, Chapter 01, General Principles of Pharmacology
1. Afterxteachingxaxgroupxofxstudentsxaboutxthexbasicsxofxpharmacology,xthexstudentsxwillxbexa
blextoxchoosexwhichxaspectxasxthexmostxcriticalxtoxremember?
A) Drugxname
B) Drugxclass
C) Drugxaction
D) Drugxsource
Answer:xC
Rationale:xPharmacologyxisxthexstudyxofxdrugsxandxitsxactionxonxlivingxorganisms.xThus,xa
nxessentialxaspectxofxpharmacologyxisxdrugxaction.xAnxunderstandingxofxthexdrugxname,xdr
ugxclass,xandxdrugxsourcexisximportant,xbutxthexmostxcriticalxaspectxrelatedxtoxpharmacolog
yxisxhowxthexdrugxactsxinxthexbody.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x1xCogni
tivexLevel:xApply
ClientxNeeds:xPhysiologicalxIntegrity:xPharmacologicalxTherapiesxInte
gratedxProcess:xTeaching/Learning
Reference:xp.x3,xIntroduction
2. Axnursexsuspectsxthexclientxhadxanxadversexreactionxtoxaxprescribedxmedicationxduexto
xanxinteractionxwithxanxunreportedxover-the-
counterxsupplement.xWhichxactionxbyxthexnursexwillxbestxassistxinxpreventingxfuturexs
imilarxincidents?
A) FilexaxreportxwithxMedWatch
B) FilexaxreportxwithxthexStatexBoardxofxNursing
C) Instructxthexclientxtoxavoidxcombiningxmedicationsxinxthexfuture
D) Documentxthexincidentxandxreportxitxtoxthexhealthxcarexprovider
Answer:xA
Rationale:xNursesxplayxanximportantxrolexinxmonitoringxforxadversexreactions.xTherefore,xit
xisximportantxtoxsubmitxreports,xevenxifxtherexisxuncertaintyxaboutxthexcause–
effectxrelationship.xThexFDAxprotectsxthexidentityxofxthosexwhoxvoluntarilyxreportxadversex
reactions.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x9xCogni
tivexLevel:xApply
, ClientxNeeds:xSafexandxEffectivexCarexEnvironment:xSafetyxandxInfectionControl
IntegratedxProcess:xClinicalxProblem-
solvingxProcessx(NursingxProcess)xReference:xp.x7,xBoxx1.1xMedWatc
hxandxReportingxAdversexEvents
3. Axnursexisxassessingxaxclientxandxnotesxthexclientxhasxdevelopedxswellingxofxthexeyelidsxa
ndxlipsxafterxadministrationxofxaxprescribedxmedication.xWhatxdoesxthexnursexinterpretxthi
sxfindingxtoxspecificallyxindicate?
A) Mildxallergicxreaction
B) Anaphylacticxshock
C) Angioedema
D) Drugxidiosyncrasy
Answer:xC
Rationale:xAngioedemaxisxaxtypexofxallergicxdrugxreactionxmanifestedxbyxthexcollectionxofx
fluidxinxthexsubcutaneousxtissues,xmostxcommonlyxaffectingxthexeyelids,xlips,xmouth,xandxt
hroat.xAllergicxreactionsxcanxbexmanifestedxbyxaxwidexrangexofxsignsxandxsymptomsxsuchx
asxitching,xrashes,xandxhives.xAnaphylacticxshockxisxaxseriousxallergicxreactionxthatxrequire
sximmediatexmedicalxattention.xDrugxidiosyncrasydescribesxanyunusualxorxabnormalxreactio
nxtoxaxdrug,xonexthatxisxdifferentxfromxthexonexnormallyxexpected.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x5xCogni
tivexLevel:xApply
ClientxNeeds:xPhysiologicalxIntegrity:xReductionxofxRiskxPotentialxIntegratedxPr
ocess:xClinicalxProblem-
solvingxProcessx(NursingxProcess)xReference:xp.x12,xAllergicxDrugxReactions
4. Thexnursexisxpreparingxtoxteachxaxclientxaboutxaxnewxdrugxwhichxisxinxthexfourthxphasexof
xdevelopment.xWhichxactivityxwillxthexnursexexplainxbestxillustratesxthisxphase?
A) HealthxcarexprovidersxreportxadversexeffectsxtoxFDA.
B) Healthyxvolunteersxarexinvolvedxinxthextest.
C) Inxvitroxtestsxarexperformedxusingxhumanxcells.
D) Thexdrugxisxgivenxtoxclientsxwithxthexdisease.
