harmaceutical Chemistry exam questions with answers

Pharmaceutical Chemistry exam questions \| \| \| \|




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What does DMPK stand for? - CORRECT ANSWERS ✔✔Drug Metabolism
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and Pharmokinetic
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What are physicochemical properties important considerations for? -
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CORRECT ANSWERS ✔✔Dosage formulation, pharmacokinetics,
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pharmacologic action, and adverse effects \| \| \| \|




What do the reactive properites of individual functional groups determine? -
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CORRECT ANSWERS ✔✔Chemical stabilities and metabolic transformations
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What are the physicochemical properties? - CORRECT ANSWERS ✔✔Acid-
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base properties and water-lipid solubility
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What does ADME stand for? - CORRECT ANSWERS ✔✔Absorption,
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Distribution, Metabolism , and Elimination \| \| \| \|




What determines the biological activities exhibited by a drug? - CORRECT
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ANSWERS ✔✔The physicochemical properties of the individual functional
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groups and their relative locations/size in 3 dimensional space.
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, What effects can a functional group have on the same molecule? - CORRECT
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ANSWERS ✔✔Steric, electronic, noncovalent bonding,
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charge, hydrophilic/hydrophobic, and electrophilic/nucleophilic reactivity
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What are the noncovalent bonds? - CORRECT ANSWERS ✔✔Ionic bond,
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dipole bond, van der waals interactions, hydrophobic bond,
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and chelation/complexation
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What are the three kinds of dipole bonds? - CORRECT ANSWERS ✔✔Ion-
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dipole, dipole-dipole, and hydrogen bonds
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What are the three kinds of Van der Waals interactions - CORRECT
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ANSWERS ✔✔Keesom interaction, Debye force and London dispersion force
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What are ionic bonds? - CORRECT ANSWERS ✔✔Also known as
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electrostatic attractive forces. Are attractive forces between two oppositely
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charged ions. \|




What is the bond strength of an ionic bond determined by? - CORRECT
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ANSWERS ✔✔The charges of the two moeities and is inversely proportional
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to the distance betwen the charges and the dielectric constant of the solven
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What atoms can create a dipole when bound to carbon? - CORRECT
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ANSWERS ✔✔Oxygen, nitrogen, and sulfur \| \| \| \|