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"On-off" phenomenon
- answer-Rapid swings in response to levodopa
PD worsens when too little dopamine
Dyskinesia occurs with too much dopamine
Acetaminophen antidote
- answer-Acetylcysyeine regimen
Acetaminophen overdose
- answer-Lethal when overdose: hepatotoxicity
Long term ingestion of large doses: nephropathy
Acetylcholine
- answer-ACh
Causes bronchial constriction and narrowing of the airways
ADHD medications
- answer-Amphetamine (dexedrine, adderall)
Methylphenidate (concerta, ritalin, metagate CD)
Atomoxtine (strattera)
Adjuvant drugs
- answer-Assist primary drugs in relieving pain
-NSAIDs
-Antidepressants
-Anticonvulsants
-Corticosteroids
Adjuvant drugs for neuropathic pain
- answer-Amitriptyline (antidepressant)
Gabapentin or pregabalin (anticonvulsants)
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,Adrenergics: Sympathomimetics
- answer-Used for nasal congestion
-Constrict small blood vessels, nasal secretions in swollen mucous membranes are
better able to drain
Adverse consequences of histamine stimulation
- answer-Vasodilation
Increased GI and respiratory secretions
Increased capillary permeability
Adverse effects of ADHD meds
- answer-Palpitations
Tachycardia
Hypertension
Angina
Dysrhythmias
Nervousness
Restlessness
Anxiety
Insomnia
Nausea
Vomiting
Diarrhea
Dry mouth
Increased urinary frequency
Adverse effects of anorxiants
- answer-Elevated BP
Palpitations
Anxiety
Agitation
Dizziness
Headache
Adverse effects of antiepileptic drugs
- answer-Black box warning: suicidal thoughts and behavior
Mental status change
Mood change
Change in LOC or sensorium
Eye problems
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,Visual disorders
Sore throat
Fever
Adverse effects of antifibrinolytic drugs
- answer-Uncommon and mild
Dysrhythmia
Orthostatic hypotension
Bradycardia
Headache
Dizziness
Fatigue
Nausea
Vomiting
Abdominal cramps
Diarrhea
Adverse effects of antihistamines
- answer-Anticholinergic (drying) effects are most common
-Dry mouth
-Difficulty urinating
-Constipation
-Changes in vision
Also drowsiness: mild to deep sleep
Adverse effects of antitussives
- answer-Dizziness, drowsiness, nausea
Benzonatate: Headache
Opioids: vomiting, constipation
Adverse effects of anxiolytic drugs
- answer-Decreased CNS activity
Sedation
Hypotension
Drowsiness
Loss of coordination
Dizziness
Headaches
Nausea
Vomiting
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, Dry mouth
Constipation
Adverse effects of buspirone
- answer-Paradoxical anxiety
Blurred vision
Headache
Nausea
Adverse effects of carbidopa-levodopa
- answer-Cardiac dysrhythmias
Hypotension
Chorea
Muscle cramps
GI stress
Adverse effects of iron
- answer-Most common cause of pediatric poisoning deaths
Nausea
Vomiting
Diarrhea
Constipation
Stomach cramps/pain
Black, tarry stools
Adverse effects of lithium
- answer-Toxicity:
-GI discomfort
-Tremor
-Confusion
-Somnolence
-Seizure
-Cardiac dysrhythmia
-Possible death
Other:
-Drowsiness
-Slurred speech
-Choreoathetotic movement
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