MLT ASCP BOC FINAL PAPER 2025/2026 ANSWERS AND
QUESTIONS GRADED A+
is most likely to be ordered in addition to serum calcium to determine the cause of
tetany? - ✔✔Magnesium.
✔✔A 9-month-old boy from Israel has gradually lost the ability to sit up and develops
seizures. He has an increased amount of the phospholipid called Gm2-ganglioside in
his neurons and he lacks the enzyme hexosaminidase A in his leukocytes. These
findings suggest: - ✔✔Tay-Sachs disease.
✔✔An adult diabetic with renal complications has the following results:
Sodium: 133 mEq/L
BUN: 84 mg/dL
Glucose: 487 mg/dL
Creatinine: 5mg/dL
Based off these results, the calculated serum osmolality is: - ✔✔304 mOsm/kg.
✔✔The formation of estriol in a pregnant woman is dependent on: - ✔✔Fetal and
placental function.
✔✔Arterial blood collection in a heparinized syringe but exposed to room air would
cause which of the following changes in the specimen? - ✔✔pO2: Elevated.
pCO2: Decreased.
pH: Elevated.
✔✔A 50-year-old woman who has been receiving busulfan for three years for CML
becomes anemic. Lab tests reveal: Thrombocytopenia, Many peroxidase-negative blast
cells in the peripheral blood, Bone marrow hypercellular in blast transformation,
Markedly increased bone marrow TdT. Which complication is this patient most likely
experiencing? - ✔✔Acute lymphocytic leukemia.
✔✔Which is the most common cause of an abnormality in hemostasis? -
✔✔Quantitative abnormality of platelets.
✔✔A leukocyte count and differential on a 40-year-old Caucasian male reveals...this
data represents: - ✔✔Absolute neutropenia.
✔✔A patient has a normal PTT and a prolonged APTT using a kaolin activator. The
APTT corrects to normal when the incubation is increased. These results suggest the
patient has: - ✔✔Fletcher factor deficiency (prekallikrein.)
, ✔✔Elevation of the TOTAL granulocyte count above 9.0 x 10^3/uL is termed: -
✔✔Absolute neutrophilic leukocytosis.
✔✔The most appropriate screening test for hemoglobin H is: - ✔✔Heat instability test.
✔✔PT - 20 sec.
Thrombin time - 13 sec.
APTT - 55 secs.
APTT plus aged serum - Corrected.
APTT plus absorbed plasma - Not corrected.
Circulatory inhibitor - None present.
Which coagulation factor is deficient? - ✔✔Factor X.
✔✔Which laboratory procedure is most helpful in differentiating severe liver disease
accompanying secondary fibrinolysis from disseminated intravascular coagulation? -
✔✔Factor VIII activity.
✔✔Which laboratory finding is associated with Factor XIII deficiency? - ✔✔Clot solubility
in a 5M urea solution.
✔✔An automated leukocyte count is 22.5 x 10^3/uL. The differential reveals 200
normoblasts/100 leukocytes. What is the actual leukocyte count per microliter? -
✔✔7,500/uL.
✔✔On Monday, a patient's hemoglobin was 11.3 g/dL and on Tuesday it measured 11.8
g/dL. The standard deviation of the method used is +/- 0.2 g/dL. What can be concluded
about the hemoglobin values given? - ✔✔There is no significant change in the patient's
hemoglobin concentration.
✔✔Patients suffering from Waldenstrom's macroglobulinemia demonstrate excessively
increased concentrations of: - ✔✔IgM.
✔✔The disappeareance of HBsAG and HbeAg, the persistence of anti-HBc, the
appearance of anti-HBs, and often of anti-Hbe indicate: - ✔✔Recovery phase of acute
HBV hepatitis.
✔✔The stock cultures needed for quality control testing of DEAMINATION ACTIVITY
are: - ✔✔Proteus mirabilis/Escherichia coli.
✔✔What is the most reliable test to differentiate N. lactamica from N. meningitidis? -
✔✔Lactose degradation.
