Immunology HMX
dactylitis - ANSWER: Inflammation of an entire digit (a finger or a toe), also referred to as 'sausage digit'.
Enthesitis - ANSWER: Inflammation of the site where a tendon or ligament inserts into a bone.
Intertriginous - ANSWER: Referring to areas where skin rubs together, such as under the armpits and in the
groin.
Lymphocytes - ANSWER: Small leukocytes that are central players in the adaptive immune system. include T
cells and B cells.
Plasmacytoid dendritic cell (pDC) - ANSWER: A type of dendritic cell that produces large amounts of type I
interferon.
TNFα - ANSWER: A pro-inflammatory cytokine, often released by macrophages and dendritic cells early in
acute inflammation.
Type I interferon (type I IFN) - ANSWER: A class of pro-inflammatory cytokines. group of cytokines that initiate
signaling that activates the antiviral state. can be produced by most cells in the body, but pDCs are very
efficient at producing these cytokines.
innate immune system - ANSWER: Exists before exposure to pathogens
Capable of very rapid response
Required to activate slower adaptive immune system
Inflammation - ANSWER: delivery of cells, proteins and fluid into infected or injured tissue, defense against
microbes or repair of tissue
Leukocytes (WBC) - ANSWER: Neutrophils (polymorphonuclear leukocytes), Monocytes, Lymphocytes,
Eosinophils, Basophils
dactylitis - ANSWER: Inflammation of an entire digit (a finger or a toe), also referred to as 'sausage digit'.
Enthesitis - ANSWER: Inflammation of the site where a tendon or ligament inserts into a bone.
Intertriginous - ANSWER: Referring to areas where skin rubs together, such as under the armpits and in the
groin.
Lymphocytes - ANSWER: Small leukocytes that are central players in the adaptive immune system. include T
cells and B cells.
Plasmacytoid dendritic cell (pDC) - ANSWER: A type of dendritic cell that produces large amounts of type I
interferon.
TNFα - ANSWER: A pro-inflammatory cytokine, often released by macrophages and dendritic cells early in
acute inflammation.
Type I interferon (type I IFN) - ANSWER: A class of pro-inflammatory cytokines. group of cytokines that initiate
signaling that activates the antiviral state. can be produced by most cells in the body, but pDCs are very
efficient at producing these cytokines.
innate immune system - ANSWER: Exists before exposure to pathogens
Capable of very rapid response
Required to activate slower adaptive immune system
Inflammation - ANSWER: delivery of cells, proteins and fluid into infected or injured tissue, defense against
microbes or repair of tissue
Leukocytes (WBC) - ANSWER: Neutrophils (polymorphonuclear leukocytes), Monocytes, Lymphocytes,
Eosinophils, Basophils
