A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
How do antigout medications work? - ANSWER by inhibiting the infiltration and phagocytosis of
leukocytes, thus decreasing the breakdown of uric acid to urate crystals.
Deposition of urate crystals causes - ANSWER pain and inflammation
What is Colchicine - ANSWER anti-gout medication
how does Colchicine work? - ANSWER Works by inhibiting inflammation, reducing pain and swelling
common side effects of Colchicine - ANSWER GI problems (diarrhea) use with caution in elderly
Also can cause blood dyscrasias & abdominal pain
patient education with Colchicine - ANSWER Can be given with food & milk to decrease GI issues
Avoid beer, ale, & wine: may cause gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
Low dose of Colchicine - ANSWER Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8
milligrams total
High dose of Colchicine - ANSWER high dose colchicine is 1.2mg followed by 0.6mg every four to six
hours; or 4.8mg total.
Difference between high dose and low dose Colchicine - ANSWER The difference between the two is low
dose is as effective as high dose with a lower side effect profile.
,A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
Lab values to monitor with Colchicine - ANSWER Check renal function test, BUN, Creatine
Patient education with Colchicine - ANSWER Almost always causes some degree of diarrhea, make sure
patients are aware of this side effect
Patient education with Febuxostat (Uloric) - ANSWER Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid deposits. - ANSWER Avoid beer, ale, & wine
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
WHO 3 step ladder for pain medication - ANSWER
What is not a first line for pain medication? - ANSWER Narcotics
Recommendations for pain treatment - ANSWER You want to start with NSAIDs first and then work your
way up from there.
types of Corticosteroid treatment - ANSWER Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work? - ANSWER Suppress the inflammatory & immune systems by inhibiting
the synthesis of chemical mediators.
what are the chemical mediators that Corticosteroids work on? - ANSWER Prostaglandins, leukotrienes,
& histamines
Corticosteroids and inflammation - ANSWER Decreases inflammation which decreases swelling, warmth,
redness, & pain.
, A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
Uses for corticosteroid treatment - ANSWER Addison's disease, hormone replacement, cancer therapy
SLE, arthritis, IBD, & to suppress graft rejection
contraindications for corticosteroid treatment - ANSWER Systemic fungal infections & with live vaccine
Use corticosteroids cautiously with: - ANSWER Pregnancy, kids, HTN, heart failure, renal impairment, &
with infections resistant to treatment
Patient education with corticosteroids - ANSWER Don't discontinue abruptly, doses may need increased
during stress, symptoms of Cushing's and GI bleeding
Problem with taking Corticosteroids for greater than 6 months - ANSWER The main thing you want to
worry about is osteoporosis it can also worsen diabetic control and patients should report any tarry
black stools or abdominal pain.
Other common side effects with Corticosteroids - ANSWER Peptic ulcers, GI bleeding, edema,
hyperglycemia, delayed wound healing, fluid & electrolyte imbalances
Why is it important to tapper the corticosteroid? - ANSWER Tapering must be done carefully to avoid
both recurrent activity of the underlying disease process and possible cortisol deficiency resulting from
the hypothalamic-pituitary-adrenal axis or HPA suppression during the period of steroid therapy
Black box warning - ANSWER Increased risk of serious cardiovascular thrombotic events, myocardial-
infarction and stroke which can be fatal.
What increases risk of black box warning occurring with NSAIDs. - ANSWER Risk increases with duration
of use.
Patients with cardiovascular disease or with risk factors for cardiovascular disease may be a greater risk.
with correct complete solutions
A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
How do antigout medications work? - ANSWER by inhibiting the infiltration and phagocytosis of
leukocytes, thus decreasing the breakdown of uric acid to urate crystals.
Deposition of urate crystals causes - ANSWER pain and inflammation
What is Colchicine - ANSWER anti-gout medication
how does Colchicine work? - ANSWER Works by inhibiting inflammation, reducing pain and swelling
common side effects of Colchicine - ANSWER GI problems (diarrhea) use with caution in elderly
Also can cause blood dyscrasias & abdominal pain
patient education with Colchicine - ANSWER Can be given with food & milk to decrease GI issues
Avoid beer, ale, & wine: may cause gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
Low dose of Colchicine - ANSWER Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8
milligrams total
High dose of Colchicine - ANSWER high dose colchicine is 1.2mg followed by 0.6mg every four to six
hours; or 4.8mg total.
Difference between high dose and low dose Colchicine - ANSWER The difference between the two is low
dose is as effective as high dose with a lower side effect profile.
,A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
Lab values to monitor with Colchicine - ANSWER Check renal function test, BUN, Creatine
Patient education with Colchicine - ANSWER Almost always causes some degree of diarrhea, make sure
patients are aware of this side effect
Patient education with Febuxostat (Uloric) - ANSWER Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid deposits. - ANSWER Avoid beer, ale, & wine
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
WHO 3 step ladder for pain medication - ANSWER
What is not a first line for pain medication? - ANSWER Narcotics
Recommendations for pain treatment - ANSWER You want to start with NSAIDs first and then work your
way up from there.
types of Corticosteroid treatment - ANSWER Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work? - ANSWER Suppress the inflammatory & immune systems by inhibiting
the synthesis of chemical mediators.
what are the chemical mediators that Corticosteroids work on? - ANSWER Prostaglandins, leukotrienes,
& histamines
Corticosteroids and inflammation - ANSWER Decreases inflammation which decreases swelling, warmth,
redness, & pain.
, A.T Pharm Exam 3 Maryville NURS 615
with correct complete solutions
Uses for corticosteroid treatment - ANSWER Addison's disease, hormone replacement, cancer therapy
SLE, arthritis, IBD, & to suppress graft rejection
contraindications for corticosteroid treatment - ANSWER Systemic fungal infections & with live vaccine
Use corticosteroids cautiously with: - ANSWER Pregnancy, kids, HTN, heart failure, renal impairment, &
with infections resistant to treatment
Patient education with corticosteroids - ANSWER Don't discontinue abruptly, doses may need increased
during stress, symptoms of Cushing's and GI bleeding
Problem with taking Corticosteroids for greater than 6 months - ANSWER The main thing you want to
worry about is osteoporosis it can also worsen diabetic control and patients should report any tarry
black stools or abdominal pain.
Other common side effects with Corticosteroids - ANSWER Peptic ulcers, GI bleeding, edema,
hyperglycemia, delayed wound healing, fluid & electrolyte imbalances
Why is it important to tapper the corticosteroid? - ANSWER Tapering must be done carefully to avoid
both recurrent activity of the underlying disease process and possible cortisol deficiency resulting from
the hypothalamic-pituitary-adrenal axis or HPA suppression during the period of steroid therapy
Black box warning - ANSWER Increased risk of serious cardiovascular thrombotic events, myocardial-
infarction and stroke which can be fatal.
What increases risk of black box warning occurring with NSAIDs. - ANSWER Risk increases with duration
of use.
Patients with cardiovascular disease or with risk factors for cardiovascular disease may be a greater risk.