Answer:xA
, Rationale:xThexpostmarketingxsurveillancexphasexofxdrugxdevelopmentxencouragesxhealthxca
rexprofessionalsxtoxreportxadversexeffectsxofxdrugsxtoxthexFDAx usingxMedWatch.xPhasex1xofxc
linicalxtestingxinvolvesx20xtox100xhealthyxvolunteers.xInxvitroxtestingxofxthexdrugxonxhumanx
orxanimalxcellsxisxdonexinxthexpre-
FDAxphase.xInxPhasex2xofxclinicalxtesting,xthexdrugxisxgivenxtoxclientsxwithxthexdiseasexforxwh
ichxthexdrugxisxmanufactured.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x4xCogni
tivexLevel:xApply
ClientxNeeds:xHealthxPromotionxandxMaintenancexInteg
ratedxProcess:xTeaching/LearningxReference:xp.x7,xConc
eptxMasteryxAlert
5. Axnursexisxassessingxaxpregnantxclientxwhoxadmitsxtoxhavingxaxcocainexaddiction.xWh
ichxconditionxofxthexbabyxafterxbirthxshouldxthexnursexexplainxandxpreparethexclientxf
or?
A) Diabetes
B) Hypertension
C) Addictionxtoxdrugs
D) CNSxdefects
Answer:xC
Rationale:xThexnursexinformsxthexclientxthatxchildrenxbornxtoxmothersxusingxaddictivexdru
gsxarexoftenxbornxwithxanxaddictionxtoxthexdrug.xChildrenxbornxtoxmothersxwhoxarexaddic
tedxtoxcocainexarexnotxknownxtoxbexbornxwithxdiabetes,xCNSxdefects,xorxhypertension.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x6xCogni
tivexLevel:xApply
ClientxNeeds:xHealthxPromotionxandxMaintenancexIntegr
atedxProcess:xTeaching/Learning
Reference:xp.x11,xDrugxUse,xPregnancy,xandxLactation
6. Axclientxarrivesxatxthexhealthxcarexclinicxandxreportsxtakingxseveralxpillsxforxaxheadache
andxseverexcoughxwithoutxrelief.xWhichxadversexeffectxshouldxthexnursexbexawarexmayxd
evelopxfromxthisxcombination?
A) Gastrointestinalxbleeding
B) Breathingxdifficulties
C) Liverxdamage
D) Anaphylaxis
1. Afterxteachingxaxgroupxofxstudentsxaboutxthexbasicsxofxpharmacology,xthexstudentsxwillxbexa
blextoxchoosexwhichxaspectxasxthexmostxcriticalxtoxremember?
A) Drugxname
B) Drugxclass
C) Drugxaction
D) Drugxsource
Answer:xC
Rationale:xPharmacologyxisxthexstudyxofxdrugsxandxitsxactionxonxlivingxorganisms.xThus,xa
nxessentialxaspectxofxpharmacologyxisxdrugxaction.xAnxunderstandingxofxthexdrugxname,xdr
ugxclass,xandxdrugxsourcexisximportant,xbutxthexmostxcriticalxaspectxrelatedxtoxpharmacolog
yxisxhowxthexdrugxactsxinxthexbody.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x1xCogni
tivexLevel:xApply
ClientxNeeds:xPhysiologicalxIntegrity:xPharmacologicalxTherapiesxInte
gratedxProcess:xTeaching/Learning
Reference:xp.x3,xIntroduction
2. Axnursexsuspectsxthexclientxhadxanxadversexreactionxtoxaxprescribedxmedicationxduexto
xanxinteractionxwithxanxunreportedxover-the-
counterxsupplement.xWhichxactionxbyxthexnursexwillxbestxassistxinxpreventingxfuturexs
imilarxincidents?
A) FilexaxreportxwithxMedWatch
B) FilexaxreportxwithxthexStatexBoardxofxNursing
C) Instructxthexclientxtoxavoidxcombiningxmedicationsxinxthexfuture
D) Documentxthexincidentxandxreportxitxtoxthexhealthxcarexprovider
Answer:xA
Rationale:xNursesxplayxanximportantxrolexinxmonitoringxforxadversexreactions.xTherefore,xit
xisximportantxtoxsubmitxreports,xevenxifxtherexisxuncertaintyxaboutxthexcause–
effectxrelationship.xThexFDAxprotectsxthexidentityxofxthosexwhoxvoluntarilyxreportxadversex
reactions.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x9xCogni
tivexLevel:xApply
, ClientxNeeds:xSafexandxEffectivexCarexEnvironment:xSafetyxandxInfectionControl
IntegratedxProcess:xClinicalxProblem-
solvingxProcessx(NursingxProcess)xReference:xp.x7,xBoxx1.1xMedWatc
hxandxReportingxAdversexEvents
3. Axnursexisxassessingxaxclientxandxnotesxthexclientxhasxdevelopedxswellingxofxthexeyelidsxa
ndxlipsxafterxadministrationxofxaxprescribedxmedication.xWhatxdoesxthexnursexinterpretxthi
sxfindingxtoxspecificallyxindicate?
