NR507 MIDTERM EXAM 2 (NEW 2024/ 2025
UPDATE) ADVANCED PATHOPHYSIOLOGY |
QUESTIONS AND VERIFIED ANSWERS
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Terms in this set (183)
Innate immunity the immunity we are born with
1st line: physical, mechanical, & biochemical barriers
Immune response: 3
2nd line: the inflammatory response
levels/lines of protection
3rd line: lymphocyte production
most important immune intact skin and mucous membranes (impermeable
defense barrier)
pathogen associated molecular pattern
surfaces of bacteria, viruses, and other microbes are
PAMP
covered with many foreign proteins
foreign
damage associated molecular pattern
many proteins are released from inside our cells when
DAMP
they are damaged
foreign
, pattern recognition receptors
surfaces of WBCs contain these receptor sites
PRR
-continuously interact with any material they
encounter to ID it as "self" or "non-self" (foreign; PAMP
or DAMP)
Cell movement that occurs in response to chemical
Chemotaxis
stimulus
"cell eating"
1. opsonization and adherence
2. engulfment - WBC surrounds and ingests Ag
3. Fusion of phagosome with lysosome
Phagocytosis
4. destruction - phagosome digested by lysozyme,
H202, acids, and other toxic chemicals inside the
lysosomes
5. egestion
Hypersensitivity Type 1:_____ Allergic reaction
Hypersensitivity: Type 1 IgE
Mediated by ______
Hypersensitivity: Type 1 mast cell degranulation
Inflammation due to
_____________
Hypersensitivity: Type 1 itching, rash
local symptoms
Hypersensitivity: Type 1 wheezing
systemic symptoms
Hypersensitivity: Type 1 anaphylactic reaction-systemic response-
most dangerous form hypotension, severe bronchoconstriction
Hypersensitivity: Type 1 epinephrine
main treatment ___________
Hypersensitivity Type 2: Cytotoxic reaction; tissue specific (example: thyroid
_________________ tissue) hapten causes mediation of IgE or IgM
UPDATE) ADVANCED PATHOPHYSIOLOGY |
QUESTIONS AND VERIFIED ANSWERS
Save
Terms in this set (183)
Innate immunity the immunity we are born with
1st line: physical, mechanical, & biochemical barriers
Immune response: 3
2nd line: the inflammatory response
levels/lines of protection
3rd line: lymphocyte production
most important immune intact skin and mucous membranes (impermeable
defense barrier)
pathogen associated molecular pattern
surfaces of bacteria, viruses, and other microbes are
PAMP
covered with many foreign proteins
foreign
damage associated molecular pattern
many proteins are released from inside our cells when
DAMP
they are damaged
foreign
, pattern recognition receptors
surfaces of WBCs contain these receptor sites
PRR
-continuously interact with any material they
encounter to ID it as "self" or "non-self" (foreign; PAMP
or DAMP)
Cell movement that occurs in response to chemical
Chemotaxis
stimulus
"cell eating"
1. opsonization and adherence
2. engulfment - WBC surrounds and ingests Ag
3. Fusion of phagosome with lysosome
Phagocytosis
4. destruction - phagosome digested by lysozyme,
H202, acids, and other toxic chemicals inside the
lysosomes
5. egestion
Hypersensitivity Type 1:_____ Allergic reaction
Hypersensitivity: Type 1 IgE
Mediated by ______
Hypersensitivity: Type 1 mast cell degranulation
Inflammation due to
_____________
Hypersensitivity: Type 1 itching, rash
local symptoms
Hypersensitivity: Type 1 wheezing
systemic symptoms
Hypersensitivity: Type 1 anaphylactic reaction-systemic response-
most dangerous form hypotension, severe bronchoconstriction
Hypersensitivity: Type 1 epinephrine
main treatment ___________
Hypersensitivity Type 2: Cytotoxic reaction; tissue specific (example: thyroid
_________________ tissue) hapten causes mediation of IgE or IgM
