WGU D027 OA EXAM
2025/2026 ACTUAL EXAM TEST BANK 100 QUESTION AND
CORRECT DETAILED ANSWERS WITH
RATIONALES|AGRADE
1. What is the gold standard for the suspected diagnosis of Celiac Disease?-
Ans>> : Endoscopy with small intestine biopsy
2. A 44-year-old woman has recently been diagnosed with advanced metasta-
tic non-small-cell lung cancer. Genetic testing is ordered to determine if the
patient's tumor has any genomic alterations and to guide treatment decisions.
A few weeks later, the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this information,
what type of genetic mutation does this patient have?
Ans>>: EGFR mutation
3. A 20-year-old male meets with an advanced professional nurse (APN) to
discuss symptoms that have been slowly progressing over the past several
years. He is mainly concerned because he has been falling frequently. Since
childhood, his gait has consisted of walking on his toes. During middle school,
he was able to participate in sports but was unable to participate in high
school sports due to difficulty with running and jumping. Lately, he has
noticed it takes longer and is more difficult to change positions from sitting to
standing than it used to in the past. He has also been waking up with muscle
and joint stiffness. The APRN notes that his family history is not significant
for any chronic or genetic diseases. Which condition is likely to be the cause
,of these symptoms?
Ans>>: Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular
dystrophy, a genetic disorder that gradually makes the body's muscles weaker and
smaller. It causes less severe problems than the most common type, Duchenne
muscular dystrophy.
4. Which statement should the provider give the patient regarding the patho-
physiology of SLE and its relation to thrombocytopenia?
Ans>>: SLE disrupts immune homeostasis and promotes development of self-
reactive antibodies.
5. A female patient presents to an office to establish care. Her previous pri-
mary care provider told her to follow up regarding an elevated ferritin level.
She has no previous medical history and is currently asymptomatic. She is
concerned about the elevated ferritin and would like to know if she should
be worried. What should the provider do next for this patient?
Ans>>: Order a liver function test
6. A 75-year-old female presents to the emergency department with an irreg-
ular heart rate of 130.What can be ascertained about this patient's findings
given the limited information?
Ans>>: She is diagnosed with atrial fibrillation and needs her heart rate controlled
with metoprolol (Lopressor).
7. Which condition from this patient's medical history is contributing to the
loss of contractility?
Ans>>: Acute myocardial infarction
,8. Which condition is this patient suffering from?
Ans>>: Diabetic ketoacidosis
9. A 45-year-old female fears that she is having a stroke and takes herself to
an emergency room. After several diagnostic and laboratory tests, the patient
is diagnosed with Cushing disease. Which lab abnormality would be present
in this patient?
Ans>>: Increased cortisol
10. SOB when lying down, and moving around --Based on the patient's pre-
sentation, which disease process is the patient likely exhibiting?
Ans>>: Asthma
11. A two-year-old child presents with a clear runny nose and cough which
has lasted 3 days. The child's mother reports the cough sounds like a barking
noise. The child is sleeping in the mother's arms and appears to have stridor.
The child's mother also reports an axillary temperature of 101°F last night.
Which management technique is appropriate for this child's symptoms?
Ans>>: Oral steroids and breathing treatments
12. Delerium, urinary incontinence, fever-- Which lab and diagnostic tests
should be ordered as part of the patient's assessment?: Complete blood count,
complete metabolic profile, and urinalysis
13. An 18-year-old male is involved in a motorcycle crash while not wearing a
helmet. He is brought into an emergency room and is immediately taken for
a CT scan. The provider tells the patient's parents he has bleeding between
the dura mater and the skull. What is this patient's condition called?
Ans>>: Epidural hematoma
14. -- What is the appropriate diagnosis for this patient?
Ans>>: Crohn's disease
15. Which diagnostic test is appropriate to order for this patient?
, Ans>>: Ultrasound
16. A 45-year-old male is being seen in the clinic for a yearly check-up and
lab work. His history includes hypertension and hyperlipidemia for which he
currently takes Norvasc 5 mg daily and Lipitor 20 mg nightly. Patient has a
family history of diabetes, hypertension, heart disease, and hyperlipidemia.
After obtaining lab work, the provider notices the patient's hgbA1c is elevated
at 7.5. The patient is already on a DASH diet and watching the amount of sweets
and carbohydrates he eats daily. The patient is not overweight and participates
in moderate physical activity at least 4-5 days a week. He was started on
Metformin three months ago, and his hemoglobin A1c is now 6.9. The nurse
expects to see a class of medication prescribed which is proven to reduce the
risk of cardiovascular events. Considering the treatment guidelines from the
American College of Cardiology, which medication should be recommended
for this patien
Ans>>: Invokana 100 mg daily
--Invokana is a medication used to treat type 2 diabetes. I t is a third-line medication
l l l l
2025/2026 ACTUAL EXAM TEST BANK 100 QUESTION AND
CORRECT DETAILED ANSWERS WITH
RATIONALES|AGRADE
1. What is the gold standard for the suspected diagnosis of Celiac Disease?-
Ans>> : Endoscopy with small intestine biopsy
2. A 44-year-old woman has recently been diagnosed with advanced metasta-
tic non-small-cell lung cancer. Genetic testing is ordered to determine if the
patient's tumor has any genomic alterations and to guide treatment decisions.
