NUR 641E Midterm /NUR 641E
Midterm Study Guide with
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Terms in this set (106)
, An inactive drug dosage form that is
converted to an active metabolite
by various biochemical reactions
Prodrug
once it is inside the body.
-Cytochrome P450
-Ex. Aspirin, psilocybin, heroin
the rate at and the extent to which a
nutrient is absorbed and used
-Affected by route of administration
and drug dosage
Bioavailability -Drug clearance (rate drug leaves
circulation)
-Steady state concentration
-Affected by chemical stability,
solubility, and first pass
stable level of drug in the body,
occurs in 5 half lives of the drug
Steady state (of
-rate of drug being added to system
a drug)
is equal to amount being eliminated
from system
The process by which drugs are
Pharmacokinetic absorbed, distributed within the
s body, metabolized, and excreted.
-what the body does to the drug
, the fact that a medication in the GI
First pass tract passes through the liver before
entering other organs
bioequivalence does/does not
does not
affect bioavailability
relative therapeutic effectiveness of
Bioequivalence
chemically equivalent drugs.
-chemical instability
Bioavailability (is
-solubility
affected by)
-first pass metabolism
Midterm Study Guide with
Complete Solution 2025
Save
Practice questions for this set
Learn
Studied 7 terms
Nice work, you're crushing it
Continue studying in Learn
Terms in this set (106)
, An inactive drug dosage form that is
converted to an active metabolite
by various biochemical reactions
Prodrug
once it is inside the body.
-Cytochrome P450
-Ex. Aspirin, psilocybin, heroin
the rate at and the extent to which a
nutrient is absorbed and used
-Affected by route of administration
and drug dosage
Bioavailability -Drug clearance (rate drug leaves
circulation)
-Steady state concentration
-Affected by chemical stability,
solubility, and first pass
stable level of drug in the body,
occurs in 5 half lives of the drug
Steady state (of
-rate of drug being added to system
a drug)
is equal to amount being eliminated
from system
The process by which drugs are
Pharmacokinetic absorbed, distributed within the
s body, metabolized, and excreted.
-what the body does to the drug
, the fact that a medication in the GI
First pass tract passes through the liver before
entering other organs
bioequivalence does/does not
does not
affect bioavailability
relative therapeutic effectiveness of
Bioequivalence
chemically equivalent drugs.
-chemical instability
Bioavailability (is
-solubility
affected by)
-first pass metabolism
