!! !! !! !! !! !! !
EDITION BY GARDENHIRE/ALL CHAPTERS S 1-23
!! !! !! !! !! !!
,CH 01: Introduction to Respiratory Care Pharmacology
!! !! !! !! !! !! !!
Gardenhire: Rau’s Respiratory Care Pharmacology, 11th
!! !! !! !! !! !!
Edition
!!
MULTIPLE !!RESPONSE
1. The !!listing !!of !!a !!drug !!and !!the !!amount !!of !!drug !!are !!found !!in !!which !!part !!of !!a !!prescription?
a. Superscription
b. Inscription
c. Subscription
d. Transcription !!(signature)
PRECISE !!ANSWER:-B
Reasoning !!:->>>The !!superscription !!directs !!the !!registered !!pharmacist !!to !!take !!the !!drug !!listed
!!and !!prepare!the !!drug; !!the !!inscription !!lists !!the !!name !!and !!quantity !!of !!the !!drug !!being !!prescribed;
!!the !!subscription!provides !!directions !!to !!the !!registered !!pharmacist !! for !!preparing !!the !!drug; !!and
!!the !!transcription, !!or !!signature, !!is !!the !! information !!the !! registered !!pharmacist !! writes !!on !!the !! label
!!as !! instructions !!to !!the !! patient.
REFERENCE: ! ! p. !!7
2. If !!generic !!substitution !!is !!permitted !!on !!a !!prescription:
a. drug !!from !!only !!one !!manufacturer !!must !!be !!given.
b. drug !!formulation !!may !!be !!changed !!by !!the !!registered !!pharmacist.
c. any !!manufactured !!brand !!of !!the !!drug !!listed !!may !!be !!given.
d. drug !!strength !!may !!be !!changed !!by !!the !!registered !!pharmacist.
PRECISE !!ANSWER:-C
Reasoning !!:->>>A !!generic !!substitution !!allows !!any !!brand !!of !!a !!drug !!to !!be !!given, !!but !!the
!!registered !!pharmacist !!may !!not !!change !!a !!drug !!formulation !!without !!specific !!permission !!from
!!the !!prescribing !!physician. !!A !!physician !!can !!indicate !!to !!the !!registered !!pharmacist !!that !!generic
!!substitution !!is !!permitted !!in !!the !!filling !!of !!the !!prescription. !!In !!such !!a !!case, !!the !!registered
!!pharmacist !!may !!provide !!any !!manufacturer’s !!version !!of !!the !!prescribed !!drug, !!rather !!than !!a
!!specific !!brand. !!However, !!the !!registered !!pharmacist !!may !!not !!change !!the!s trength !!of !!a !!drug
!!without !! specific !!permission !!from !!the !!prescribing !!physician.
REFERENCE: ! ! p. !!8
3. The !!study !!of !!drug, !!including !!their !!origin, !!properties, !!and !!interactions !!with !!living !!organisms, ! !is
known !!as
!!
a. pharmacogenetics.
b. pharmacology.
c. therapeutics.
d. toxicology.
PRECISE !!ANSWER:-B
Reasoning:->>>Pharmacogenetics !!is !!the !!study !!of !!the !!interrelationship !!of !!genetic !!differences !!and
!!drug !!effects. !!Pharmacology !!is !!the !!study !!of !!drug !!(chemicals), !!including !!their !!origin, !!properties,
!!and !!interactions!with !!living !! organisms.
Therapeutics !!is !!the !!art !!of !!treating !!illness !!with !!drug. !!Toxicology !!is !!the !!study !!of !!toxic !!substances
!!and !!their!pharmacologic !!actions, ! ! including !! antidotes !!and !!poison !!control.
REFERENCE: ! ! p. !!3
,4. The !!brand !!name !!given !!to !!a !!drug !!by !!a !!particular !!manufacturer !!is !!known !!as !!the !!drug’s
a. chemical !!name.
b. generic !!name. !!c.official !!name. !!d.trade !!name.
