Biochem 301 Exam 1 questions with answers

Biochem 301 Exam 1 questions with answers |\ |\ |\ |\ |\ |\




2nd law of thermodynamics - CORRECT ANSWERS ✔✔-nature
|\ |\ |\ |\ |\ |\ |\ |\


tends to become more distorted
|\ |\ |\ |\




-entropy does not decrease in a closed system (entropy will stay
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


the same or increase)
|\ |\ |\




What is the relationship between deltaG and K (equilibrium
|\ |\ |\ |\ |\ |\ |\ |\ |\


constant)? - CORRECT ANSWERS ✔✔As K increases, deltaG|\ |\ |\ |\ |\ |\ |\ |\


decreases.


Relationship between K and Q? - CORRECT ANSWERS ✔✔Q < K -- |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


> reactions proceeds forwards
|\ |\ |\




Q = K --> equilibrium
|\ |\ |\ |\




Q > K --> reactions proceeds backwards
|\ |\ |\ |\ |\ |\




Other amino acids - CORRECT ANSWERS ✔✔-4-hydroxyproline:
|\ |\ |\ |\ |\ |\ |\


found in collagen |\ |\




-ornithine and citrulline are metabolism intermediates
|\ |\ |\ |\ |\




Adding positive charges to amino acid solution will... - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


ANSWERS ✔✔lower the pKa because the amino acid will be more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


likely to give a proton
|\ |\ |\ |\




Adding negative charges to amino acid solution will... - CORRECT
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


ANSWERS ✔✔raise the pKa because the amino acid will be more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\

, likely to keep its proton to avoid resulting in negative-negative
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\


interactions


Amino acids are counted from... - CORRECT ANSWERS ✔✔the N-
|\ |\ |\ |\ |\ |\ |\ |\ |\


terminal end to the C-terminal end
|\ |\ |\ |\ |\




Structure of peptide bond - CORRECT ANSWERS ✔✔-planar
|\ |\ |\ |\ |\ |\ |\




-normally trans |\




Rotation of bonds - CORRECT ANSWERS ✔✔-C-N bond cannot
|\ |\ |\ |\ |\ |\ |\ |\ |\


rotate
-alpha-C's can rotate about their bonds |\ |\ |\ |\ |\




Proline unique conformation - CORRECT ANSWERS ✔✔All amino
|\ |\ |\ |\ |\ |\ |\ |\


acids are in the trans form except proline, which may have some
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


in the cis form due to the steric hindrances caused by the ring
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




Disulfide bonds intracellularly and extracellularly - CORRECT
|\ |\ |\ |\ |\ |\ |\


ANSWERS ✔✔-Disulfide bonds don't typically exist intracellularly
|\ |\ |\ |\ |\ |\




-Exist outside the cell to maintain protein structure in the harsh
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\


external environment to maintain protein structure
|\ |\ |\ |\ |\




-Extracellular environment is oxidizing, resulting in disulfide |\ |\ |\ |\ |\ |\ |\


bonds


Alpha helix structure - CORRECT ANSWERS ✔✔-backbone atoms
|\ |\ |\ |\ |\ |\ |\ |\


follow helical pathway
|\ |\