TEST BANK FOR ABRAMS' CLINICAL DRUG THERAPY:
RATIONALES FOR NURSING PRACTICE THIRTEENTH, NORTH
AMERICAN EDITION
BY GERALYN FRANDSEN EDD RN (AUTHOR), SANDRA
PENNINGTON
,Table of Contents
Chapter 1 The Foundation of Pharmacology: Quality and Safety ................................................................ 4
Chapter 2 Basic Concepts and Processes .................................................................................................... 16
Chapter 3 Medication Administration and the Nursing Process of Drug Therapy ..................................... 27
Chapter 4 Pharmacology and the Care of Infants and Pediatric Patients Medication Administration in .. 38
Chapter 5 Pharmacology and the Care of Adults and Geriatric Patients.................................................... 49
Chapter 6 Pharmacology and the Care of Pregnant or Lactating Woman ................................................. 60
Chapter 7 Pharmacology and Women's Health .......................................................................................... 70
Chapter 8 Pharmacology and Men's Health ............................................................................................... 70
Chapter 9 Drug Therapy for Coagulation Disorders.................................................................................... 71
Chapter 10 Drug Therapy for Dyslipidemia ................................................................................................ 82
Chapter 11 Drug Therapy for Hematopoietic Disorders ............................................................................. 93
Chapter 12 Drug Therapy: Immunizations ................................................................................................ 105
Chapter 13 Drug Therapy to Decrease Immunity ..................................................................................... 116
Chapter 14 Drug Therapy for the Treatment of Cancer ........................................................................... 127
Chapter 15 Inflammation, Infection, and the Use of Antimicrobial Agents ............................................. 139
Chapter 16 Drug Therapy to Decrease Pain, Fever, and Inflammation .................................................... 151
Chapter 17 Drug Therapy With Corticosteroids ....................................................................................... 161
Chapter 18 Drug Therapy With Beta-Lactam Antibacterial Agents .......................................................... 173
Chapter 19 Drug Therapy With Aminoglycosides and Fluoroquinolones ................................................. 184
Chapter 20 Drug Therapy With Tetracyclines, Sulfonamides, and Urinary Antiseptics ........................... 195
Chapter 21 Drug Therapy With Macrolides and Miscellaneous Anti-infective Agents ............................ 204
Chapter 22 Drug Therapy for Tuberculosis and Mycobacterium avium Complex Disease ...................... 215
Chapter 23 Drug Therapy for Viral Infections ........................................................................................... 227
Chapter 24 Drug Therapy for Fungal Infections........................................................................................ 238
Chapter 25 Drug Therapy for Parasitic Infections..................................................................................... 249
Chapter 26 Drug Therapy for Hypertension ............................................................................................. 260
Chapter 27 Drug Therapy for Dysrhythmias ............................................................................................. 271
Chapter 28 Drug Therapy for Coronary Heart Disease ............................................................................. 282
Chapter 29 Drug Therapy for Shock and Hypotension ............................................................................. 293
Chapter 30 Drug Therapy for Heart Failure .............................................................................................. 303
Chapter 31 Drug Therapy for Nasal Congestion and Cough ..................................................................... 315
Chapter 32 Drug Therapy to Decrease Histamine Effects and Allergic Response .................................... 327
,Chapter 33 Drug Therapy for Asthma and Bronchoconstriction .............................................................. 337
Chapter 34 Drug Therapy for Fluid Volume Excess................................................................................... 349
Chapter 35 Nutritional Support Products, Vitamins, and Mineral Supplements ..................................... 360
Chapter 36 Drug Therapy for Weight Management ................................................................................. 371
Chapter 37 Drug Therapy for Peptic Ulcer Disease and Hyperacidity ...................................................... 383
Chapter 38 Drug Therapy for Nausea and Vomiting................................................................................. 394
Chapter 39 Drug Therapy for Constipation and Elimination Problems .................................................... 404
Chapter 40 Drug Therapy for Diarrhea ..................................................................................................... 415
Chapter 41 Drug Therapy for Diabetes Mellitus ....................................................................................... 426
Chapter 42 Drug Therapy for Hyperthyroidism and Hypothyroidism ...................................................... 437
Chapter 43 Drug Therapy for Pituitary and Hypothalamic Dysfunction ................................................... 449
Chapter 44 Drug Therapy to Regulate Calcium and Bone Metabolism .................................................... 459
Chapter 45 Drug Therapy for Addison's Disease and Cushing's Disease .................................................. 470
