HESI Exit Exam 2025: 750
NCLEX-Style RN Practice
Questions with Comprehensive
Rationales
Prepared for Nursing Students
July 10, 2025
Contents
1 Introduction 1
2 Practice Questions and Rationales 1
3 Conclusion 9
1
, 1 Introduction
This document provides a focused set of 100 NCLEX-style practice questions with clear,
concise rationales for the HESI Exit Exam 2025, representing a subset of the 750 questions
referenced in the title. Designed for nursing students, the content emphasizes critical
thinking and clinical decision-making, aligned with NCLEX-RN competencies, without
unnecessary complexity.
2 Practice Questions and Rationales
Question 1: What should a nurse monitor in a client receiving furosemide for heart
failure?
Answer: Serum potassium levels.
Rationale: Furosemide, a loop diuretic, can cause hypokalemia, increasing the
risk of arrhythmias in heart failure clients.
Question 2: What is the priority action for a client with an anaphylactic reaction?
Answer: Administer epinephrine.
Rationale: Epinephrine reverses anaphylaxis by constricting blood vessels and
opening airways, addressing life-threatening symptoms.
Question 3: A diabetic client reports shakiness. What is the nurses first action?
Answer: Check blood glucose levels.
Rationale: Shakiness may indicate hypoglycemia, and glucose levels guide appro-
priate treatment.
Question 4: What is the primary cause of hospital-acquired infections?
Answer: Poor hand hygiene.
Rationale: Proper hand hygiene is the most effective way to prevent pathogen
transmission in healthcare settings.
Question 5: What lab value should a nurse monitor for a client on heparin?
Answer: Activated partial thromboplastin time (aPTT).
Rationale: aPTT assesses heparins anticoagulant effect, ensuring therapeutic lev-
els without bleeding risks.
Question 6: What is the priority for a client with a new tracheostomy?
Answer: Ensure airway patency.
Rationale: Maintaining a clear airway prevents respiratory distress in tracheostomy
clients.
Question 7: A client with pneumonia has a fever of 101řF. What should the nurse
do?
Answer: Administer prescribed antipyretics.
Rationale: Antipyretics reduce fever, improving comfort and preventing compli-
cations like seizures.
Question 8: What is a hallmark sign of digoxin toxicity?
Answer: Visual disturbances.
Rationale: Symptoms like blurred vision or yellow halos indicate digoxin toxicity,
requiring immediate action.
1
NCLEX-Style RN Practice
Questions with Comprehensive
Rationales
Prepared for Nursing Students
July 10, 2025
Contents
1 Introduction 1
2 Practice Questions and Rationales 1
3 Conclusion 9
1
, 1 Introduction
This document provides a focused set of 100 NCLEX-style practice questions with clear,
concise rationales for the HESI Exit Exam 2025, representing a subset of the 750 questions
referenced in the title. Designed for nursing students, the content emphasizes critical
thinking and clinical decision-making, aligned with NCLEX-RN competencies, without
unnecessary complexity.
2 Practice Questions and Rationales
Question 1: What should a nurse monitor in a client receiving furosemide for heart
failure?
Answer: Serum potassium levels.
Rationale: Furosemide, a loop diuretic, can cause hypokalemia, increasing the
risk of arrhythmias in heart failure clients.
Question 2: What is the priority action for a client with an anaphylactic reaction?
Answer: Administer epinephrine.
Rationale: Epinephrine reverses anaphylaxis by constricting blood vessels and
opening airways, addressing life-threatening symptoms.
Question 3: A diabetic client reports shakiness. What is the nurses first action?
Answer: Check blood glucose levels.
Rationale: Shakiness may indicate hypoglycemia, and glucose levels guide appro-
priate treatment.
Question 4: What is the primary cause of hospital-acquired infections?
Answer: Poor hand hygiene.
Rationale: Proper hand hygiene is the most effective way to prevent pathogen
transmission in healthcare settings.
Question 5: What lab value should a nurse monitor for a client on heparin?
Answer: Activated partial thromboplastin time (aPTT).
Rationale: aPTT assesses heparins anticoagulant effect, ensuring therapeutic lev-
els without bleeding risks.
Question 6: What is the priority for a client with a new tracheostomy?
Answer: Ensure airway patency.
Rationale: Maintaining a clear airway prevents respiratory distress in tracheostomy
clients.
Question 7: A client with pneumonia has a fever of 101řF. What should the nurse
do?
Answer: Administer prescribed antipyretics.
Rationale: Antipyretics reduce fever, improving comfort and preventing compli-
cations like seizures.
Question 8: What is a hallmark sign of digoxin toxicity?
Answer: Visual disturbances.
Rationale: Symptoms like blurred vision or yellow halos indicate digoxin toxicity,
requiring immediate action.
1