QUESTIONS GRADED A+
is most likely to be ordered in addition to serum calcium to determine the cause of
tetany? - ✔✔Magnesium.
✔✔A 9-month-old boy from Israel has gradually lost the ability to sit up and develops
seizures. He has an increased amount of the phospholipid called Gm2-ganglioside in
his neurons and he lacks the enzyme hexosaminidase A in his leukocytes. These
findings suggest: - ✔✔Tay-Sachs disease.
✔✔An adult diabetic with renal complications has the following results:
Sodium: 133 mEq/L
BUN: 84 mg/dL
Glucose: 487 mg/dL
Creatinine: 5mg/dL
Based off these results, the calculated serum osmolality is: - ✔✔304 mOsm/kg.
✔✔The formation of estriol in a pregnant woman is dependent on: - ✔✔Fetal and
placental function.
✔✔Arterial blood collection in a heparinized syringe but exposed to room air would
cause which of the following changes in the specimen? - ✔✔pO2: Elevated.
pCO2: Decreased.
pH: Elevated.
✔✔A 50-year-old woman who has been receiving busulfan for three years for CML
becomes anemic. Lab tests reveal: Thrombocytopenia, Many peroxidase-negative blast
cells in the peripheral blood, Bone marrow hypercellular in blast transformation,
Markedly increased bone marrow TdT. Which complication is this patient most likely
experiencing? - ✔✔Acute lymphocytic leukemia.
✔✔Which is the most common cause of an abnormality in hemostasis? -
✔✔Quantitative abnormality of platelets.
✔✔A leukocyte count and differential on a 40-year-old Caucasian male reveals...this
data represents: - ✔✔Absolute neutropenia.
✔✔A patient has a normal PTT and a prolonged APTT using a kaolin activator. The
APTT corrects to normal when the incubation is increased. These results suggest the
patient has: - ✔✔Fletcher factor deficiency (prekallikrein.)
, ✔✔Elevation of the TOTAL granulocyte count above 9.0 x 10^3/uL is termed: -
✔✔Absolute neutrophilic leukocytosis.
✔✔The most appropriate screening test for hemoglobin H is: - ✔✔Heat instability test.
✔✔PT - 20 sec.
Thrombin time - 13 sec.
APTT - 55 secs.
APTT plus aged serum - Corrected.
APTT plus absorbed plasma - Not corrected.
Circulatory inhibitor - None present.
Which coagulation factor is deficient? - ✔✔Factor X.
✔✔Which laboratory procedure is most helpful in differentiating severe liver disease
accompanying secondary fibrinolysis from disseminated intravascular coagulation? -
✔✔Factor VIII activity.
✔✔Which laboratory finding is associated with Factor XIII deficiency? - ✔✔Clot solubility
in a 5M urea solution.
✔✔An automated leukocyte count is 22.5 x 10^3/uL. The differential reveals 200
normoblasts/100 leukocytes. What is the actual leukocyte count per microliter? -
✔✔7,500/uL.
✔✔On Monday, a patient's hemoglobin was 11.3 g/dL and on Tuesday it measured 11.8
g/dL. The standard deviation of the method used is +/- 0.2 g/dL. What can be concluded
about the hemoglobin values given? - ✔✔There is no significant change in the patient's
hemoglobin concentration.
✔✔Patients suffering from Waldenstrom's macroglobulinemia demonstrate excessively
increased concentrations of: - ✔✔IgM.
✔✔The disappeareance of HBsAG and HbeAg, the persistence of anti-HBc, the
appearance of anti-HBs, and often of anti-Hbe indicate: - ✔✔Recovery phase of acute
HBV hepatitis.
✔✔The stock cultures needed for quality control testing of DEAMINATION ACTIVITY
are: - ✔✔Proteus mirabilis/Escherichia coli.
✔✔What is the most reliable test to differentiate N. lactamica from N. meningitidis? -
✔✔Lactose degradation.
