D115 master set-Advanced Pathophysiology for
the Advanced Practice Nurse
Which type of genetic disease affects males
more frequently than females? -
Answer✅️ ☑S ️ex-Linked recessive. Since males
only have one X and one Y, if the affected
chromosome has the illness, it will be
expressed.
In which two conditions are chromosomal
abnormalities the leading known cause? -
Answer✅️ ☑I️ntellectual disability and fetal
miscarriage. Chromosome abnormalities are
the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal
diagnostic studies? - Answer✅️☑️Chorionic
villus sampling (CVS), amniocentesis, and
,preimplantation genetic testing (PGT) are
examples of prenatal diagnostic studies and
are performed in vitro. CVS is a form of
genetic testing that provides genetic
information found in utero and is usually
performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of
genetic testing that evaluates amniotic fluid
and is usually performed during the second
trimester, between weeks 15 and 20 of
pregnancy. PGT is performed on the embryo
prior to implantation.
Which genetic disorder is characterized by the
presence of a zygote having one chromosome
with a normal complement of genes and one
chromosome with a missing gene? -
Answer✅️ ☑C️ ri du chat syndrome (translated
as "cry of the cat") is caused by a DNA
deletion. This term describes the cry often
heard from a baby affected by the syndrome.
Cri du chat syndrome can present as a
,microcephalic, low birth-weight baby with a
piercing cry.
How can an X-linked recessive disease skip
generations? - Answer✅️ ☑️The disease can be
transmitted through female carriers.
Since females have two copies of the X
chromosome, the mother may provide an
unaffected X to a daughter or son.
Furthermore, a daughter may not show signs
of the disease because she has the other X
(the only X the father can give to a female) to
cancel it out.
Which type of risk is referred to as the ratio of
the disease rate among the entire population
to the disease rate in an unexposed
population? - Answer✅️ ☑️Relative risk is a
ratio of probability, not an actual occurrence
of disease.
, What are the empirical risks for most
multifactorial diseases based on? -
Answer✅️ ☑M ️any factors from lifestyle to
genetics affect multifactorial diseases.
Observation and evaluation of each case
individually provides the most thorough and
accurate assessment.
What refers to the silenced gene of a gene
pair. - Answer✅️ ☑️The imprinted gene is the
silent gene of a gene pair.
What is the primary reason that some older
adults have impaired inflammation and wound
healing? - Answer✅️ ☑️The underlying chronic
illness exists.
A generalized inflammatory response seen in
chronic illness depletes the body's reserves to
fight against illness.
Which cells are the body's primary defense
against parasite invasion? -
the Advanced Practice Nurse
Which type of genetic disease affects males
more frequently than females? -
Answer✅️ ☑S ️ex-Linked recessive. Since males
only have one X and one Y, if the affected
chromosome has the illness, it will be
expressed.
In which two conditions are chromosomal
abnormalities the leading known cause? -
Answer✅️ ☑I️ntellectual disability and fetal
miscarriage. Chromosome abnormalities are
the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal
diagnostic studies? - Answer✅️☑️Chorionic
villus sampling (CVS), amniocentesis, and
,preimplantation genetic testing (PGT) are
examples of prenatal diagnostic studies and
are performed in vitro. CVS is a form of
genetic testing that provides genetic
information found in utero and is usually
performed between weeks 11 and 14 of
pregnancy. An amniocentesis is a form of
genetic testing that evaluates amniotic fluid
and is usually performed during the second
trimester, between weeks 15 and 20 of
pregnancy. PGT is performed on the embryo
prior to implantation.
Which genetic disorder is characterized by the
presence of a zygote having one chromosome
with a normal complement of genes and one
chromosome with a missing gene? -
Answer✅️ ☑C️ ri du chat syndrome (translated
as "cry of the cat") is caused by a DNA
deletion. This term describes the cry often
heard from a baby affected by the syndrome.
Cri du chat syndrome can present as a
,microcephalic, low birth-weight baby with a
piercing cry.
How can an X-linked recessive disease skip
generations? - Answer✅️ ☑️The disease can be
transmitted through female carriers.
Since females have two copies of the X
chromosome, the mother may provide an
unaffected X to a daughter or son.
Furthermore, a daughter may not show signs
of the disease because she has the other X
(the only X the father can give to a female) to
cancel it out.
Which type of risk is referred to as the ratio of
the disease rate among the entire population
to the disease rate in an unexposed
population? - Answer✅️ ☑️Relative risk is a
ratio of probability, not an actual occurrence
of disease.
, What are the empirical risks for most
multifactorial diseases based on? -
Answer✅️ ☑M ️any factors from lifestyle to
genetics affect multifactorial diseases.
Observation and evaluation of each case
individually provides the most thorough and
accurate assessment.
What refers to the silenced gene of a gene
pair. - Answer✅️ ☑️The imprinted gene is the
silent gene of a gene pair.
What is the primary reason that some older
adults have impaired inflammation and wound
healing? - Answer✅️ ☑️The underlying chronic
illness exists.
A generalized inflammatory response seen in
chronic illness depletes the body's reserves to
fight against illness.
Which cells are the body's primary defense
against parasite invasion? -
