipid of membranes
|| || || || ||
B. Phospholipid: contains glycerol with 2 fatty acids || || || || || ||
and a phosphate, very often forms bilayers
|| || || || || || ||
1 ||/ ||
109
,E. All are true
|| || ||
B. Phospholipid: contains glycerol with 2 fatty acids and a phosphate, very
|| || || || || || || || || || ||
often forms bilayers
|| || ||
2 ||/ ||
109
, D. Palmitic acid: the most commonly produced unsat-
|| || || || || ||
urated fatty acid in animals
| | || || || ||
4. The amino acid residue most likely to be found in a
|| || || || || || || || || || A. Glycine||
beta turn is:
|| || ||
A. glycine
B. alanine
C. valine
D. glutamic acid | |
E. leucine
5. Why should the core of most globularand membrane B. Highly polar N-H and
| | | | | | | | || || || || ||
proteins consist almost entirely of alpha helices
| | C=O moieties of the pep- | | || | | || | | || || || ||
and beta sheets?
| | || || tide backbone must be || || || ||
neutralized in the hy- || || || ||
A. Hydrogen bonded structures must be kept drophobic core of the
| | | | || | | | |
|| || || ||
away from the water solvent
| | ||
pro- tein
|| || ||
|| ||
B. Highly polar N-H and C=O moieties of the
| | | | | | || | | | | | |
peptide backbone must be neutralized in the
| | || || || || || ||
hydrophobic core of the protein
|| || || || ||
C. Hydrogen bonding only occurs in the core of pro- | | | | | | | |
teins
||
D. Trapped water stabilizes the helix and sheet struc- || || || || || || ||
tures
| |
E. None are true || ||
6. Bacteria in a colder environment would have
| | | | | | | | | | | | A. More unsaturated ||
mem- branes with
| | || || fatty acids
|| ||
3 ||/ ||
109
, A. More unsaturated fatty acids | | |
B. More saturated fatty acids | | |
C. Higher rates of metabolism | | | | | |
D. Higher sphingolipid content | | | |
E. Higher cholesterol content | | | |
7. To make a buffer at pH 7.4, which two compounds
|| || || || || || || || || E. Disodium hydrogen
|| ||
would you choose? (pKa for phosphoric acid are 2.1,
|| || || || || || || || || phosphate and sodium hy-
|| || || ||
6.9, 12.4)
| | || drogen phosphate
|| ||
A. Phosphoric acid and disodium hydrogen phos- || || || || ||
phate
||
B. HCl and disodium hydrogen phosphate
|| || || ||
C. Disodium hydrogen phosphate and NaOH || || || ||
D. Disodium hydrogen phosphate and trisodium | | | |
phosphate
||
E. Disodium hydrogen phosphate and sodium | | | | | | | |
hydro- gen phosphate
| | || ||
8. The Gº for ATP hydrolysis and PEP hydrolysis are -30.5 B. -31.4 kJ/mole
|| || || || || || || || || || || ||
kJ/mole and -61.9 kJ/mole, respectively. Find G of:
|| || || || || || ||
PEP + ADP ATP + pyruvate
|| || || || || ||
A. -92.4 kJ/mole ||
B. -31.4 kJ/mole ||
C. -2.4 kJ/mole ||
D. +2.4 kJ/mole
|| ||
E. Cannot answer the question
|| || || ||
9. All of the following are true except:
|| || || || || || A. Asp and Asn are acidic
|| || || || ||
amino acids
|| ||
A. Asp and Asn are acidic amino acids
|| || || || || ||
4 ||/ ||
109
