LATEST UPDATE WGU D027 ADVANCED
PATHOPHARMACOLOGICAL
FOUNDATIONS (ACTUAL 2025-2026)
QUESTIONS AND ANSWERS
Why are aminosalicylates used for in patients with Crohn's
A A A A A A A A A
disease? - ---answers A- Reduce inflammation
A A A
What are some aminosalicylates that are used to treat Crohn's
A A A A A A A A A A
disease? - ---answers - Sulfasalazine
A A A
- Mesalamine
Why are corticosteroids used for in patients with Crohn's
A A A A A A A A A
disease? - ---answers A - Reduce inflammation
A A A
- Only used if aminosalicylates are not effective during an
A A A A A A A A A
exacerbation
What are the sickle cell and parent traits? - ---answers
A A A A A A A A A -
Children who have, 25%
A A A A
- Children who do not have and are not carriers, 25%
A A A A A A A A A
- Children who are carriers, 50% A A A A
What is Huntington's disease? - ---answers
A A A A A -
Autosomal dominant disorder
A A A
- A person only needs one copy of each of the affected gene to d
A A A A A A A A A A A A A
evelop the disorder
A A
- Each child has a 50% chance of inheriting the gene that
A A A A A A A A A A A
causes the disease
A A
,LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Leads to progressive degeneration of nerve cells that affects
A A A A A A A A A
movement, cognitive functions, and emotions A A A A
What is an example of an autosommal dominant disorder? - --
A A A A A A A A A A
-answers - Huntington's disease A A
What is an example of an autosomal recessive disorder? - ---
A A A A A A A A A A
answers
A - Cystic fibrosis A A
What is cystic fibrosis? - ---answers
A A A A A -
Autosomal recessive disorder
A A A
- The lungs and the digestive system get clogged with mucus
A A A A A A A A A
- Affects the pancreas causing secretions in the lungs
A A A A A A A
- Caused by CTFR mutation A A A
What are some ways that cystic fibrosis affects the different
A A A A A A A A A A
parts in the body? - ---answers
A A - A A A
ALungs: block airways causing inflammation and increasing
A A A A A A A
the risk of infection, pulmonary hypertension, and tissue da
A A A A A A A A
mage
- Digestive tract: block secretion of digestive enzymes from th
A A A A A A A A
e pancreases leading to malabsorption and malnutrition, can al
A A A A A A A A
so lead to chronic pancreatitis
A A A A
,LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Liver: blockage of the bile ducts can interfere with the liver's
A A A A A A A A A A A
ability to clear toxins from the blood leading to scarring, gallst
A A A A A A A A A A
ones, and cirrhosis
A A
- Reproductive system: structural problems that renders the A A A A A A A
majority of men with this disorder to be infectable
A A A A A A A A
- Endocrine system: blockage of insulin- A A A A
producing cells on the pancreas (islets of Langerhans) can l
A A A A A A A A A
ead to type of diabetes that has characteristics of both type 1
A A A A A A A A A A A
Aand type 2 diabetes
A A A
What are some symptoms of patients with cystic fibrosis? - ---
A A A A A A A A A A
answers
A - Very salty-tasting skin A A A
- Postnasal drip, sinusitis A A
- Shortness of breath A A
- Repeated lung infections A A
- Foul-smelling, bulky greasy stools A A A
- Poor growth A
- Male infertility A
What are some diagnostic tests used to diagnose cystic fibros
A A A A A A A A A
is? - ---answers
A A -
ASweat test (measures the amount of chloride in sweat)
A A A A A A A A
, LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Genetic test (detects chromosomal mutations associated with
A A A A A A A
the disease)
A
What is an example of x-linked dominant disorder? - ---
A A A A A A A A A
answers
A -
Duchenne muscular dystrophy inheritance (DMD)
A A A A A
- Color blindness A
What is Duchenne Muscular Dystrophy? ----- answers
A A A A - X-A
linked dominant disorderA A
- Until recently, children with this order did not live beyond t
A A A A A A A A A A
heir teens A
- Life expectancy now 30's and some into their 40's to 50's
A A A A A A A A A A
- Affects the muscles, leading to muscle wasting that worsens
A A A A A A A A A
over time A
- Almost always affects boys and symptoms being early in
A A A A A A A A A
childhood
What are some signs and symptoms in patients with Duchenn
A A A A A A A A A
e Muscular Dystrophy? - ---answers ------------------ Difficulty
A A A A
standing up, walking, and climbing stairs
A A A A A
- May have heart and lung problems
A A A A A
- Scoliosis
PATHOPHARMACOLOGICAL
