QUESTIONS AND 100% VERIFIED ANSWERS /GRA DED A+
/GUARANTEED PASS!!
Dosing for high dose colchicine
- answer-1.2 mg followed by 0.6 mg every 4 to 6 hours; or 4.8 mg total.
Dosing for low dose colchicine
- answer-1.2 mg followed by 0.6 one hour later or 1.8 mg total
1st line for mild or moderate pain, inflammation
- answer-NSAIDS
A patient develops toxic goiter. What's the recommended treatment?
- answer-Methimazole
inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone
synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous acid (HOI),
enzyme linked hypoiodate (EOI) facilitating iodine's addition to tyrosine residues
on the hormone precursor thyroglobulin, a necessary step in the synthesis of
triiodothyronine (T3) and thyroxine (T4).
It is used to treat hyperthyroidism in patients with toxic adenoma or toxic goiter in
preparation for more definitive therapy with radioiodine or surgery. So short
answer, Methimazole.
A recent Cochrane review found that in small studies use of diuretics appear to
have
- answer-improved mortality in individuals with heart failure however the extent to
which these results can be extrapolated to a general population is unclear due to the
small number of participants in cited studies.
A woman who is pregnant and has hyperthyroidism is best managed by a specialty
team who will most likely treat her with:
a. Methimazole
b. Propylthiouracil (PTU)
c. Radioactive iodine
d. Nothing, treatment is best delayed until after her pregnancy ends
- answer-B. Propylthiouracil (PTU)
,ACEs: Why cough as common side effect that causes need for med stoppage?
- answer-Due to the buildup of bradykinin in the lungs - Shadow health module has
great visual of this
Acteaminophen being cox 2 does not inhibit
- answer-production of pro clotting thromboxjnes.
Acute overdose of acetaminophen can cause what?
- answer-Potentially fatal liver damage.
Administration of exenatide is by subcutaneous injection:
a. 30 minutes prior to morning meal
b. 15 minutes after the evening meal
c. 60 minutes prior to the morning and evening meal
d. 60 minutes before each meal daily
- answer-C. 60 minutes prior to the morning and evening meal
ADV effects of corticosteroids if given longer than 6 months?
- answer-The main thing you want to worry about is osteoporosis, it can also
worsen diabetic control and patients should report any tarry black stools or
abdominal pain. PEPTIC ULCER DISEASE.
ADV effects of procainamide
- answer-occur even more if the daily doses are increased
ADV of corticos after 6 months
- answer-osteoporosis, can also worsen diabetic control (raise BGL)
Adverse side effects of amlodipine include: common and dose-related
- answer-peripheral edema, dizziness and palpitations, and flushing;
Adverse side effects of amlodipine include: common and not dose-related
- answer-include fatigue, nausea, abdominal pain, and somnolence;
Adverse side effects of amlodipine rare
- answer-blood disorders, impotence, depression, insomnia, tachycardia, gingival
enlargement, hepatitis, and jaundice.
All diabetic patients with known cardiovascular disease should be treated with:
a. Beta blockers to prevent MIs
,b. Angiotensin-converting enzyme inhibitors and aspirin to reduce risk of
cardiovascular events
c. Sulfonylureas to decrease cardiovascular mortality
d. Pioglitazone to decrease atherosclerotic plaque buildup
- answer-Angiotensin-converting enzyme inhibitors and aspirin to reduce risk of
cardiovascular events.
Allopurinol is used for what?
- answer-Gout
Alpha glucosidase inhibitors...acarbose** MOA
- answer-work by preventing the digestion of carbohydrates.
Amiodarone (Class III anti-arrhythmias)-MOA
- answer-blocks Na & Ca channels. Considered 2nd or 3rd line
Amiodarone adverse effect/ pt education
- answer-ulmonary fibrosis (xray needed every 6 months), hypo/hyperthyroidism
(monitor thyroid levels), bluish skin color, eye problems (optic neuropathy)
• Do NOT give during pregnancy
• Do Not take w/ grapefruit juice
Amlodipine is a medication used to treat
- answer-high blood pressure and prevent chest pain; it can also be used for heart
failure.
Amlodipine MOA
- answer-It is a long-acting dihydropyridine calcium channel blocker. By widening
blood vessels, it lowers blood pressure. In angina, it increases blood flow to the
heart muscle to relieve pain due to angina.
An ACE inhibitor and what other class of drug may reduce proteinuria in patients
with diabetes better than either drug alone?
a. Beta blockers
b. Diuretics
c. Non-dihydropyridine calcium channel blockers
d. Angiotensin II receptor blockers
- answer-C. Non-dihydropyridine calcium channel blockers
Angiotensin-converting enzyme (ACE) inhibitors treat hypertension because they:
, a. Reduce sodium and water retention
b. Decrease vasoconstriction
c. Increase vasodilation
d. All of the above
- answer-All of the above. The renin-angiotensin system is systemically and locally
driven. The systemic process is triggered by the kidneys' response to decreased
effective blood volume and begins with the secretion of insulin from the renal
cortex. Once released, renin cleaves angiotensinogen to form angiotensin-I. This
product in turn is catalyzed by angiotensin converting enzyme or ACE, formed
primarily in the pulmonary vasculature and angiotensin-II. This potent
vasoconstrictor effects tissues and systems throughout the body, research shows
that these vasoconstrictor effects are attenuated by ACE inhibition. Be sure to
understand the RAAS system!
Annamarie has type 2 diabetes and a high triglyceride level. She has gemfibrozil
prescribed to treat her hypertriglyceridemia. A history of which of the following
might contraindicate the use of this drug?
a. Reactive airway disease/asthma
b. Inflammatory bowel disease
c. Allergy to aspirin
d. Gallbladder disease
- answer-Gallbladder disease
Antipyretic effects
- answer-may be due to action on the hypothalamus resulting in an increase of
peripheral blood flow, basil dilation, and subsequent heat dissipation.
ARBS facts
- answer-no cough, K+ sparing
avoid what with warfarin
- answer-Vit K rich foods and Pregnancy
BB Inotropic? Chronotropic? Dromotropic?
- answer-o Inotropic contractility
o Chronotropic speed of conduction
o Dromotropic speed for impulse from SA to AV nodes
BBs
- answer-lol