what is neurulation affected by during development? - Answersa lack of folic acid (vit B9)
when and where does the notochord form? - Answersday 18, in the mesoderm
what does the mesoderm produce to cause neurulation? - Answerssonic hedgehog
What does sonic hedgehog do to the ectoderm? - Answerscauses it to thicken to form the neural plate
list the order of development of the neural tube - Answersplate, folds, groove, neural crest, tube
name 3 types of neural tube defects - Answersspina bifida occulta, meningocele, meningomyelocele
what is spina bifida occulta? - Answersfailure of the vertebral arch to close, but the spinal cord remains
within the vertebral space with no serious effects
what is a meningocele? - Answersprotrusion of the meninges and CSF outside of the normal space, but
the cord is still within the vertebra (palpable under skin, because arch is open)
what is a meningomyelocele? - Answersprotrusion of the meninges AND spinal cord outside of the
normal space (palpable under skin), requires surgery to avoid damaging cord
what part of the neural tube becomes white matter later? - Answersmarginal layer (an "i" in white and
marginal)
what part of the neural tube becomes grey matter later? - Answersmantle layer (an "e" in grey and
mantle)
what do the sensory neurons from the neural crest become? - Answersdorsal root ganglion
what do the cells in the alar plate of the mantle layer become? - Answersinterneurons
what do the cells in the basal plate of the mantle layer become? - Answersmotor neurons (lots of motor
work to be able to use "basal" in your food)
what does the central cavity of the neural tube become? - Answersthe central canal of the spinal cord
what arises from the neural crest cells? - Answersperipheral nerves
what is the mnemonic for the neural crest cell derivatives? - AnswersDAMES
what does the "D" in DAMES stand for? - AnswersDorsal root ganglion
what does the "A" in DAMES stand for? - AnswersAdrenal medulla
what does the "M" in DAMES stand for? - AnswersMelanocytes, Meninges (pia and arachnoid), and
Macroglia
, what does the "E" in DAMES stand for? - AnswersEnteric ganglia
what does the "S" in DAMES stand for? - AnswersSympathetic ganglia, Schwann cells
where does the dura mater originate? - Answersmesoderm
how long is the average spinal cord? - Answers18 inches
where does the spinal cord begin and end? - Answersforamen magnum to L1/L2 in adults
what is the end of the spinal cord called? - Answersconus medullaris
what continues past the conus medullaris in the dural sac? - Answerscauda equina
what is the filum terminale? - Answersextension of the pia mater
where does the filum terminale attach? - Answersinternally, the end of the dural sac; externally, the
coccyx
where does the dural sac end? - AnswersS2 (dura covers the rest of the nerves of the cauda equina)
what is the average diameter of the spinal cord? - Answers1-2 cm
why are there enlargements in the cervical and lumbar regions of the spinal cord? - Answersto
accommodate for plexuses innervating the limbs
name the meninges from outermost to the innermost layer - Answersdura (tough), arachnoid
(spiderweb), pia (thin, on spinal cord)
what is continuous with the epineurium around the spinal nerves? - Answersdura mater
what is normally found in the epidural (extradural) space? - Answersfat and vessels
what is normally found in the subdural space? - Answersnothing should be here (between arachnoid and
dura)
what is normally found in the subarachnoid space? - AnswersCSF (cerebrospinal fluid)
what are two specializations of the pia mater? - Answersdentate ligament and filum terminale
where are dentate ligaments found? - Answersanchoring the spinal cord to the dura, extending from
craniovertebral junction to T12
how many "teeth" are found per dentate ligament? - Answers21
what are cell bodies outside of the spinal cord called? - Answersganglia
what does VEMDAS mean? - Answersventral, efferent, motor; dorsal, afferent, sensory (thanks, Brad)