NUR 221 Exam 2 UPDATED Exam
Questions and CORRECT Answers
any drug with similar actions to morphne - CORRECT ANSWER - opioid
endogoenous opioids - CORRECT ANSWER - found in CNS and peripheral tissue,
produced naturally by the body
two types of opioid receptors - CORRECT ANSWER - Mu and Kappa (Delta but these
arent important)
The drugs that are utilized in the treatment of duodenal and gastric ulcers competitively block
which type of histamine receptors - CORRECT ANSWER - histamine 2 receptors
types of histamine 2 blockers - CORRECT ANSWER - -cimetidine or tagamet
-stronger ones, ranitidine famotidine nazatidine
The stomach's parietal cells contain histamine₂ receptors that, when triggered - CORRECT
ANSWER - will secrete gastric acid
The concentration of hydrogen ions and gastric acid is ______________when the histamine₂
receptors are obstructed - CORRECT ANSWER - decreased
admin for cimetidine or tagamet - CORRECT ANSWER - 3-4 times a day because its
duration of action only lasts 4-5 hours
therapeutic uses of cimetidine - CORRECT ANSWER - GERD and ulcerations of GI tract
,caused by a backflow of gastric acid, and sometimes gastric contents, into the esophagus. This
results in irritation, inflammation, and, possibly, ulceration of the esophagus. - CORRECT
ANSWER - GERD (gastroesophageal reflux disease)
most commonly perscribed drugs for sx relief of GERD - CORRECT ANSWER - H2
antagonists and proton pump inhibitors
aspiration pneumonitis - CORRECT ANSWER - aspiration of gastric acids, can occur
during general anesthesia
what is used prophylactically to prevent aspiration pneumonitis - CORRECT ANSWER -
ranitidine
three routes for cimetidine - CORRECT ANSWER - PO, IM, IV
The absorption rate of cimetidine is slowed when administered - CORRECT ANSWER -
orally with food
exceretion and elimination of cimetidine - CORRECT ANSWER - minimal amount
metabolized in liver but mostly excreted in urine
half life of cimetidine with renal impairment - CORRECT ANSWER - is prolonged
is often favored over cimetidine in the treatment of Zollinger-Ellison syndrome (development of
peptic ulcers from gastric acid hyper secretion caused by a tumor-producing gastrin) because of
its higher potency and fewer side effects - CORRECT ANSWER - ranitidine
90% of those taking ranitidine have significant ulcer healing in how many weeks - CORRECT
ANSWER - 8 weeks
, T/F histamine 2 blockers are effective in treating gastric carcinoma - CORRECT
ANSWER - FALSE
cells that secrete gastric acid - CORRECT ANSWER - parietal cells
assessment of pt on histamine 2 blocker - CORRECT ANSWER - pain, GI complaints,
mental status, I&O fluid/electrolyte imbalances, gastric pH, BUN and cretaine
contraindications for cimetidine - CORRECT ANSWER - hypersensitivity, cautious with
renal impairment and older adults
contraindications and cautions for ranitidine - CORRECT ANSWER - hypersensitivity;
renal impairment, older adults, hx of porphyria, breastfeeding mothers
calcium channel blockers with cimetidine - CORRECT ANSWER - effect is intensified
histamine 2 blockers with antacids - CORRECT ANSWER - histamine 2 blocking
mechanism is lowered
oral anticoagulants and histamine 2 antagonists - CORRECT ANSWER - effects increase
assessments for those taking ranitidine or cimetidine - CORRECT ANSWER - GI bleeding
(blood in the stool), mental status changes, kidney funciton, abdominal pain or discomfort
histamine₂ blockers can have numerous adverse reactions and side effects. Some of these include
- CORRECT ANSWER - itchy skin, decreased sexual drive, impotence, constipation,
dizziness, headache, skin rash, breast enlargement in males
histamine2 blockers should be administered ___________________ and
_____________________ to prevent food induced acid secretion - CORRECT
ANSWER - at bedtime, just before meals