A few weeks later, the patient's test results come back positive for a genetic
mutation. The APN starts osimertinib (Tagrisso). Based on this information,
what type of genetic mutation does this patient have?
Ans>>: EGFR mutation
3. A 20-year-old male meets with an advanced professional nurse (APN) to
discuss symptoms that have been slowly progressing over the past several
years. He is mainly concerned because he has been falling frequently. Since
childhood, his gait has consisted of walking on his toes. During middle school,
he was able to participate in sports but was unable to participate in high
school sports due to difficulty with running and jumping. Lately, he has
noticed it takes longer and is more difficult to change positions from sitting to
standing than it used to in the past. He has also been waking up with muscle
and joint stiffness. The APRN notes that his family history is not significant
for any chronic or genetic diseases. Which condition is likely to be the cause
,of these symptoms?
Ans>>: Becker muscular dystrophy
--Becker muscular dystrophy (often called Becker MD or BMD) is a form of muscular
dystrophy, a genetic disorder that gradually makes the body's muscles weaker and
smaller. It causes less severe problems than the most common type, Duchenne
muscular dystrophy.
4. Which statement should the provider give the patient regarding the patho-
physiology of SLE and its relation to thrombocytopenia?
Ans>>: SLE disrupts immune homeostasis and promotes development of self-
reactive antibodies.
5. A female patient presents to an office to establish care. Her previous pri-
mary care provider told her to follow up regarding an elevated ferritin level.
She has no previous medical history and is currently asymptomatic. She is
concerned about the elevated ferritin and would like to know if she should
be worried. What should the provider do next for this patient?
Ans>>: Order a liver function test
6. A 75-year-old female presents to the emergency department with an irreg-
ular heart rate of 130.What can be ascertained about this patient's findings
given the limited information?
Ans>>: She is diagnosed with atrial fibrillation and needs her heart rate controlled
with metoprolol (Lopressor).
7. Which condition from this patient's medical history is contributing to the
loss of contractility?
Ans>>: Acute myocardial infarction
,8. Which condition is this patient suffering from?
Ans>>: Diabetic ketoacidosis
9. A 45-year-old female fears that she is having a stroke and takes herself to
an emergency room. After several diagnostic and laboratory tests, the patient
is diagnosed with Cushing disease. Which lab abnormality would be present
in this patient?
Ans>>: Increased cortisol
10. SOB when lying down, and moving around --Based on the patient's pre-
sentation, which disease process is the patient likely exhibiting?
Ans>>: Asthma
11. A two-year-old child presents with a clear runny nose and cough which
has lasted 3 days. The child's mother reports the cough sounds like a barking
noise. The child is sleeping in the mother's arms and appears to have stridor.
The child's mother also reports an axillary temperature of 101°F last night.
Which management technique is appropriate for this child's symptoms?
Ans>>: Oral steroids and breathing treatments
12. Delerium, urinary incontinence, fever-- Which lab and diagnostic tests
should be ordered as part of the patient's assessment?: Complete blood count,
complete metabolic profile, and urinalysis
13. An 18-year-old male is involved in a motorcycle crash while not wearing a
helmet. He is brought into an emergency room and is immediately taken for
a CT scan. The provider tells the patient's parents he has bleeding between
the dura mater and the skull. What is this patient's condition called?
Ans>>: Epidural hematoma
14. -- What is the appropriate diagnosis for this patient?
Ans>>: Crohn's disease
15. Which diagnostic test is appropriate to order for this patient?
, Ans>>: Ultrasound
16. A 45-year-old male is being seen in the clinic for a yearly check-up and
lab work. His history includes hypertension and hyperlipidemia for which he
currently takes Norvasc 5 mg daily and Lipitor 20 mg nightly. Patient has a
family history of diabetes, hypertension, heart disease, and hyperlipidemia.
After obtaining lab work, the provider notices the patient's hgbA1c is elevated
at 7.5. The patient is already on a DASH diet and watching the amount of sweets
and carbohydrates he eats daily. The patient is not overweight and participates
in moderate physical activity at least 4-5 days a week. He was started on
Metformin three months ago, and his hemoglobin A1c is now 6.9. The nurse
expects to see a class of medication prescribed which is proven to reduce the
risk of cardiovascular events. Considering the treatment guidelines from the
American College of Cardiology, which medication should be recommended
for this patien
Ans>>: Invokana 100 mg daily
--Invokana is a medication used to treat type 2 diabetes. I t is a third-line medication
l l l l
