NR 507 MIDTERM EXAM AND FINAL EXAM 2025 | ALL QUESTIONS AND CORRECT ANSWERS (DETAILED
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1. Who is at risk for hemolytic anemia? - mismatched blood types (cytotoxic Type 2 - de-
stroys RBCs)
- autoimmune hemolytic anemia d/t autoanti-
bodies against erythrocytes (seen as an antigen
and is attacked)
- allergic reaction to a drug that causes drug-in-
duced hemolytic anemia
2. Neutrophils What WBC is the first to appear in any immune
response?
3. Sensitization Occurs after an initial encounter with an allergen
4. IgE antibodies What antibodies are associated with Type 1 Hy-
persensitivity Reactions?
5. Anaphylaxis A Type 1 Hypersensitivity Reaction mediated by
IgE and mast cells where those who have been
exposed are highly sensitized
6. Inflammatory mediators Produce vasodilation, bronchial smooth muscle
contraction, and mucus production in a hyper-
sensitivity reaction
7. Urticaria An example of a Type 1 Hypersensitivity Reaction
where hives and eosinophilia are noted in the
reaction
8. Type 1 This type of hypersensitivity reaction is also con-
sidered an allergic reaction
9. Type 2
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This type of hypersensitivity reaction is tissue spe-
cific - aka it occurs because of happens that cause
a response mediated by IgG and IgM antibodies
10. IgG and IgM What antibodies are present in a Type 2 Hyper-
sensitivity Reaction?
11. Type 2 Hypersensitivity Reaction In this reaction, antibodies are specifically direct-
ed to the antigen located on the cell membrane,
and thus is organ specific.
12. Hapten A small molecule that can cause an immune re-
sponse when it attaches to a protein
13. Macrophages What are the primary effector cells in Type 2 Hy-
persensitivity Reactions?
14. What is the first action in a Type 2 Hy- Cell to be destroyed by the antibody
persensitivity Reaction?
15. How is cell destruction achieved in a Cell destruction through phagocytosis by
Type 2 Hypersensitivity Reaction? macrophages
16. What role do neutrophils play in a Type Damage to the cell by neutrophils triggering
2 Hypersensitivity Reaction? phagocytosis
17. Which cells release toxic substances to Natural killer cells
destroy the target cell in a Type 2 Hy-
persensitivity Reaction?
18. What can happen to a cell in a Type 2 Malfunction of the cell
Hypersensitivity Reaction without be-
ing destroyed?
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19. Drug allergies An example of a Type 2 reaction
20. Allergies against infectious agents An example of a Type 2 reaction
21. Hemolytic anemia An example of a Type 2 reaction
22. Blood transfusion mismatch with An example of a Type 2 reaction
transfusion reaction
23. Rh hemolytic disease An example of a Type 2 reaction
24. Graves disease An example of a Type 2 reaction
25. complement; RBC lysis Damage from ABO incompatibility occurs be-
cause of the effects of ____ on the RBC on the
membrane that results in ____.
26. Neutrophils These are the primary effector cells in Type 3
Hypersensitivity Reactions
27. Immune complex Antibody + Antigen that circulates in the blood
28. Type 3 Hypersensitivity Reaction In this hypersensitivity response, the antibody
binds to the antigen in the blood or body fluids
and then circulates to the tissue
29. not organ specific Type 3 reactions are different from Type 2 be-
cause the response is ______.
30. Autoimmune disease Immune-complex deposition overwhelms the
body because the ICDs are deposited into the
tissues causing inflammation as mononuclear
phagocytes, erythrocytes, and complement sys-
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tem fail to remove the immune complexes from
the blood.
31. Serum sickness An example of a Type 3 Hypersensitivity Reaction
32. Systemic Lupus Erythematosus (SLE) An example of a Type 3 Hypersensitivity Reaction
33. Raynaud's phenomenon An example of a Type 3 Hypersensitivity Reaction
34. Cell-mediated; delayed Type 4 Hypersensitivity Reactions are _____ and
are characterized by a ______ reaction.
35. Malnutrition This is the predominant cause of secondary im-
mune deficiencies worldwide.
36. Primary immunodeficiency A defect of the immune system such as antibody
deficiencies, B- and T-cell deficiencies, defects in
phagocytic cells, and deficiency of the comple-
ment system.
37. Secondary immunodeficiency The immune system becomes compromised be-
cause of something outside of the immune sys-
tem such as cancer, effects of drugs (ex: chemo),
and infections
38. Primary immunodeficiencies 1. Chronic granulomatous disease of childhood
2. DiGeorge syndrome
3. Job syndrome
4. Common variable immunodeficiency
5. Familial Mediterranean fever
39. Secondary immunodeficiencies 1. Human immunodeficiency virus
2. Pneumocystis carinii
3. Pneumonia
ANSWERS) NR-507: Midterm
| ALREADY Exam
GRADED A+ | VERIFIED ANSWERS | LATEST VERSIONS (JUST RELEASED)
Study online at https://quizlet.com/_gwoh5n
1. Who is at risk for hemolytic anemia? - mismatched blood types (cytotoxic Type 2 - de-
stroys RBCs)
- autoimmune hemolytic anemia d/t autoanti-
bodies against erythrocytes (seen as an antigen
and is attacked)
- allergic reaction to a drug that causes drug-in-
duced hemolytic anemia
2. Neutrophils What WBC is the first to appear in any immune
response?