FOUNDATIONS (ACTUAL 2025-2026)
QUESTIONS AND ANSWERS
Why are aminosalicylates used for in patients with Crohn's
A A A A A A A A A
disease? - ---answers A- Reduce inflammation
A A A
What are some aminosalicylates that are used to treat Crohn's
A A A A A A A A A A
disease? - ---answers - Sulfasalazine
A A A
- Mesalamine
Why are corticosteroids used for in patients with Crohn's
A A A A A A A A A
disease? - ---answers A - Reduce inflammation
A A A
- Only used if aminosalicylates are not effective during an
A A A A A A A A A
exacerbation
What are the sickle cell and parent traits? - ---answers
A A A A A A A A A -
Children who have, 25%
A A A A
- Children who do not have and are not carriers, 25%
A A A A A A A A A
- Children who are carriers, 50% A A A A
What is Huntington's disease? - ---answers
A A A A A -
Autosomal dominant disorder
A A A
- A person only needs one copy of each of the affected gene to d
A A A A A A A A A A A A A
evelop the disorder
A A
- Each child has a 50% chance of inheriting the gene that
A A A A A A A A A A A
causes the disease
A A
,LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Leads to progressive degeneration of nerve cells that affects
A A A A A A A A A
movement, cognitive functions, and emotions A A A A
What is an example of an autosommal dominant disorder? - --
A A A A A A A A A A
-answers - Huntington's disease A A
What is an example of an autosomal recessive disorder? - ---
A A A A A A A A A A
answers
A - Cystic fibrosis A A
What is cystic fibrosis? - ---answers
A A A A A -
Autosomal recessive disorder
A A A
- The lungs and the digestive system get clogged with mucus
A A A A A A A A A
- Affects the pancreas causing secretions in the lungs
A A A A A A A
- Caused by CTFR mutation A A A
What are some ways that cystic fibrosis affects the different
A A A A A A A A A A
parts in the body? - ---answers
A A - A A A
ALungs: block airways causing inflammation and increasing
A A A A A A A
the risk of infection, pulmonary hypertension, and tissue da
A A A A A A A A
mage
- Digestive tract: block secretion of digestive enzymes from th
A A A A A A A A
e pancreases leading to malabsorption and malnutrition, can al
A A A A A A A A
so lead to chronic pancreatitis
A A A A
,LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Liver: blockage of the bile ducts can interfere with the liver's
A A A A A A A A A A A
ability to clear toxins from the blood leading to scarring, gallst
A A A A A A A A A A
ones, and cirrhosis
A A
- Reproductive system: structural problems that renders the A A A A A A A
majority of men with this disorder to be infectable
A A A A A A A A
- Endocrine system: blockage of insulin- A A A A
producing cells on the pancreas (islets of Langerhans) can l
A A A A A A A A A
ead to type of diabetes that has characteristics of both type 1
A A A A A A A A A A A
Aand type 2 diabetes
A A A
What are some symptoms of patients with cystic fibrosis? - ---
A A A A A A A A A A
answers
A - Very salty-tasting skin A A A
- Postnasal drip, sinusitis A A
- Shortness of breath A A
- Repeated lung infections A A
- Foul-smelling, bulky greasy stools A A A
- Poor growth A
- Male infertility A
What are some diagnostic tests used to diagnose cystic fibros
A A A A A A A A A
is? - ---answers
A A -
ASweat test (measures the amount of chloride in sweat)
A A A A A A A A
, LATEST UPDATE WGU D027 ADVANCED PA A A A A A
THOPHARMACOLOGICAL FOUNDATIONS ( A A
ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A
- Genetic test (detects chromosomal mutations associated with
A A A A A A A
the disease)
A
What is an example of x-linked dominant disorder? - ---
A A A A A A A A A
answers
A -
Duchenne muscular dystrophy inheritance (DMD)
A A A A A
- Color blindness A
What is Duchenne Muscular Dystrophy? ----- answers
A A A A - X-A
linked dominant disorderA A
- Until recently, children with this order did not live beyond t
A A A A A A A A A A
heir teens A
- Life expectancy now 30's and some into their 40's to 50's
A A A A A A A A A A
- Affects the muscles, leading to muscle wasting that worsens
A A A A A A A A A
over time A
- Almost always affects boys and symptoms being early in
A A A A A A A A A
childhood
What are some signs and symptoms in patients with Duchenn
A A A A A A A A A
e Muscular Dystrophy? - ---answers ------------------ Difficulty
A A A A
standing up, walking, and climbing stairs
A A A A A
- May have heart and lung problems
A A A A A
- Scoliosis