Chapter 46 Physiology of the Autonomic and Central Nervous Systems and Indications for the Use of 479
Chapter 47 Drug Therapy for Myasthenia Gravis, Alzheimer's Disease, and Urinary Retention ............. 490
Chapter 48 Drug Therapy for Parkinson's Disease, Urinary Spasticity, and Disorders Requiring............. 502
Chapter 49 Drug Therapy With Opioids .................................................................................................... 513
Chapter 50 Drug Therapy With Local Anesthetics .................................................................................... 524
Chapter 51 Drug Therapy With General Anesthetics ............................................................................... 532
Chapter 52 Drug Therapy for Migraines and Other Headaches ............................................................... 539
Chapter 53 Drug Therapy for Seizure Disorders and Spasticity ................................................................ 549
Chapter 54 Drug Therapy for Anxiety and Insomnia ................................................................................ 559
Chapter 55 Drug Therapy for Depression and Mood Stabilization ........................................................... 570
Chapter 56 Drug Therapy for Psychotic Disorders .................................................................................... 583
Chapter 57 Drug Therapy for Attention Deficit Hyperactivity Disorder and Narcolepsy ......................... 594
Chapter 58 Drug Therapy for Substance Abuse Disorders ....................................................................... 606
Chapter 59 Drug Therapy for Disorders of the Eye................................................................................... 618
Chapter 60 Drug Therapy for Disorders of the Ear ................................................................................... 627
Chapter 61 Drug Therapy for Disorders of the Skin .................................................................................. 637
,TEST BANK FOR ABRAMS' CLINICAL DRUG THERAPY:
RATIONALES FOR NURSING PRACTICE THIRTEENTH, NORTH
AMERICAN EDITION
BY GERALYN FRANDSEN EDD RN (AUTHOR), SANDRA
PENNINGTON
Chapter 1 The Foundation of Pharmacology: Quality and Safety
1. A woman has been prescribed paroxetine hydrochloride, which is an antidepressant agent
administered in pill form. The medication is administered for her obsessive- compulsive disorder. This
medication will produce which of the following effects?
A) Curative
B) Systemic
C) Local
D) Parenteral
ANSWER>>> B
Feedback:
Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the body.
Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will control
the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intravenously.
,2. A patient has been prescribed an antibiotic. This medication is a naturally occurring substance
that has been chemically modified. What is another name for this type of
medication?
A) Synthetic drug
B) Semisynthetic drug
C) Biotechnology drug
D) Prototype drug
ANSWER>>> B
Feedback:
Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have been
chemically modified. Synthetic drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that can be inserted into living
organisms.
Prototype drugs are the first drug of a particular group to be developed.
3. A patient is administered morphine. Morphine is a prototypical drug that can be classified in
different ways. Which of the following classifications applies to morphine?
A) Central nervous system depressant
B) Central nervous system stimulant
C) Anti-inflammatory
D) Antihypertensive
ANSWER>>> A
Feedback:
, Drugs are classified according to their effects on particular body systems, their therapeutic uses,
and their chemical characteristics. For example, morphine can be classified as a central nervous system
depressant and a narcotic or opioid analgesic. A central nervous system stimulant increases attention
and raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or joint
inflammation. An antihypertensive agent reduces blood pressure.
4. A patient is administered amoxicillin (Amoxil). The generic name of this
medication indicates that it belongs to which drug group?
A) Selective serotonin reuptake inhibitors
B) Diuretics
C) Penicillins
D) ACE inhibitors
ANSWER>>> C
Feedback:
The generic name often indicates the drug group (e.g., drugs with generic names ending in
―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications that have
antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medications that
increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor is the broad
classification for the angiotensin-converting enzyme inhibitors, not the generic name.
5. The administration of diphenhydramine (Benadryl), which is an over-the-counter medication, is
regulated by which government
agency?
A) Public Health Service
B) Federal Trade Commission
C) Occupational Safety and Health
Administration
, D) Food and Drug Administration
ANSWER>>> D
Feedback:
The Food and Drug Administration approves drugs for over-the-counter availability, including
the transfer of drugs from prescription to OTC status, and may require clinical trials to determine the
safety and effectiveness of OTC use. The Public Health Service is regulated by the state to maintain the
health of individual citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation.
The Occupational Safety and Health Administration regulates safety within the workplace.
6. The administration of anabolic steroids is
regulated by which of the following laws?
A) The Food, Drug, and Cosmetic Act of 1938
B) The Comprehensive Drug Abuse Prevention and Control Act
C) The Harrison Narcotic Act
D) The Shirley Amendment
ANSWER>>> B
Feedback:
The Comprehensive Drug Abuse Prevention and Control Act regulates the manufacture and
distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids. The Food, Drug,
and Cosmetic Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA
control over drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics.
