THIS WEEK FOCUSES
NR546: Advanced NEUROTRANSMITTER
DRUG METABOLISM
Psychopharmacology:
CYTOCHROME P450
AND THE AGONIST
SPECTRUM!
Week 2
By: Avery Selch BSN, CCRN
, Cytochrome P450
Phase 1 metabolism: How does this work?
What are examples of CYP450 inhibitors?
VISACKGQ
What are examples of CYP450 inducers?
CRAP GPS
Are inducers or inhibitors responsible for decreasing medication
metabolism?
If you give a patient an inducer, what might you have to do to the
dose?
If a patient is an alcoholic, should you increase or decrease their dose
of aripiprazole?
If a patient is a smoker, what does the PMHNP need to keep in mind?
NR546: Advanced NEUROTRANSMITTER
DRUG METABOLISM
Psychopharmacology:
CYTOCHROME P450
AND THE AGONIST
SPECTRUM!
Week 2
By: Avery Selch BSN, CCRN
, Cytochrome P450
Phase 1 metabolism: How does this work?
What are examples of CYP450 inhibitors?
VISACKGQ
What are examples of CYP450 inducers?
CRAP GPS
Are inducers or inhibitors responsible for decreasing medication
metabolism?
If you give a patient an inducer, what might you have to do to the
dose?
If a patient is an alcoholic, should you increase or decrease their dose
of aripiprazole?
If a patient is a smoker, what does the PMHNP need to keep in mind?
