PSYCH HESI 2025/2026 Exam Questions
with Detailed Verified Answers (100%
Correct Answers) | Already Graded A+
Imipramine - 🧠ANSWER ✔✔tricyclic antidepressant
Amitriptyline - 🧠ANSWER ✔✔tricyclic antidepressant
Nortriptyline - 🧠ANSWER ✔✔tricyclic antidepressant
Phenelzine - 🧠ANSWER ✔✔MAOI
Isocarboxazid - 🧠ANSWER ✔✔MAOI
Tranyclypromine - 🧠ANSWER ✔✔MAOI
What should the nurse instruct a patient switching antidepressants from
imipramine to phenelzineu to do? - 🧠ANSWER ✔✔Taper down the imipramine
(TCA), then discontinue for two weeks before starting phenelzine (MAOI) to allow
for a washout period
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,If a patient doesn't allow for a washout period between switching antidepressants,
what could they experience? - 🧠ANSWER ✔✔Hypertensive crisis (blurred vision,
dizzy, H/A, SOB) --> discontinuation syndrome
The nurse should instruct the patient taking MAOI's to maintain what kind of diet?
WHY? - 🧠ANSWER ✔✔Tyramine restricted diet to reduce risk of hypertensive
crisis
What two antidepressants cannot be taken at the same time due to risk of a
hypertensive crisis? - 🧠ANSWER ✔✔TCA's and MAOI's
Clozapine - 🧠ANSWER ✔✔atypical antipsychotic used for schizophrenia
Clozapine S/E - 🧠ANSWER ✔✔agranulocytosis, tachycardia and seizures,
myocarditis, increased ROI (fever, sore throat, flu like symptoms), weight gain,
hyper salivation and drooling
What should a nurse assess for in a patient taking Clozapine? - 🧠ANSWER
✔✔agranulocytosis- which increases risk of infection. Patient should be monitored
for S/S of infection (fever, flu like)
SSRI and MAOI should not be combined to to risk of - 🧠ANSWER ✔✔serotonin
syndrome
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STATEMENT. ALL RIGHTS RESERVED
2
, wait 14 days before starting a new antidepressant
Neuroleptic Malignant Syndrome - 🧠ANSWER ✔✔Adverse reaction to
antipsychotics with severe muscle rigidty, FEVER, AMS, sweating, hypertension,
tachy
NMS is most often seen with which antipsychotics - 🧠ANSWER ✔✔Atypical
Antipsychotics
Haldol, fluphenazine, clozapine, risperidone, olanzapine
Bentropine (Cogentin) - 🧠ANSWER ✔✔anticholinergic medication used to treat
EPE (pseudoparkinsonism, dystonia)
Pseudoparkinsonism - 🧠ANSWER ✔✔mask like face, tremor, shuffling gait,
drooling, rigidity, bradykinesia
Dystonia - 🧠ANSWER ✔✔abnormal muscle movements of the face, neck, and
trunk that caused by sustained muscle contractions & impairs voluntary muscle
movement
Tangentiality - 🧠ANSWER ✔✔Abrupt changing of focus to a loosely associated
topic seen in schizophrenia
wavy flexibility - 🧠ANSWER ✔✔-motor disturbance seen in schizophrenia
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
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with Detailed Verified Answers (100%
Correct Answers) | Already Graded A+
Imipramine - 🧠ANSWER ✔✔tricyclic antidepressant
Amitriptyline - 🧠ANSWER ✔✔tricyclic antidepressant
Nortriptyline - 🧠ANSWER ✔✔tricyclic antidepressant
Phenelzine - 🧠ANSWER ✔✔MAOI
Isocarboxazid - 🧠ANSWER ✔✔MAOI
Tranyclypromine - 🧠ANSWER ✔✔MAOI
What should the nurse instruct a patient switching antidepressants from
imipramine to phenelzineu to do? - 🧠ANSWER ✔✔Taper down the imipramine
(TCA), then discontinue for two weeks before starting phenelzine (MAOI) to allow
for a washout period
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
1
,If a patient doesn't allow for a washout period between switching antidepressants,
what could they experience? - 🧠ANSWER ✔✔Hypertensive crisis (blurred vision,
dizzy, H/A, SOB) --> discontinuation syndrome
The nurse should instruct the patient taking MAOI's to maintain what kind of diet?
WHY? - 🧠ANSWER ✔✔Tyramine restricted diet to reduce risk of hypertensive
crisis
What two antidepressants cannot be taken at the same time due to risk of a
hypertensive crisis? - 🧠ANSWER ✔✔TCA's and MAOI's
Clozapine - 🧠ANSWER ✔✔atypical antipsychotic used for schizophrenia
Clozapine S/E - 🧠ANSWER ✔✔agranulocytosis, tachycardia and seizures,
myocarditis, increased ROI (fever, sore throat, flu like symptoms), weight gain,
hyper salivation and drooling
What should a nurse assess for in a patient taking Clozapine? - 🧠ANSWER
✔✔agranulocytosis- which increases risk of infection. Patient should be monitored
for S/S of infection (fever, flu like)
SSRI and MAOI should not be combined to to risk of - 🧠ANSWER ✔✔serotonin
syndrome
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
2
, wait 14 days before starting a new antidepressant
Neuroleptic Malignant Syndrome - 🧠ANSWER ✔✔Adverse reaction to
antipsychotics with severe muscle rigidty, FEVER, AMS, sweating, hypertension,
tachy
NMS is most often seen with which antipsychotics - 🧠ANSWER ✔✔Atypical
Antipsychotics
Haldol, fluphenazine, clozapine, risperidone, olanzapine
Bentropine (Cogentin) - 🧠ANSWER ✔✔anticholinergic medication used to treat
EPE (pseudoparkinsonism, dystonia)
Pseudoparkinsonism - 🧠ANSWER ✔✔mask like face, tremor, shuffling gait,
drooling, rigidity, bradykinesia
Dystonia - 🧠ANSWER ✔✔abnormal muscle movements of the face, neck, and
trunk that caused by sustained muscle contractions & impairs voluntary muscle
movement
Tangentiality - 🧠ANSWER ✔✔Abrupt changing of focus to a loosely associated
topic seen in schizophrenia
wavy flexibility - 🧠ANSWER ✔✔-motor disturbance seen in schizophrenia
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3