PRECISE !!ANSWER:-D
Reasoning:->>>The !!chemical !!name !!indicates !!the !!drug’s !!chemical !!structure. !!The !!generic !!name !!is
!!assigned!by !!the !!United !! States
, Adopted !!Name !!Council !!and !!is !!usually !!based !!loosely !!on !!the !!drug’s !!chemical !!structure. !!The !!official
!!name !! is!the
name !!given !!to !!the !!generic !!name !!once !!a !!drug !!becomes !!fully !!approved !!for !!general !!use !!and !!is
!!admitted !!to !!the !!United !!States !!Pharmacopeia–National !!Formulary. !!The !!trade !!name !!is !!the
!!brand, !!or !!proprietary, !!name !!given !!by !!a !!particular !! manufacturer. !!For !!example, !!the !!generic !! drug
!!albuterol !!is !!currently !!marketed !!by !!Schering-!Plough !!as !!Proventil
® !!and !!by !!GlaxoSmithKline !!as
!!Ventolin .
®
REFERENCE: ! ! p. !!5
5. To !!find !!official !!information !!about !!drug !!(according !!to !!the !!FDA), !!you !!need !!to !!go !!to !!the
a. Physician’s !!Desk !!Referenceerence !!(PDR).
b. Basic !!& !!Clinical !!Pharmacology.
c. United !!States !!Pharmacopeia–National !!Formulary !!(USP-NF).
d. Goodman !!& !!Gilman’s !!The !!Pharmacological !!Basis !!of !!Therapeutics.
PRECISE !!ANSWER:-C
Reasoning:->>>Because !!the !!PDR !!is !!prepared !!by !!drug !!manufacturers !!themselves, !!it !!may !!be
!!lacking !!in !!objectivity. !!Basic !!& !!Clinical !!Pharmacology !!covers !!only !!general !!pharmacologic
!!principles !!and !!drug !!classes. !!Goodman !!& !!Gilman’s !!The !!Pharmacological !!Basis !!of !!Therapeutics
!!covers !!only !!general !!pharmacologic!principles !!and !!drug !!classes. !!The !!USP-NF !!is !!a !!book !!of
!!standards !!containing !!information !!about !!drugs, !!dietary !!supplements, !!and !!medical !!devices. !!The
!!U.S. !!Food !!and !!Drug !!Administration !!(FDA)!considers !!this !!book !!the !!official !!standard !!for ! ! drug
!!marketed !!in !!the !!United !! States.
REFERENCE: ! ! p. !!5
6. Drug !!may !!be !!obtained !!from !!which !!of !!the !!following !!sources?
a. Plants
b. Animals
c. Minerals
d. Plants, !!animals, !!and !!minerals
PRECISE !!ANSWER:-D
Reasoning:->>>Drug !!may !!be !!obtained !!from !!plants !!(e.g., !!digitalis), !!animals !!(e.g., !!insulin), !!and
!!minerals!(e.g., !!magnesium !!sulfate).
REFERENCE: ! ! p. !!5
7. The !!branch !!of !!the !!U.S. !!government !!responsible !!for !!the !!process !!of !!approving !!drug !!for !!clinical !!use
is !!the
!!
a. USAN !!Council.
b. FDA.
c. USP-NF.
d. PDR.
PRECISE !!ANSWER:-B
Reasoning:->>>The !!United !!States !!Adopted !!Name !!(USAN) !!Council !!is !!responsible !!for !!assigning
!!a !!generic !!name !!to !!a !!chemical !!that !!appears !! to !!have !!therapeutic !!use. !!The !!U.S. !!Food !!and !!Drug
!!Administration !!(FDA) !!is !!responsible !!for !!the !!process !!of !!approving !!drug !!for !!clinical !!use. !!The
!!process !!by !!which !!a !!chemical !!moves!from !!the !!status !!of !!a !!promising !!potential !!drug !!to !!one !!fully
!!approved !!by !!the !!FDA !!for !!general !!clinical !!use !! is,!on !!average, !!long, !!costly, !!and !!complex. !!Cost