1
NSG 552 PSYCHOPHARMACOLOGY EXAM 1 -
MODULES 1-3 2025
WITH 100% CORRECT ANSWERS.
FGA - which come in long-acting injectables: correct answers
Fluphenazine/Prolixin
Haloperidol/Haldol
SGA - which come in long-acting injectables: correct answers
Risperidone/Risperdal
Paliperidone/Invega
Aripiprazole/Abilify
Olanzapine/Zyprexa
SGA associated with greatest prolactin elevation: correct answers Risperdal
Weight neutral SGAs: correct answers ziprasidone, abilify. (latuda?)
Only SGA shown shown to decrease SI risks: correct answers Clozapine
SGA assocaited with agranulocytosis and 30-80% sialorrhea: correct answers
Clozapine
,2
Clozapine treatment should be interrupted when ANC is below: correct answers
1000
T/F: Patients started on Clozapine need to be registered in the Clozapine REMS
system correct answers T
A patient newly started on Clozapine will require ANC Monitoring __________ x
___________ months correct answers Weekly for 6 months
Parameters that require monitoring at baseline and ongoing once a patient is
started on an SGA: correct answers Weight, BMI, BP, FBG/AIC, FLP
Symptoms of gynecomastia, erectile dysfunction, galactorrhea, absence of
menses, are all indicative of D2 blockade in the ________________ pathway and
suggestive of _______________. correct answers Tuberoinfundibular, hyper-
prolactin
When should a provider consider a long-acting antipsychotic injectables? correct
answers
Blackbox warning assocaited with antipsychotic use in dementia
________________________? correct answers increased risk of death and CVA
events
_________________ may occur when stopping or reducing an antipsychotic
medication. What are the characteristics? correct answers WIthdrawal. N/V/D
, 3
Antipsychotic is helpful and improve symptoms of Tardive Dyskinesia: correct
answers clozaril
The primary managment of patients who experience tardive dyskinesia: correct
answers Limiting drug exposure, stopping antipsychotic (with slow taper), or
switching to an SGA like clozapril or quetiapine. Tetrabenazine or other VMAT2
inhibitor. Amantadine, benzos, beta blockers, levitracitam,
In obese patients seeking antipsychotic medications, the clinician should avoid
medications that blocks: correct answers HT2C and 5-HT1A receptors, histamine
H1 receptor and dopamine D2 receptor among others. Antipsychotics differ in
their ability to block these receptors and this partly explains their different liability
to cause weight gain. Both olanzapine and clozapine, drugs with a high risk of
weight gain, bind strongly to the histamine H1 and serotonin 5-HT2C receptors.
Antipsychotics must occupy more than _______% of _____________ receptors to
cause EPS: correct answers 75-80% of D2 receptors
Auto-induction: correct answers occurs when a drug produces enymes that are
responsible for its own metabolism
anticonvulsant: correct answers a drug used to treat epileptic fits and other
convulsant disorders
NSG 552 PSYCHOPHARMACOLOGY EXAM 1 -
MODULES 1-3 2025
WITH 100% CORRECT ANSWERS.
FGA - which come in long-acting injectables: correct answers
Fluphenazine/Prolixin
Haloperidol/Haldol
SGA - which come in long-acting injectables: correct answers
Risperidone/Risperdal
Paliperidone/Invega
Aripiprazole/Abilify
Olanzapine/Zyprexa
SGA associated with greatest prolactin elevation: correct answers Risperdal
Weight neutral SGAs: correct answers ziprasidone, abilify. (latuda?)
Only SGA shown shown to decrease SI risks: correct answers Clozapine
SGA assocaited with agranulocytosis and 30-80% sialorrhea: correct answers
Clozapine
,2
Clozapine treatment should be interrupted when ANC is below: correct answers
1000
T/F: Patients started on Clozapine need to be registered in the Clozapine REMS
system correct answers T
A patient newly started on Clozapine will require ANC Monitoring __________ x
___________ months correct answers Weekly for 6 months
Parameters that require monitoring at baseline and ongoing once a patient is
started on an SGA: correct answers Weight, BMI, BP, FBG/AIC, FLP
Symptoms of gynecomastia, erectile dysfunction, galactorrhea, absence of
menses, are all indicative of D2 blockade in the ________________ pathway and
suggestive of _______________. correct answers Tuberoinfundibular, hyper-
prolactin
When should a provider consider a long-acting antipsychotic injectables? correct
answers
Blackbox warning assocaited with antipsychotic use in dementia
________________________? correct answers increased risk of death and CVA
events
_________________ may occur when stopping or reducing an antipsychotic
medication. What are the characteristics? correct answers WIthdrawal. N/V/D
, 3
Antipsychotic is helpful and improve symptoms of Tardive Dyskinesia: correct
answers clozaril
The primary managment of patients who experience tardive dyskinesia: correct
answers Limiting drug exposure, stopping antipsychotic (with slow taper), or
switching to an SGA like clozapril or quetiapine. Tetrabenazine or other VMAT2
inhibitor. Amantadine, benzos, beta blockers, levitracitam,
In obese patients seeking antipsychotic medications, the clinician should avoid
medications that blocks: correct answers HT2C and 5-HT1A receptors, histamine
H1 receptor and dopamine D2 receptor among others. Antipsychotics differ in
their ability to block these receptors and this partly explains their different liability
to cause weight gain. Both olanzapine and clozapine, drugs with a high risk of
weight gain, bind strongly to the histamine H1 and serotonin 5-HT2C receptors.
Antipsychotics must occupy more than _______% of _____________ receptors to
cause EPS: correct answers 75-80% of D2 receptors
Auto-induction: correct answers occurs when a drug produces enymes that are
responsible for its own metabolism
anticonvulsant: correct answers a drug used to treat epileptic fits and other
convulsant disorders
