Questions And Correct Answers
Name the DNA binding vesicants - correct answers anthracyclines (-rubicins)
mechlorethamine
bendamustine
name the non-DNA binding vesicants - correct answers vinca alkaloids (vincristine, vinblastine,
vinorelbine, vindisine)
taxanes (paclitaxel, docetaxel)
which drug has an antidote if it causes extravasation? vincristine, 5FU, or cyclophosphamide - correct
answers vincristine
antidote for an anthracycline - correct answers dexarazoxane
how long do you have to administer dexarazoxane - correct answers within 6 hours
if a patient developed extravasation due to doxorubicin, where should dexarazoxane be injected? - correct
answers away from the site of extravasation
what dosages of dexarazoxane should be administered on D1,2,3 - correct answers D1: 1000
mg/m2
D2: 1000 mg/m2
D3: 500 mg/m2
what if the patients CrCl is 28, how does the dose of dexarazoxane change - correct
answers decrease each day by 50%