REJECTION EXAM 2025 QUESTIONS
AND ANSWERS
The immune system recognizes the antigens of the new organ as... - ANS non-self
Auto-transplantation is... - ANS transplantation of self tissue.
Not detected as a foreign body, no rejection. Ex. Own blood before surgery
Iso-transplantation is... - ANS transplantation of tissue or organ between genetically identical
individuals.
Doesn't activate immune response.
Allotransplantation is... - ANS transplantation between genetically different people.
This will trigger the immune response. Allograft.
Xenotransplantation is... - ANS transplant between two different species.
The immune system protects us through... - ANS Surveillance
Defense
Homeostasis
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, A humoral response involves... - ANS the production of antibodies (immunoglobulins) by
plasma cells (B-cells)
A cellular response is... - ANS communication between cells (lymphocytes). This leads to
intracellular destruction of foreign cells (T-cells)
Lymphocytes include... - ANS T cells
B cells
T cells are involved in the... - ANS cell-mediated immunity, therefore responsible for cellular
rejection
Immature lymphocytes migrate through thymus to mature
Differentiate to memory cells, cytotoxic cells, helper cells, suppressor cells
B cells are involved in the... - ANS humoral immune response, therefore responsible for
humoral rejection (AMR)
Immature lymphocytes migrate through bone marrow to mature
Differentiate to memory cells, IgM, IgG, IgA, IgE (plasma cells)
Characteristics of the immune system: - ANS Ability to recognize and eliminate foreign
antigens
Capacity for immunologic memory
Distinct antigen specificities after immunizations
Tolerance of self antigens
Cytokines are characterized as... - ANS hormonal messengers
Tells cells to proliferate in response to foreign cells
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