DISCOVERY LAB EXAM QUESTIONS
AND ANSWERS
what is the purpose in pre-clinical trials - ANSWER-they have in vivo studies on animals
that show the effects of a drug on a target, determine how safe the drug is, and
measure the effectiveness of the drug on a disease
when is a drug application trails posed to the FDA - ANSWER-after preclinical trials
what type of people are used in each stage of clinical trail - ANSWER-stage 1 : young
healthy people, stage 2 : people very sick with said disease, stage 3: people less sick
with said disease, Stage 4: the general public
what is the focus of a stage 2 clinical trail - ANSWER-to look for side effects of the drug
what phase does the drug allow to be used by general public - ANSWER-after phase 3
order phases of clinical trials in terms of riskiness - ANSWER-stage 1, stage 2, stage 3,
stage 4,
what defines a good drug - ANSWER-the drug is easy to take at home, the drug has no
side effects, the drug has no unintended consequences on the body, no withdrawal
symptoms
true of false: Even though screening compounds found in nature is considered a first-
generation approach, this approach is still successfully used to discovery new drugs. -
ANSWER-true
what is a functional group - ANSWER-a functional group that is a part of a compound
can be determined used several different methods in a laboratory, functional groups
give a compound different qualities that may contribute to it being a good or bad drug.
true or false: Changing a functional group on a compound can change the solubility of
the compound. - ANSWER-true
true or false: Clinical trials are required to test the effectiveness of new drugs, medical
tests, and implantable devices like pacemakers. - ANSWER-true
The total amount of time required to develop an FDA-approved drug from the screening
thousands of compounds to availability in the pharmacy is: - ANSWER-15 years
are there more cancer clinical trials or antibiotic resistant clinical trials, why is that? -
ANSWER-There are many more clinical trails on cancer because cancer is seen as the
more pressing matter
AND ANSWERS
what is the purpose in pre-clinical trials - ANSWER-they have in vivo studies on animals
that show the effects of a drug on a target, determine how safe the drug is, and
measure the effectiveness of the drug on a disease
when is a drug application trails posed to the FDA - ANSWER-after preclinical trials
what type of people are used in each stage of clinical trail - ANSWER-stage 1 : young
healthy people, stage 2 : people very sick with said disease, stage 3: people less sick
with said disease, Stage 4: the general public
what is the focus of a stage 2 clinical trail - ANSWER-to look for side effects of the drug
what phase does the drug allow to be used by general public - ANSWER-after phase 3
order phases of clinical trials in terms of riskiness - ANSWER-stage 1, stage 2, stage 3,
stage 4,
what defines a good drug - ANSWER-the drug is easy to take at home, the drug has no
side effects, the drug has no unintended consequences on the body, no withdrawal
symptoms
true of false: Even though screening compounds found in nature is considered a first-
generation approach, this approach is still successfully used to discovery new drugs. -
ANSWER-true
what is a functional group - ANSWER-a functional group that is a part of a compound
can be determined used several different methods in a laboratory, functional groups
give a compound different qualities that may contribute to it being a good or bad drug.
true or false: Changing a functional group on a compound can change the solubility of
the compound. - ANSWER-true
true or false: Clinical trials are required to test the effectiveness of new drugs, medical
tests, and implantable devices like pacemakers. - ANSWER-true
The total amount of time required to develop an FDA-approved drug from the screening
thousands of compounds to availability in the pharmacy is: - ANSWER-15 years
are there more cancer clinical trials or antibiotic resistant clinical trials, why is that? -
ANSWER-There are many more clinical trails on cancer because cancer is seen as the
more pressing matter
