ADVANCED PATHOPHYSIOLOGY NR507 ADVANCED PATHOPHYSIOLOGY MIDTERM

ADVANCED PATHOPHYSIOLOGY NR507 ADVANCED PATHOPHYSIOLOGY MIDTERM Hypersensitivity: Type 1 - correct answers-Type 1: Allergic reaction, Mediated by IgE, Inflammation due to mast cell degranulation Inflammation due to mast cell degranulation Local symptoms: -itching -rash Systemic symptoms: -wheezing Most dangerous = anaphylactic reaction systemic response of hypotension, severe bronchoconstriction Main treatment: epinephrine reverses the effects Hypersensitivity: Type 2 - correct answers-Type 2: Cytotoxic reaction; tissue specific (ex: thyroid tissue) Macrophages are the primary effectors cells involved Can cause tissue damage or alter function Grave's disease (hyperthyroidism) - example of altering thyroid function, but does not destroy thyroid tissue