@ko @ko
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action
2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration @koof @kooxytocin @kohas @kobeen @koproposed @koas @koa @kotreatment
@kofor @koautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: @koc
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
6. Which @kofactor @kodoes @konot @koaffect @kothe @kopharmacokinetics @koof @koa @kodrug?
a. Route @koof @koadministration
b. Lipid @kosolubility
c. Depot @kobinding
d. Drug @koaction
Answer: @kod
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
7. First-pass @kometabolism @kooccurs @kowhen @kodrugs @koare @kotaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: @koa
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
8. The @koarea @kopostrema @kois @koone @koarea @koin @kothe @kobrain @kowhere @kothe is @konot @kocomplete.
a. cerebrospinal @kofluid
b. blood–brain @kobarrier
c. choroid @koplexus
d. phospholipid @komembrane
Answer: @kob
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
9. First-pass @kometabolism @kooccurs @kowith @koorally @koadministered @kodrugs @kobecause
a. their @koabsorption @kois @koslowed @koby @kofood.
b. drugs @koabsorbed @kointo @kothe @kobloodstream @kofrom @kothe @kostomach @kogo @koto @kothe
@koliver @koon @kothe @koway @koto @kogeneral @kocirculation.
c. drugs @komust @kofirst @kosurvive @kothe @koacidic @koenvironment @koof @kothe @kostomach.
d. salivary @koenzymes @koin @kothe @komouth @kobegin @kothe @koprocess @koof @kometabolism.
Answer: @kob
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
10. Toxic @kosubstances @koin @kothe @koblood @kotrigger @koa @kovomiting @koresponse @koby @koactivating
@kothe
a. blood–brain @kobarrier.
b. choroid @koplexus.
c. area @kopostrema.
d. median @koeminence.
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, Answer: @koc
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
11. Drugs @koadministered @ko_ have @kothe @komost @korapid @koonset @koof @koaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: @kod
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
12. Ionization @koof @koa @kodrug @kodepends @koon @kothe of @kothe @kosolution @koand @kothe of
@kothe @kodrug.
a. pH; @kopKa
b. pKa; @kopH
c. concentration; @kolipid @kosolubility
d. pH; @koconcentration
Answer: @koa
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
13. The @koabsorption @koof @koa @kodrug @kodepends @koon @koall @koof @kothe @kofollowing @koexcept
a. lipid @kosolubility.
b. ionization.
c. body @kotemperature.
d. the @koconcentration @koof @kothe @kodrug.
Answer: @koc
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
14. Drugs @kothat @koare should @kobe @koavoided @koby @kowomen @koof @kochildbearing @koage.
a. teratogenic
b. able @koto @kocross @kothe @koplacental @kobarrier
c. psychoactive
d. highly @kolipid-soluble
Answer: @koa
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
15. Agents @kothat @koinduce @kodevelopmental @koabnormalities @koin @koa @kofetus @koare @koknown @koas
a. psychoactive @kodrugs.
b. illicit @kodrugs.
c. teratogens.
d. placental @kodrugs.
Answer: @koc
Textbook @koReference: @koPharmacokinetic @koFactors @koDetermining @koDrug @koAction
16. Depot @kobinding @kois @kosaid @koto @kooccur @kowhen @kodrugs
a. bind @koto @kotheir @kotarget @kosites.
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