NSG 6005 Advanced Pharmacology FL02 Week 6 Discussion 2 / Discussion 1 Completed A

NSG 6005 Advanced Pharmacology FL02 Week 6 Discussion 2 / Discussion 1 Discussion 1 There aren't any reliable differentiating signs or symptoms; functional heartburn denotes endoscopy-negative heartburn. A normal esophageal pH study differentiates between nonerosive GERD and functional heartburn. An alternative is a normal impedance-pH study. These studies would usually be done in patients who fail to respond to proton-pump inhibitor (PPI) therapy. Referral to a gastroenterologist to diagnose and treat GERD is necessary as well (Woo, & 2015). A short trial 8 weeks of PPIs and lifestyle therapy such as weight loss if needed, and elevation of the head off the bed for nocturnal features should be initiated. Medications include a standard-dose proton-pump inhibitor, omeprazole: 20 mg orally once daily, omeprazole/sodium bicarbonate: 20/1100 mg to 40/1100 mg (capsule) orally once daily; or 20/1680 mg to 40/1680 mg (powder) orally once daily. Esomeprazole: 20-40 mg orally once daily, rabeprazole: 20 mg orally once daily, pantoprazole: 40 mg orally once daily, lansoprazole: 15-30 mg orally once daily and dexlansoprazole: 30-60 mg orally once daily (Woo, & 2015). Lifestyle adjustments are weight loss for overweight people; head-of-bed elevation; and avoidance of late-night eating if nocturnal symptoms are present. Specific food eliminations example chocolate, caffeine, alcohol, acidic and/or spicy foods are not routinely required unless individual tailoring seems to be beneficial. Maintenance PPI therapy is recommended for those who have symptoms when the PPI is discontinued, as well as for those with erosive esophagitis and Barrett's esophagus. Most people will relapse off PPI therapy (Woo, & 2015). Reference Woo, T. M., & Robinson, M. V. (2015). Pharmacotherapeutics for advanced practice nurse prescribers. FA Davis. Discussion 2 There aren't any reliable differentiating signs or symptoms; functional heartburn denotes endoscopy-negative heartburn. A normal esophageal pH study differentiates between nonerosive GERD and functional heartburn. An alternative is a normal impedance-pH study. These studies would usually be done in patients who fail to respond to proton-pump inhibitor (PPI) therapy. Referral to a gastroenterologist to diagnose and treat GERD is necessary as well (Woo, & 2015). A short trial 8 weeks of PPIs and lifestyle therapy such as weight loss if needed, and elevation of the head off the bed for nocturnal features should be initiated. Medications include a standard-dose proton-pump inhibitor, omeprazole: 20 mg orally once daily, omeprazole/sodium bicarbonate: 20/1100 mg to 40/1100 mg (capsule) orally once daily; or 20/1680 mg to 40/1680 mg (powder) orally once daily. Esomeprazole: 20-40 mg orally once daily, rabeprazole: 20 mg orally once daily, pantoprazole: 40 mg orally once daily, lansoprazole: 15-30 mg orally once daily and dexlansoprazole: 30-60 mg orally once daily (Woo, & 2015). Lifestyle adjustments are weight loss for overweight people; head-of-bed elevation; and avoidance of late-night eating if nocturnal symptoms are present. Specific food eliminations example chocolate, caffeine, alcohol, acidic and/or spicy foods are not routinely required unless individual tailoring seems to be beneficial. Maintenance PPI therapy is recommended for those who have symptoms when the PPI is discontinued, as well as for those with erosive esophagitis and Barrett's esophagus. Most people will relapse off PPI therapy (Woo, & 2015). Reference Woo, T. M., & Robinson, M. V. (2015). Pharmacotherapeutics for advanced practice nurse prescribers. FA Davis.