Questions and CORRECT Answers
any drug with similar actions to morphne - CORRECT ANSWER - opioid
endogoenous opioids - CORRECT ANSWER - found in CNS and peripheral tissue,
produced naturally by the body
two types of opioid receptors - CORRECT ANSWER - Mu and Kappa (Delta but these
arent important)
The drugs that are utilized in the treatment of duodenal and gastric ulcers competitively block
which type of histamine receptors - CORRECT ANSWER - histamine 2 receptors
types of histamine 2 blockers - CORRECT ANSWER - -cimetidine or tagamet
-stronger ones, ranitidine famotidine nazatidine
The stomach's parietal cells contain histamine₂ receptors that, when triggered - CORRECT
ANSWER - will secrete gastric acid
The concentration of hydrogen ions and gastric acid is ______________when the histamine₂
receptors are obstructed - CORRECT ANSWER - decreased
admin for cimetidine or tagamet - CORRECT ANSWER - 3-4 times a day because its
duration of action only lasts 4-5 hours
therapeutic uses of cimetidine - CORRECT ANSWER - GERD and ulcerations of GI tract
,caused by a backflow of gastric acid, and sometimes gastric contents, into the esophagus. This
results in irritation, inflammation, and, possibly, ulceration of the esophagus. - CORRECT
ANSWER - GERD (gastroesophageal reflux disease)
most commonly perscribed drugs for sx relief of GERD - CORRECT ANSWER - H2
antagonists and proton pump inhibitors
aspiration pneumonitis - CORRECT ANSWER - aspiration of gastric acids, can occur
during general anesthesia
what is used prophylactically to prevent aspiration pneumonitis - CORRECT ANSWER -
ranitidine
three routes for cimetidine - CORRECT ANSWER - PO, IM, IV
The absorption rate of cimetidine is slowed when administered - CORRECT ANSWER -
orally with food
exceretion and elimination of cimetidine - CORRECT ANSWER - minimal amount
metabolized in liver but mostly excreted in urine
half life of cimetidine with renal impairment - CORRECT ANSWER - is prolonged
is often favored over cimetidine in the treatment of Zollinger-Ellison syndrome (development of
peptic ulcers from gastric acid hyper secretion caused by a tumor-producing gastrin) because of
its higher potency and fewer side effects - CORRECT ANSWER - ranitidine
90% of those taking ranitidine have significant ulcer healing in how many weeks - CORRECT
ANSWER - 8 weeks
, T/F histamine 2 blockers are effective in treating gastric carcinoma - CORRECT
ANSWER - FALSE
cells that secrete gastric acid - CORRECT ANSWER - parietal cells
assessment of pt on histamine 2 blocker - CORRECT ANSWER - pain, GI complaints,
mental status, I&O fluid/electrolyte imbalances, gastric pH, BUN and cretaine
contraindications for cimetidine - CORRECT ANSWER - hypersensitivity, cautious with
renal impairment and older adults
contraindications and cautions for ranitidine - CORRECT ANSWER - hypersensitivity;
renal impairment, older adults, hx of porphyria, breastfeeding mothers
calcium channel blockers with cimetidine - CORRECT ANSWER - effect is intensified
histamine 2 blockers with antacids - CORRECT ANSWER - histamine 2 blocking
mechanism is lowered
oral anticoagulants and histamine 2 antagonists - CORRECT ANSWER - effects increase
assessments for those taking ranitidine or cimetidine - CORRECT ANSWER - GI bleeding
(blood in the stool), mental status changes, kidney funciton, abdominal pain or discomfort
histamine₂ blockers can have numerous adverse reactions and side effects. Some of these include
- CORRECT ANSWER - itchy skin, decreased sexual drive, impotence, constipation,
dizziness, headache, skin rash, breast enlargement in males
histamine2 blockers should be administered ___________________ and
_____________________ to prevent food induced acid secretion - CORRECT
ANSWER - at bedtime, just before meals