The Shirley Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
7. A nurse is responsible for maintaining an accurate count and record of the controlled substances
on the nursing unit. This nursing action is regulated by which of the following
RATIONALES FOR NURSING PRACTICE THIRTEENTH, NORTH
AMERICAN EDITION
BY GERALYN FRANDSEN EDD RN (AUTHOR), SANDRA
PENNINGTON
,Table of Contents
Chapter 1 The Foundation of Pharmacology: Quality and Safety ................................................................ 4
Chapter 2 Basic Concepts and Processes .................................................................................................... 16
Chapter 3 Medication Administration and the Nursing Process of Drug Therapy ..................................... 27
Chapter 4 Pharmacology and the Care of Infants and Pediatric Patients Medication Administration in .. 38
Chapter 5 Pharmacology and the Care of Adults and Geriatric Patients.................................................... 49
Chapter 6 Pharmacology and the Care of Pregnant or Lactating Woman ................................................. 60
Chapter 7 Pharmacology and Women's Health .......................................................................................... 70
Chapter 8 Pharmacology and Men's Health ............................................................................................... 70
Chapter 9 Drug Therapy for Coagulation Disorders.................................................................................... 71
Chapter 10 Drug Therapy for Dyslipidemia ................................................................................................ 82
Chapter 11 Drug Therapy for Hematopoietic Disorders ............................................................................. 93
Chapter 12 Drug Therapy: Immunizations ................................................................................................ 105
Chapter 13 Drug Therapy to Decrease Immunity ..................................................................................... 116
Chapter 14 Drug Therapy for the Treatment of Cancer ........................................................................... 127
Chapter 15 Inflammation, Infection, and the Use of Antimicrobial Agents ............................................. 139
Chapter 16 Drug Therapy to Decrease Pain, Fever, and Inflammation .................................................... 151
Chapter 17 Drug Therapy With Corticosteroids ....................................................................................... 161
Chapter 18 Drug Therapy With Beta-Lactam Antibacterial Agents .......................................................... 173
Chapter 19 Drug Therapy With Aminoglycosides and Fluoroquinolones ................................................. 184
Chapter 20 Drug Therapy With Tetracyclines, Sulfonamides, and Urinary Antiseptics ........................... 195
Chapter 21 Drug Therapy With Macrolides and Miscellaneous Anti-infective Agents ............................ 204
Chapter 22 Drug Therapy for Tuberculosis and Mycobacterium avium Complex Disease ...................... 215
Chapter 23 Drug Therapy for Viral Infections ........................................................................................... 227
Chapter 24 Drug Therapy for Fungal Infections........................................................................................ 238
Chapter 25 Drug Therapy for Parasitic Infections..................................................................................... 249
Chapter 26 Drug Therapy for Hypertension ............................................................................................. 260
Chapter 27 Drug Therapy for Dysrhythmias ............................................................................................. 271
Chapter 28 Drug Therapy for Coronary Heart Disease ............................................................................. 282
Chapter 29 Drug Therapy for Shock and Hypotension ............................................................................. 293
Chapter 30 Drug Therapy for Heart Failure .............................................................................................. 303
Chapter 31 Drug Therapy for Nasal Congestion and Cough ..................................................................... 315
Chapter 32 Drug Therapy to Decrease Histamine Effects and Allergic Response .................................... 327
,Chapter 33 Drug Therapy for Asthma and Bronchoconstriction .............................................................. 337
Chapter 34 Drug Therapy for Fluid Volume Excess................................................................................... 349
Chapter 35 Nutritional Support Products, Vitamins, and Mineral Supplements ..................................... 360
Chapter 36 Drug Therapy for Weight Management ................................................................................. 371
Chapter 37 Drug Therapy for Peptic Ulcer Disease and Hyperacidity ...................................................... 383
Chapter 38 Drug Therapy for Nausea and Vomiting................................................................................. 394
Chapter 39 Drug Therapy for Constipation and Elimination Problems .................................................... 404
Chapter 40 Drug Therapy for Diarrhea ..................................................................................................... 415
Chapter 41 Drug Therapy for Diabetes Mellitus ....................................................................................... 426
Chapter 42 Drug Therapy for Hyperthyroidism and Hypothyroidism ...................................................... 437
Chapter 43 Drug Therapy for Pituitary and Hypothalamic Dysfunction ................................................... 449
Chapter 44 Drug Therapy to Regulate Calcium and Bone Metabolism .................................................... 459
Chapter 45 Drug Therapy for Addison's Disease and Cushing's Disease .................................................. 470
Chapter 46 Physiology of the Autonomic and Central Nervous Systems and Indications for the Use of 479
Chapter 47 Drug Therapy for Myasthenia Gravis, Alzheimer's Disease, and Urinary Retention ............. 490
Chapter 48 Drug Therapy for Parkinson's Disease, Urinary Spasticity, and Disorders Requiring............. 502
Chapter 49 Drug Therapy With Opioids .................................................................................................... 513
Chapter 50 Drug Therapy With Local Anesthetics .................................................................................... 524
Chapter 51 Drug Therapy With General Anesthetics ............................................................................... 532
Chapter 52 Drug Therapy for Migraines and Other Headaches ............................................................... 539
Chapter 53 Drug Therapy for Seizure Disorders and Spasticity ................................................................ 549
Chapter 54 Drug Therapy for Anxiety and Insomnia ................................................................................ 559
Chapter 55 Drug Therapy for Depression and Mood Stabilization ........................................................... 570
Chapter 56 Drug Therapy for Psychotic Disorders .................................................................................... 583
Chapter 57 Drug Therapy for Attention Deficit Hyperactivity Disorder and Narcolepsy ......................... 594
Chapter 58 Drug Therapy for Substance Abuse Disorders ....................................................................... 606
Chapter 59 Drug Therapy for Disorders of the Eye................................................................................... 618
Chapter 60 Drug Therapy for Disorders of the Ear ................................................................................... 627
Chapter 61 Drug Therapy for Disorders of the Skin .................................................................................. 637
,TEST BANK FOR ABRAMS' CLINICAL DRUG THERAPY:
RATIONALES FOR NURSING PRACTICE THIRTEENTH, NORTH
AMERICAN EDITION
BY GERALYN FRANDSEN EDD RN (AUTHOR), SANDRA
PENNINGTON
Chapter 1 The Foundation of Pharmacology: Quality and Safety
1. A woman has been prescribed paroxetine hydrochloride, which is an antidepressant agent
administered in pill form. The medication is administered for her obsessive- compulsive disorder. This
medication will produce which of the following effects?