A) Mildxallergicxreaction
B) Anaphylacticxshock
C) Angioedema
D) Drugxidiosyncrasy
Answer:xC
Rationale:xAngioedemaxisxaxtypexofxallergicxdrugxreactionxmanifestedxbyxthexcollectionxofx
fluidxinxthexsubcutaneousxtissues,xmostxcommonlyxaffectingxthexeyelids,xlips,xmouth,xandxt
hroat.xAllergicxreactionsxcanxbexmanifestedxbyxaxwidexrangexofxsignsxandxsymptomsxsuchx
asxitching,xrashes,xandxhives.xAnaphylacticxshockxisxaxseriousxallergicxreactionxthatxrequire
sximmediatexmedicalxattention.xDrugxidiosyncrasydescribesxanyunusualxorxabnormalxreactio
nxtoxaxdrug,xonexthatxisxdifferentxfromxthexonexnormallyxexpected.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x5xCogni
tivexLevel:xApply
ClientxNeeds:xPhysiologicalxIntegrity:xReductionxofxRiskxPotentialxIntegratedxPr
ocess:xClinicalxProblem-
solvingxProcessx(NursingxProcess)xReference:xp.x12,xAllergicxDrugxReactions
4. Thexnursexisxpreparingxtoxteachxaxclientxaboutxaxnewxdrugxwhichxisxinxthexfourthxphasexof
xdevelopment.xWhichxactivityxwillxthexnursexexplainxbestxillustratesxthisxphase?
A) HealthxcarexprovidersxreportxadversexeffectsxtoxFDA.
B) Healthyxvolunteersxarexinvolvedxinxthextest.
C) Inxvitroxtestsxarexperformedxusingxhumanxcells.
D) Thexdrugxisxgivenxtoxclientsxwithxthexdisease.
Answer:xA
, Rationale:xThexpostmarketingxsurveillancexphasexofxdrugxdevelopmentxencouragesxhealthxca
rexprofessionalsxtoxreportxadversexeffectsxofxdrugsxtoxthexFDAx usingxMedWatch.xPhasex1xofxc
linicalxtestingxinvolvesx20xtox100xhealthyxvolunteers.xInxvitroxtestingxofxthexdrugxonxhumanx
orxanimalxcellsxisxdonexinxthexpre-
FDAxphase.xInxPhasex2xofxclinicalxtesting,xthexdrugxisxgivenxtoxclientsxwithxthexdiseasexforxwh
ichxthexdrugxisxmanufactured.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x4xCogni
tivexLevel:xApply
ClientxNeeds:xHealthxPromotionxandxMaintenancexInteg
ratedxProcess:xTeaching/LearningxReference:xp.x7,xConc
eptxMasteryxAlert
5. Axnursexisxassessingxaxpregnantxclientxwhoxadmitsxtoxhavingxaxcocainexaddiction.xWh
ichxconditionxofxthexbabyxafterxbirthxshouldxthexnursexexplainxandxpreparethexclientxf
or?
A) Diabetes
B) Hypertension
C) Addictionxtoxdrugs
D) CNSxdefects
Answer:xC
Rationale:xThexnursexinformsxthexclientxthatxchildrenxbornxtoxmothersxusingxaddictivexdru
gsxarexoftenxbornxwithxanxaddictionxtoxthexdrug.xChildrenxbornxtoxmothersxwhoxarexaddic
tedxtoxcocainexarexnotxknownxtoxbexbornxwithxdiabetes,xCNSxdefects,xorxhypertension.
QuestionxFormat:xMultiplexChoice
xChapter:x1
LearningxObjective:x6xCogni
tivexLevel:xApply
ClientxNeeds:xHealthxPromotionxandxMaintenancexIntegr
atedxProcess:xTeaching/Learning
Reference:xp.x11,xDrugxUse,xPregnancy,xandxLactation
6. Axclientxarrivesxatxthexhealthxcarexclinicxandxreportsxtakingxseveralxpillsxforxaxheadache
andxseverexcoughxwithoutxrelief.xWhichxadversexeffectxshouldxthexnursexbexawarexmayxd
evelopxfromxthisxcombination?
A) Gastrointestinalxbleeding
B) Breathingxdifficulties
C) Liverxdamage
D) Anaphylaxis
