,TABLE OF CONTENTS
UNIT I Introduction to Pharmacology
1 Basic Principles of Pharmacology
2 Drug Actions Across the Life Span
3 The Nursing Process and Pharmacology
4 Patient Education to Promote Health
UNIT II Medication Administration
5 Principles of Medication Administration and Medication Safety
6 Percutaneous Administration
7 Enteral Administration
8 Parenteral Administration: Safe Preparation
9 Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
10 Parenteral Administration: Intravenous
UNIT III Drugs Affecting Neurologic Disorders
11 Drugs Affecting the Central and Peripheral Nervous System
12 Drugs Used to Treat Neurodegenerative Disorders
13 Drugs Used to Treat Seizure Disorders
14 Drugs Used to Treat Headaches
15 Drugs Used to Treat Pain: Focus on Opioids
UNIT IV Drugs Affecting Psychiatric Disorders
16 Drugs Used to Treat Attention Deficit Hyperactivity Disorder
17 Drugs Used to Treat Substance Use Disorders
18 Drugs Used to Treat Schizophrenia
19 Drugs Used to Treat Depressive and Bipolar Disorders
20 Drugs Used to Treat Anxiety Disorders
21 Drugs Used to Treat Sleep Disorders
UNIT V Drugs Affecting Cardiovascular Disorders
22 Drugs Used to Treat Dyslipidemias
23 Drugs Used to Treat Hypertension
24 Drugs Used to Treat Arrhythmias
25 Drugs Used to Treat Angina Pectoris
26 Drugs Used to Treat Peripheral Vascular Disease
27 Drugs Used to Treat Thromboembolic Disorders
28 Drugs Used to Treat Heart Failure
UNIT VI Drugs Affecting the Respiratory System
29 Drugs Used to Treat Upper Respiratory Disease
30 Drugs Used to Treat Lower Respiratory Disease
UNIT VII Drugs Affecting the Digestive System
31 Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
32 Drugs Used to Treat Nausea and Vomiting
33 Drugs Used to Treat Constipation and Diarrhea
UNIT VIII Drugs Affecting the Endocrine System
34 Drugs Used to Treat Diabetes Mellitus
35 Drugs Used to Treat Thyroid Disease
UNIT IX Drugs Affecting the Reproductive System
36 Drugs Used in Obstetrics
37 Drugs Used in Men’s and Women’s Health
UNIT X Drugs Affecting Other Body Systems
38 Drugs Used to Treat Urinary System Disorders
39 Drugs Used to Treat Glaucoma and Other Eye Disorders
40 Drugs Used to Treat Cancer
41 Drugs Used to Treat Musculoskeletal Disorders
42 Drugs Used to Treat Immune and Inflammatory Disorders
,UNIT XI Drugs Used to Treat Infections
43 Drugs Used to Treat Bacterial Infections
44 Drugs Used to Treat Viral Infections
45 Drugs Used to Treat Fungal Infections
Chapter 01: Basic Principles of Pharmacology Willihnga nz: Clayton’s Basic
Pharmacology for Nurses, 20th Edition
MULTIPLE CHOICE
1. Which priority action should be implemented when hives are assessed on a patient started o
n a new medication?
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a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify the physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticari
a, w h i c h are easily identified. An idiosyncratic reaction occurs when something unusual or
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abnormal happens when a drug is first administered. A teratogenic reaction refers to the oc
currence of birth defects related to administration of the drug. Tolerance refers to the body‘s
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requirement for increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: p. 17 OBJ: 4
, NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
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2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes a fter
administration, the nurse finds the patient agitated and stating that ―everyone is out to get
me.‖ Which term is used for this unusual reaction?
a. Desired action
b. Adverse effect
c. Idiosyncratic reaction
d. Allergic reaction
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
administered. Patients typically exhibit an overresponsiveness to a medication related
to diminished metabolism. These reactions are believed to be related to genetic enzy
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me deficiencies. Desired actions are expected responses to a medication. Adverse effect
s are reactions that occur in another system of the body; they are usually predictable.
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Allergic reactions appear after repeated medication dosages.
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DIF: Cognitive Level: Knowledge REF: p. 18
OBJ: 4 NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Evaluation
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
3. Which is the best description of when drug interactions occur?
a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
c. On the alteration of the effect of one drug by another drug
d. On increase of drug excretion
ANS: C
Drug interactions may be characterized by an increase or decrease in the effectiveness of o
ne or both of the drugs. Toxicity of one drug may or may not affect the metabolism of an
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other one. Drug interactions may result from either increased or decreased pharmacodyna
mics.
Drug interactions mayresult from either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: p. 18
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Int
lw
egrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which term describes when two drugs compete for the same receptor site, resulting
in increased activity of the first drug?
