Basic and Clinical Pharmacology, 15th Edition TEST BANK by Bertram G. Katzung, Verified//Fully chaptered

Basic and Clinical Pharmacology 15th Edition
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Katzung Trevor Test Bank Update 2023/2024
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TEST BANK n

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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a patient who is having a
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computed tomography (CT) scan. The nurse working on the oncology unit
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administers chemotherapy to patients who have cancer. At the Public Health
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Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
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a 14-month-old child as a routine immunization. Which branch of
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pharmacology best describes the actions of all three nurses?
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A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

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Pharmacology is the study of the biologic effects of chemicals. Nurses are
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involved with clinical pharmacology or pharmacotherapeutics, which is a
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branch of pharmacology that deals with the uses of drugs to treat, prevent,
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and diagnose disease. The radiology nurse is administering a drug to help
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diagnose a disease. The oncology nurse is administering a drug to help treat a
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disease. Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and n n n n n n n n


pharmacokinetics is how the body acts on the body.
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2. When involved in phase III drug evaluation studies, what responsibilities
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would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C

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Phase III studies involve use of a drug in a vast clinical population in which
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patients are asked to record any symptoms they experience while taking the
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drugs. Nurses may be responsible for helping collect and analyze the
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information to be shared with the Food and Drug Administration (FDA) but
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would not conduct research independently because nurses do not prescribe
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medications. Use of animals in drug testing is done in the preclinical trials.
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Select patients who are involved in phase II studies to participate in studies
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where the participants have the disease the drug is intended to treat. These
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patients are monitored closely for drug action and adverse effects. Phase I
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studies involve healthy human volunteers who are usually paid for their
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participation. Nurses may observe for adverse effects and toxicity.
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3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
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The nurse is aware this drug has a high abuse potential. Under what
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category would morphine be classified?
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A) Schedule I n




B) Schedule II n




C) Schedule III n




D) Schedule IV n




Ans: B

Feedback:

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs have
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low abuse potential and limited dependence liability.
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4. What concept is considered when generic drugs are substituted for brand
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name drugs?
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A) Bioavailability

B) Critical concentration n




C) Distribution

D) Half-life

Ans: A

Feedback:

Bioavailability is the portion of a dose of a drug that reaches the systemic
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circulation and is available to act on body cells. Binders used in a generic
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drug may not be the same as those used in the brand name drug. Therefore,
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the way the body breaks down and uses the drug may differ, which may
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eliminate a generic drug substitution. Critical concentration is the amount of
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a drug that is needed to cause a therapeutic effect and should not differ
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between generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the bodys
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tissues and is the same in generic and brand name drugs. A drugs half-life is
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the time it takes for the amount of drug to decrease to half the peak level,
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which should not change when substituting a generic medication.
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5. A nurse is assessing the patients home medication use. After listening to the
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patient list current medications, the nurse asks what priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D

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