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Chapter 01: Cellular Biology
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Test Bank
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, Test Bank Understanding Pathophysiology 7th Edition
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Huether & McCance: Understanding Pathophysiology, 7th Edition
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MULTIPLE CHOICES N
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA
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with histones. Which of the following would also be observed by the student?
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a. A single circular chromosome
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b. A nucleus N
c. Free-floating nuclear material N N
d. No organelles N
ANS: B N
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its
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nucleus; thus, the nucleus should be observed. A single circular chromosome called a prok
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aryote contains free-floating nuclear material but has no organelles.
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REF: p. 2 N N
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
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describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption N
b. Communication
c. Secretion
d. Respiration
ANS: D N
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, Test Bank Understanding Pathophysiology 7th Edition
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The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
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involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and s
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ecretion allows for the synthesizing of new substances.
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REF: p. 2 N N
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of
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the genetic information be contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm N
ANS: C N
The region of the cell that contains genetic material, including a large amount of ribonucleic
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acid, most of the DNA, and DNA-
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binding proteins, is the nucleolus, which is located withinthe cell’s nucleus. Mitochondria is
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N associated with cellular respiration, while ribosomes are involved with protein manufacturi
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ng. Cytoplasm is a fluid filling that is a component of the cell.
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REF: p. 2 N N
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the
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layer itself? N
a. Peripheral membrane proteins N N
b. Integral membrane proteins N N
c. Glycoproteins
d. Cell adhesion molecules N N
ANS: B N
Proteins directly attached to the membrane bilayer can be removed by the action of integral
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membrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the surf
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ace while cell adhesion molecules are on the outside of the membrane. Glycoprotein marks
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cells and does not float.
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REF: p. 7 N N
5. Which of the following can bind to plasma membrane receptors?
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, Test Bank Understanding Pathophysiology 7th Edition
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a. Oxygen
b. Ribosomes
c. Amphipathic lipids N
d. Ligands
ANS: D N
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
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REF: p. 9 N N
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
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pU
extracellular matrix would suNpoRrtSthIeNdG
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gnBo.
siC
s ofM
metastatic cancer?
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a. Decreased fibronectin N
b. Increased collagen N
c. Decreased elastin N
d. Increased glycoproteins N
ANS: A N
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing
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them to travel or metastasize.
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REF: p. 10 N N
7. Which form of cell communication is used to relate to other cells in direct physical contact?
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a. Cell junction N
b. Gap junction N
c. Desmosome
d. Tight junction N
ANS: A N
Cell junctions hold cells together and permit molecules to pass from cell to cell.
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Gap junctions allow for cellular communication between cells. Neither desmosomes nor tight
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junctions are associated with cellular communication.
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REF: p. 11 N N
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