3. Sensitization Occurs after an initial encounter with an allergen
4. IgE antibodies What antibodies are associated with Type 1 Hy-
persensitivity Reactions?
5. Anaphylaxis A Type 1 Hypersensitivity Reaction mediated by
IgE and mast cells where those who have been
exposed are highly sensitized
6. Inflammatory mediators Produce vasodilation, bronchial smooth muscle
contraction, and mucus production in a hyper-
sensitivity reaction
7. Urticaria An example of a Type 1 Hypersensitivity Reaction
where hives and eosinophilia are noted in the
reaction
8. Type 1 This type of hypersensitivity reaction is also con-
sidered an allergic reaction
9. Type 2
, NR-507: Midterm Exam
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This type of hypersensitivity reaction is tissue spe-
cific - aka it occurs because of happens that cause
a response mediated by IgG and IgM antibodies
10. IgG and IgM What antibodies are present in a Type 2 Hyper-
sensitivity Reaction?
11. Type 2 Hypersensitivity Reaction In this reaction, antibodies are specifically direct-
ed to the antigen located on the cell membrane,
and thus is organ specific.
12. Hapten A small molecule that can cause an immune re-
sponse when it attaches to a protein
13. Macrophages What are the primary effector cells in Type 2 Hy-
persensitivity Reactions?
14. What is the first action in a Type 2 Hy- Cell to be destroyed by the antibody
persensitivity Reaction?
15. How is cell destruction achieved in a Cell destruction through phagocytosis by
Type 2 Hypersensitivity Reaction? macrophages
16. What role do neutrophils play in a Type Damage to the cell by neutrophils triggering
2 Hypersensitivity Reaction? phagocytosis
17. Which cells release toxic substances to Natural killer cells
destroy the target cell in a Type 2 Hy-
persensitivity Reaction?
18. What can happen to a cell in a Type 2 Malfunction of the cell
Hypersensitivity Reaction without be-
ing destroyed?
, NR-507: Midterm Exam
Study online at https://quizlet.com/_gwoh5n
19. Drug allergies An example of a Type 2 reaction
20. Allergies against infectious agents An example of a Type 2 reaction
21. Hemolytic anemia An example of a Type 2 reaction
22. Blood transfusion mismatch with An example of a Type 2 reaction
transfusion reaction
23. Rh hemolytic disease An example of a Type 2 reaction
24. Graves disease An example of a Type 2 reaction
25. complement; RBC lysis Damage from ABO incompatibility occurs be-
cause of the effects of ____ on the RBC on the
membrane that results in ____.
26. Neutrophils These are the primary effector cells in Type 3
Hypersensitivity Reactions
27. Immune complex Antibody + Antigen that circulates in the blood
28. Type 3 Hypersensitivity Reaction In this hypersensitivity response, the antibody
binds to the antigen in the blood or body fluids
and then circulates to the tissue
29. not organ specific Type 3 reactions are different from Type 2 be-
cause the response is ______.
30. Autoimmune disease Immune-complex deposition overwhelms the
body because the ICDs are deposited into the
tissues causing inflammation as mononuclear
phagocytes, erythrocytes, and complement sys-
, NR-507: Midterm Exam
Study online at https://quizlet.com/_gwoh5n
tem fail to remove the immune complexes from
the blood.
31. Serum sickness An example of a Type 3 Hypersensitivity Reaction
32. Systemic Lupus Erythematosus (SLE) An example of a Type 3 Hypersensitivity Reaction
33. Raynaud's phenomenon An example of a Type 3 Hypersensitivity Reaction
34. Cell-mediated; delayed Type 4 Hypersensitivity Reactions are _____ and
are characterized by a ______ reaction.
35. Malnutrition This is the predominant cause of secondary im-
mune deficiencies worldwide.
36. Primary immunodeficiency A defect of the immune system such as antibody
deficiencies, B- and T-cell deficiencies, defects in
phagocytic cells, and deficiency of the comple-
ment system.
37. Secondary immunodeficiency The immune system becomes compromised be-
cause of something outside of the immune sys-
tem such as cancer, effects of drugs (ex: chemo),
and infections
38. Primary immunodeficiencies 1. Chronic granulomatous disease of childhood
2. DiGeorge syndrome
3. Job syndrome
4. Common variable immunodeficiency
5. Familial Mediterranean fever
39. Secondary immunodeficiencies 1. Human immunodeficiency virus
2. Pneumocystis carinii
3. Pneumonia