A) Curative
B) Systemic
C) Local
D) Parenteral
ANSWER>>> B
Feedback:
Drugs that produce systemic effects are taken into the body, circulated through the
bloodstream to their sites of action in various body tissues, and eventually eliminated from the body.
Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride will control
the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or intravenously.
,2. A patient has been prescribed an antibiotic. This medication is a naturally occurring substance
that has been chemically modified. What is another name for this type of
medication?
A) Synthetic drug
B) Semisynthetic drug
C) Biotechnology drug
D) Prototype drug
ANSWER>>> B
Feedback:
Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have been
chemically modified. Synthetic drugs are more standardized in their chemical characteristics, more
consistent in their effects, and less likely to produce allergic reactions. Biotechnology drugs involve
manipulating DNA and RNA and recombining genes into hybrid molecules that can be inserted into living
organisms.
Prototype drugs are the first drug of a particular group to be developed.
3. A patient is administered morphine. Morphine is a prototypical drug that can be classified in
different ways. Which of the following classifications applies to morphine?
A) Central nervous system depressant
B) Central nervous system stimulant
C) Anti-inflammatory
D) Antihypertensive
ANSWER>>> A
Feedback:
, Drugs are classified according to their effects on particular body systems, their therapeutic uses,
and their chemical characteristics. For example, morphine can be classified as a central nervous system
depressant and a narcotic or opioid analgesic. A central nervous system stimulant increases attention
and raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or joint
inflammation. An antihypertensive agent reduces blood pressure.
4. A patient is administered amoxicillin (Amoxil). The generic name of this
medication indicates that it belongs to which drug group?
A) Selective serotonin reuptake inhibitors
B) Diuretics
C) Penicillins
D) ACE inhibitors
ANSWER>>> C
Feedback:
The generic name often indicates the drug group (e.g., drugs with generic names ending in
―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications that have
antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medications that
increase urine output; diuretic is a broad classification, not a generic name. ACE inhibitor is the broad
classification for the angiotensin-converting enzyme inhibitors, not the generic name.
5. The administration of diphenhydramine (Benadryl), which is an over-the-counter medication, is
regulated by which government
agency?
A) Public Health Service
B) Federal Trade Commission
C) Occupational Safety and Health
Administration
, D) Food and Drug Administration
ANSWER>>> D
Feedback:
The Food and Drug Administration approves drugs for over-the-counter availability, including
the transfer of drugs from prescription to OTC status, and may require clinical trials to determine the
safety and effectiveness of OTC use. The Public Health Service is regulated by the state to maintain the
health of individual citizens of the state. The Federal Trade Commission regulates imports and exports
throughout the nation.
The Occupational Safety and Health Administration regulates safety within the workplace.
6. The administration of anabolic steroids is
regulated by which of the following laws?
A) The Food, Drug, and Cosmetic Act of 1938
B) The Comprehensive Drug Abuse Prevention and Control Act
C) The Harrison Narcotic Act
D) The Shirley Amendment
ANSWER>>> B
Feedback:
The Comprehensive Drug Abuse Prevention and Control Act regulates the manufacture and
distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids. The Food, Drug,
and Cosmetic Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA
control over drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale, and
use of opium, cocaine, marijuana, and other drugs that the act defined as narcotics.
The Shirley Amendment of 1912 prohibited fraudulent claims of drug effectiveness.
7. A nurse is responsible for maintaining an accurate count and record of the controlled substances
on the nursing unit. This nursing action is regulated by which of the following