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a. Desired action wl
b. Synergistic effect
c. Carcinogenicity
d. Displacement
ANS: D
UNIT I Introduction to Pharmacology
1 Basic Principles of Pharmacology
2 Drug Actions Across the Life Span
3 The Nursing Process and Pharmacology
4 Patient Education to Promote Health
UNIT II Medication Administration
5 Principles of Medication Administration and Medication Safety
6 Percutaneous Administration
7 Enteral Administration
8 Parenteral Administration: Safe Preparation
9 Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
10 Parenteral Administration: Intravenous
UNIT III Drugs Affecting Neurologic Disorders
11 Drugs Affecting the Central and Peripheral Nervous System
12 Drugs Used to Treat Neurodegenerative Disorders
13 Drugs Used to Treat Seizure Disorders
14 Drugs Used to Treat Headaches
15 Drugs Used to Treat Pain: Focus on Opioids
UNIT IV Drugs Affecting Psychiatric Disorders
16 Drugs Used to Treat Attention Deficit Hyperactivity Disorder
17 Drugs Used to Treat Substance Use Disorders
18 Drugs Used to Treat Schizophrenia
19 Drugs Used to Treat Depressive and Bipolar Disorders
20 Drugs Used to Treat Anxiety Disorders
21 Drugs Used to Treat Sleep Disorders
UNIT V Drugs Affecting Cardiovascular Disorders
22 Drugs Used to Treat Dyslipidemias
23 Drugs Used to Treat Hypertension
24 Drugs Used to Treat Arrhythmias
25 Drugs Used to Treat Angina Pectoris
26 Drugs Used to Treat Peripheral Vascular Disease
27 Drugs Used to Treat Thromboembolic Disorders
28 Drugs Used to Treat Heart Failure
UNIT VI Drugs Affecting the Respiratory System
29 Drugs Used to Treat Upper Respiratory Disease
30 Drugs Used to Treat Lower Respiratory Disease
UNIT VII Drugs Affecting the Digestive System
31 Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
32 Drugs Used to Treat Nausea and Vomiting
33 Drugs Used to Treat Constipation and Diarrhea
UNIT VIII Drugs Affecting the Endocrine System
34 Drugs Used to Treat Diabetes Mellitus
35 Drugs Used to Treat Thyroid Disease
UNIT IX Drugs Affecting the Reproductive System
36 Drugs Used in Obstetrics
37 Drugs Used in Men’s and Women’s Health
UNIT X Drugs Affecting Other Body Systems
38 Drugs Used to Treat Urinary System Disorders
39 Drugs Used to Treat Glaucoma and Other Eye Disorders
40 Drugs Used to Treat Cancer
41 Drugs Used to Treat Musculoskeletal Disorders
42 Drugs Used to Treat Immune and Inflammatory Disorders
,UNIT XI Drugs Used to Treat Infections
43 Drugs Used to Treat Bacterial Infections
44 Drugs Used to Treat Viral Infections
45 Drugs Used to Treat Fungal Infections
Chapter 01: Basic Principles of Pharmacology Willihnga nz: Clayton’s Basic
Pharmacology for Nurses, 20th Edition
MULTIPLE CHOICE
1. Which priority action should be implemented when hives are assessed on a patient started o
n a new medication?
lw
a. Notify physician of allergic reaction.
b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
d. Notify the physician of potential tolerance.
ANS: A
An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticari
a, w h i c h are easily identified. An idiosyncratic reaction occurs when something unusual or
l w
abnormal happens when a drug is first administered. A teratogenic reaction refers to the oc
currence of birth defects related to administration of the drug. Tolerance refers to the body‘s
lw
requirement for increasing dosages to achieve the same effects that a lower dose once did.
DIF: Cognitive Level: Application REF: p. 17 OBJ: 4
, NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
wl
2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes a fter
administration, the nurse finds the patient agitated and stating that ―everyone is out to get
me.‖ Which term is used for this unusual reaction?
a. Desired action
b. Adverse effect
c. Idiosyncratic reaction
d. Allergic reaction
ANS: C
Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
administered. Patients typically exhibit an overresponsiveness to a medication related
to diminished metabolism. These reactions are believed to be related to genetic enzy
lw
me deficiencies. Desired actions are expected responses to a medication. Adverse effect
s are reactions that occur in another system of the body; they are usually predictable.
lw
Allergic reactions appear after repeated medication dosages.
lw
DIF: Cognitive Level: Knowledge REF: p. 18
OBJ: 4 NAT: NCLEX Client Needs Category: Physiological Int
lw
egrity
TOP: Nursing Process Step: Evaluation
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
3. Which is the best description of when drug interactions occur?
a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
c. On the alteration of the effect of one drug by another drug
d. On increase of drug excretion
ANS: C
Drug interactions may be characterized by an increase or decrease in the effectiveness of o
ne or both of the drugs. Toxicity of one drug may or may not affect the metabolism of an
lw
other one. Drug interactions may result from either increased or decreased pharmacodyna
mics.
Drug interactions mayresult from either increased or decreased excretion.
DIF: Cognitive Level: Comprehension REF: p. 18
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Int
lw
egrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which term describes when two drugs compete for the same receptor site, resulting
in increased activity of the first drug?
lw
a. Desired action wl
b. Synergistic effect
c. Carcinogenicity
d. Displacement
ANS: D
