NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
122Week:
- Things22to22know22about22each22of22the22major22antibiotic22drug22classes:2 2
● Examples:
○ Bactericidal22agents:22“BANG22Q22R.I.P”22-22Beta-
lactams,22Aminoglicosides,22Nitroimidazoles22(Metronidazole),22Glycopepti
des22(Vancomycin),22Quinolones,22Rifampicin,22Polymyxins22(Colistin)
○ Bacteriostatic22agents:22“Ms.22Colt”22-
22Macrolides,22Sulfonamides,22Chloramphenicol,22Oxazolidinones,22Lincosamid
es22(Clindamycin),22Tetracyclines
Bactericidal22antibiotics22kill22bacteria22directly,22and22bacteriostatic22a
ntibiotics22stop/weaken22bacteria22from22growing.to22enable22the22immune22sys
tem22to22take22hold22of22infection
-Things22to22know22 about22 each22 of22the22 major22 antibiotic22drug22classes22 (MAKE22FLASHCARDS)
,NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
● Aminoglycosides
● Cephalosporins
● Tetracyclines
● Penicillins
● Sulfonamides
● Fluoroquinolones
,NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
● Macrolides
● Carbapenems
● Lincosamides
● Glycopeptides
o Examples
o Contraindications22and22high-risk22patients
o Know22examples22of22each22of22the22major22antibiotic22drug22classes.
o Monitoring22needs
o Which22ones22require22renal22dosing22adjustments22and22how22much22(i.e.,2225%,2250%,22etc.)
o Patient22education
o Lifespan22considerations22including22pregnancy22o22Indications22for22use
Considerations:2 2
● Renal/hepatic22function:22doses22may22need22to22be22reduced.22Consider22creatinine22clearance.
● Age:22dose22adjustments22may22be22required22for22pediatric22and22geriatric22patient
s-22weight-22based22may22be22appropriate.
● Pregnancy22and22lactation:22Be22aware22of22teratogenic22effects22of22certain2
2classes22of22medications
● Recent22antibiotic22use:22Be22aware22of22possible22drug-resistant22bacteria
● Exposure22history:22travel,22congregate22care22settings,22close22contacts
● Monitoring22needs
○ Next,22consider22the22syndrome,22or22presenting22illness.22--
22What22system22is22impacted?22How22aggressive22is22the22infection?22Consider
22non-bacterial22causes22of22symptoms22(i.e.22viral,22fungal,22or22non-
infections)22Carefully22examine22the22clinical22presentation22of22illness.
● Which22ones22require22renal22dosing22adjustments22and22how22much22(i.e.,2225%,2250%,22etc.
):
VII.22Precautions:22Antibiotics
A. Antibiotics22that22require22NO22renal22dose22adjustment
1. Azithromycin
2. Ceftriaxone
3. Clindamycin
4. Doxycyline
5. Linezolid
6. Moxifloxacin
7. Nafcillin
8. Rifampin
, NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
B. Agents22to22avoid22in22severe22Chronic22Kidney22Disease
1. Penicillin22G22(Myoclonus,22Seizures,22coma22risk)
2. Imipenem22with22cilastin22(Seizure22risk);22Meropenem22safe
3. Tetracycline22(exacerbates22 Uremia);22Doxycycline22 safe
4. Nitrofurantoin22 (peripheral22 neurotoxicity)
5. Aminoglycosides22(or22close22level22monitoring22if22used)
C. Amoxicillin
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
122Week:
- Things22to22know22about22each22of22the22major22antibiotic22drug22classes:2 2
● Examples:
○ Bactericidal22agents:22“BANG22Q22R.I.P”22-22Beta-
lactams,22Aminoglicosides,22Nitroimidazoles22(Metronidazole),22Glycopepti
des22(Vancomycin),22Quinolones,22Rifampicin,22Polymyxins22(Colistin)
○ Bacteriostatic22agents:22“Ms.22Colt”22-
22Macrolides,22Sulfonamides,22Chloramphenicol,22Oxazolidinones,22Lincosamid
es22(Clindamycin),22Tetracyclines
Bactericidal22antibiotics22kill22bacteria22directly,22and22bacteriostatic22a
ntibiotics22stop/weaken22bacteria22from22growing.to22enable22the22immune22sys
tem22to22take22hold22of22infection
-Things22to22know22 about22 each22 of22the22 major22 antibiotic22drug22classes22 (MAKE22FLASHCARDS)
,NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
● Aminoglycosides
● Cephalosporins
● Tetracyclines
● Penicillins
● Sulfonamides
● Fluoroquinolones
,NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
● Macrolides
● Carbapenems
● Lincosamides
● Glycopeptides
o Examples
o Contraindications22and22high-risk22patients
o Know22examples22of22each22of22the22major22antibiotic22drug22classes.
o Monitoring22needs
o Which22ones22require22renal22dosing22adjustments22and22how22much22(i.e.,2225%,2250%,22etc.)
o Patient22education
o Lifespan22considerations22including22pregnancy22o22Indications22for22use
Considerations:2 2
● Renal/hepatic22function:22doses22may22need22to22be22reduced.22Consider22creatinine22clearance.
● Age:22dose22adjustments22may22be22required22for22pediatric22and22geriatric22patient
s-22weight-22based22may22be22appropriate.
● Pregnancy22and22lactation:22Be22aware22of22teratogenic22effects22of22certain2
2classes22of22medications
● Recent22antibiotic22use:22Be22aware22of22possible22drug-resistant22bacteria
● Exposure22history:22travel,22congregate22care22settings,22close22contacts
● Monitoring22needs
○ Next,22consider22the22syndrome,22or22presenting22illness.22--
22What22system22is22impacted?22How22aggressive22is22the22infection?22Consider
22non-bacterial22causes22of22symptoms22(i.e.22viral,22fungal,22or22non-
infections)22Carefully22examine22the22clinical22presentation22of22illness.
● Which22ones22require22renal22dosing22adjustments22and22how22much22(i.e.,2225%,2250%,22etc.
):
VII.22Precautions:22Antibiotics
A. Antibiotics22that22require22NO22renal22dose22adjustment
1. Azithromycin
2. Ceftriaxone
3. Clindamycin
4. Doxycyline
5. Linezolid
6. Moxifloxacin
7. Nafcillin
8. Rifampin
, NR566 / NR 566 Midterm Exam Study Guide (Lates
22 22 22 22 22 22 22 22
t ): Advanced Pharmacology for Care of
2222 22 22 22 22 22 22 22 22
the Family - Chamberlain College
2222 22 22 22
Latest examination Study Guide 2023
22 22 22 22
B. Agents22to22avoid22in22severe22Chronic22Kidney22Disease
1. Penicillin22G22(Myoclonus,22Seizures,22coma22risk)
2. Imipenem22with22cilastin22(Seizure22risk);22Meropenem22safe
3. Tetracycline22(exacerbates22 Uremia);22Doxycycline22 safe
4. Nitrofurantoin22 (peripheral22 neurotoxicity)
5. Aminoglycosides22(or22close22level22monitoring22if22used)
C. Amoxicillin
